关键词: 儿童, 青少年, 甲状腺乳头状癌, 超声特征, 临床病理特征

Abstract: Children and adolescents with papillary thyroid carcinoma (PTC) are rare, but their differences in sonographic and pathologic features are significant. A total of 34 consecutive patients including pathologically confirmed children (age ≤ 15 years) and adolescents (15-18 years) with papillary thyroid carcinoma (PTC) were recruited. We retrospectively analyzed the preoperative ultrasonography and pathology features, compared the difference of them. The incidence of gender in children and adolescents (male vs. female) were 3:5 vs.1:17 (P=0.020). Moreover, the presence of punctate echogenic foci on sonography was 93.8% vs. 50.0%. The presence of neck lymph node metastasis was 87.5% vs. 44.4%, and the ratio of category 5 nodules in ACR TI-RADS was 93.8% vs. 50.0% in children and adolescents patients (P<0.05). The histopathology ratio of staging N0, N1a and N1b in children and 849 adolescent groups were 4:5:7 and 6:11:1 (P=0.029), the ratio of pTNM staging Ⅰ and Ⅱ were 8:8 and 15:3 (P=0.038), respectively. In conclusion, the PTC in children have specific ultrasonography and pathology features, which were different from those of adolescent.

Key words: children, adolescents, papillary thyroid carcinoma, thyroid ultrasonography, pathology features