硬膜外导管持续冲洗下钬激光碎石术对高CT值输尿管结石的治疗效果研究

doi:10.7517/issn.1674-0475.200519

影像科学与光化学 ›› 2020, Vol. 38 ›› Issue (6): 1070-1075.DOI: 10.7517/issn.1674-0475.200519

硬膜外导管持续冲洗下钬激光碎石术对高CT值输尿管结石的治疗效果研究

刘强, 邵敬会, 臧洪学, 李帅彪

保定市第四中心医院, 河北保定 072350

收稿日期:2020-05-21 出版日期:2020-11-15 发布日期:2020-11-15
通讯作者: 邵敬会

The Therapeutic Effect of HLL Under Continuous Irrigation of Epidural Catheter in Ureteral Calculi with High CT Value

LIU Qiang, SHAO Jinghui, ZANG Hongxue, LI Shuaibiao

The Fourth Central Hospital of Baoding City, Baoding 072350, Hebei, P. R. China

Received:2020-05-21 Online:2020-11-15 Published:2020-11-15

摘要/Abstract

摘要： 本文探讨了硬膜外导管持续冲洗下钬激光碎石术（HLL）对高CT值输尿管结石的治疗效果。纳入106例高CT值输尿管结石患者，用随机数字表法均分为两组，对照组采用输尿管镜下HLL，观察组采用硬膜外导管持续冲洗下HLL。观察组手术时间短于对照组，碎石成功率高于对照组，结石上移率、体外碎石率低于对照组（P<0.05）。术后1 d观察组患者肾上腺素（AE）、皮质醇（Cor）、丙二醛（MDA）均值低于对照组，超氧化物歧化酶（SOD）均值高于对照组。术后3 d观察组患者白介素-1（IL-1）、肿瘤坏死因子-α（TNF-α）、IL-6水平均值低于对照组（P<0.05）。观察组并发症发生率（3.77%）低于对照组（15.09%，P<0.05）。本研究提示采用硬膜外导管持续冲洗下HLL治疗高CT值输尿管结石效果更佳。

关键词: 硬膜外导管, 钬激光, 高CT值, 输尿管结石, 肾功能, 应激反应, 碎石率

Abstract: The aim of this research is to explore the therapeutic effect of holmium laser lithotripsy (HLL) under continuous irrigation by epidural catheter in the treatment of ureteral calculi of high CT value. A total of 106 patients with ureteral calculi of high CT values were divided into two groups by random number table. The control group adopted HLL under ureteroscopy, and the observation group adopted HLL under continuous irrigation by epidural catheter. The operation time of the observation group was shorter than that of the control group, while the success rate of lithotripsy was higher than that of the control group, and the rate of stone uplift and in vitro lithotripsy was lower than that of the control group (P<0.05). One day after surgery, the adrenaline (AE), cortisol (Cor), and malondialdehyde (MDA) of the observation group were lower than those of the control group, while the superoxide dismutase (SOD) was higher than that of the control group. Three days after surgery, the interleukin-1 (IL-1), tumor necrosis factor-α (TNF-α) and IL-6 in the observation group were lower than those in the control group (P<0.05). The incidence of complications in the observation group (3.77%) was significantly lower than that in the control group (15.09%). It is suggested that HLL under continuous irrigation by epidural catheter is more effective in treating ureteral calculi of high CT value.

Key words: epidural catheter, holmium laser, high CT value, ureteral calculi, renal function, stress response, lithotripsy rate

刘强, 邵敬会, 臧洪学, 李帅彪. 硬膜外导管持续冲洗下钬激光碎石术对高CT值输尿管结石的治疗效果研究[J]. 影像科学与光化学, 2020, 38(6): 1070-1075.

LIU Qiang, SHAO Jinghui, ZANG Hongxue, LI Shuaibiao. The Therapeutic Effect of HLL Under Continuous Irrigation of Epidural Catheter in Ureteral Calculi with High CT Value[J]. Imaging Science and Photochemistry, 2020, 38(6): 1070-1075.

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硬膜外导管持续冲洗下钬激光碎石术对高CT值输尿管结石的治疗效果研究

The Therapeutic Effect of HLL Under Continuous Irrigation of Epidural Catheter in Ureteral Calculi with High CT Value

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