影像科学与光化学 ›› 2020, Vol. 38 ›› Issue (4): 676-680.DOI: 10.7517/issn.1674-0475.191221

• 综述与论文 • 上一篇    下一篇

肺部超声联合血清PCT、CRP对儿童社区获得性肺炎的诊断效能研究

李玉, 尹晓   

  1. 十堰市妇幼保健院 儿童保健科, 湖北 十堰 442000
  • 收稿日期:2019-12-24 出版日期:2020-07-15 发布日期:2020-07-15

The Diagnostic Efficacy of Lung Ultrasound Combined with Serum PCT and CRP on the Community Acquired Pneumonia in Children

LI Yu, YIN Xiao   

  1. Department of Child Health Care, Shiyan Maternal and Child Health Hospital, Shiyan 442000, Hubei, P. R. China
  • Received:2019-12-24 Online:2020-07-15 Published:2020-07-15

摘要: 为分析肺部超声(LUS)联合血清降钙素原(PCT)、C反应蛋白(CRP)在儿童社区获得性肺炎(CAP)诊断中的应用价值,本研究选取疑似CAP患儿176例,均给予胸部CT、LUS及血清PCT、CRP检查。以胸部CT诊断结果为参照,将患儿分为CAP组(102例)和非CAP组(74例),比较两组LUS特征及血清PCT、CRP水平,并用ROC曲线分析LUS联合血清PCT、CRP的诊断效能。结果显示,CAP组患儿的肺泡间质综合征、肺实变、胸膜线异常、支气管征、胸腔积液及血清PCT、CRP水平均高于非CAP组(P<0.05)。LUS联合血清PCT、CRP诊断儿童CAP的AUC、敏感度、特异度均高于单项检查(P<0.05)。因此,LUS联合血清PCT、CRP检查可提高对儿童CAP的诊断效能。

关键词: 儿童, 社区获得性肺炎, 肺部超声, 降钙素原, C反应蛋白, 诊断效能

Abstract: The efficacy of lung ultrasound (LUS) combined with serum procalcitonin (PCT) and C-reactive protein (CRP) in the diagnosis of community acquired pneumonia (CAP) in children is analyzed in this study. 176 children with CAP from February 2017 to November 2019 were selected and examined by chest CT, as well as the serum PCT and CRP. The results of the chest CT were the diagnostic criteria, the children were divided into CAP group (102 cases) and N-CAP group (74 cases). The LUS characteristics and the levels of serum PCT, CRP were compared. The diagnostic efficacy of LUS combined with PCT and CRP was analyzed by ROC curve. The results showed that, the pulmonary interstitial syndrome, pulmonary consolidation, abnormal pleura line, bronchus syndrome, pleural effusion and the levels of serum PCT, CRP of CAP group were higher than those of the N-CAP group, and the difference was statistically significant (P<0.05). The AUC, sensitivity and specificity of LUS combined with PCT and CRP in the diagnosis of CAP in children were higher than those of the single examination (P<0.05). Therefore, LUS combined with PCT and CRP can improve the diagnostic efficacy of CAP in children.

Key words: children, community acquired pneumonia, lung ultrasound, procalcitonin, C-reactive protein, diagnostic efficacy