关键词: 短暂性脑缺血发作, 经颅彩色多普勒超声, 血流参数, 颈动脉狭窄

Abstract: To investigate the value of transcranial color code sonography (TCCS) blood flow parameters in the diagnosis of carotid stenosis in patients with transient ischemic attack (TIA). TIA patients were selected as the study group and healthy people in the same period were selected as the control group. Both groups were given DSA examination and TCCS examination.DSA examination results were used as the gold standard to analyze the diagnostic efficiency of TCCS blood flow parameters on carotid stenosis. The results showed that the PSV, EDV, MFV, PI and RI of the positive side of carotid stenosis in the study group were all higher than those of the negative side and the control group (P<0.05). ROC curve analysis results showed that, the best cut-off points of TCCS blood flow parameters in the diagnosis of mild, moderate and severe carotid stenosis were PSV ≥ 110 cm/s or MFV ≥ 65 cm/s, PSV ≥ 145 cm/s or MFV ≥ 85 cm/s, PSV ≥ 190 cm/s or MFV ≥ 115 cm/s, respectively. The coincidence rate of the best cut-off points of TCCS blood flow parameters in the diagnosis of mild, moderate and severe carotid stenosis was good agreement with DSA (Kappa=0.875, P=0.000). Therefore, TCCS blood flow parameters can effectively monitor the hemodynamic changes in patients with TIA, and have high diagnostic value for carotid stenosis.

Key words: transient ischemic attack (TIA), transcranial color code sonography ((TCCS), blood flow parameters, carotid stenosis