磁共振扩散加权成像联合血清AFP对小肝癌临床诊断及疗效评估的价值

doi:10.7517/issn.1674-0475.200714

影像科学与光化学 ›› 2021, Vol. 39 ›› Issue (1): 75-80.DOI: 10.7517/issn.1674-0475.200714

磁共振扩散加权成像联合血清AFP对小肝癌临床诊断及疗效评估的价值

张化冰, 齐杰, 高战强, 刘术昌, 焦健, 冯磊

廊坊市第四人民医院, 河北廊坊 065000

收稿日期:2020-07-23 发布日期:2021-01-13
通讯作者: 张化冰
基金资助:
廊坊市科学技术研究与发展计划项目（2017013034）

The Value of DWI-MRI Combined with Serum AFP in the Clinical Diagnosis and Efficacy Evaluation of Small Hepatocellular Carcinoma

ZHANG Huabing, QI Jie, GAO Zhanqiang, LIU Shuchang, JIAO Jian, FENG Lei

Langfang Fourth People's Hospital, Langfang 065000, Hebei, P. R. China

Received:2020-07-23 Published:2021-01-13

摘要/Abstract

摘要： 将194例小肝癌患者纳入小肝癌组，185例肝细胞结节患者纳入结节组，所有患者均行MRI扩散加权成像（DWI-MRI），评估患者在DWI-MRI上的形态学表现及ADC值，检测患者血清AFP水平，比较不同检测方法诊断小肝癌的准确度、灵敏度、特异度。结果显示，应用DWI-MRI联合血清AFP诊断小肝癌的特异度、灵敏度和准确度均显著高于单独应用DWI-MRI，或血清AFP（P<0.05）。表明DWI-MRI联合血清AFP对小肝癌的诊断价值显著，可为病情评估提供切实可行的参考。

关键词: 小肝癌, MRI扩散加权成像, AFP, 诊断价值

Abstract: A total of 194 patients with small hepatocellular carcinoma were enrolled and include in the small hepatocellular carcinoma group. In addition, 185 patients with hepatocellular nodules were included in the nodule group. All patients underwent diffusion-weighted magnetic resonance imaging (DWI-MRI) to evaluate the morphological performance and ADC value on DWI-MRI. Serum AFP levels were also detected. The accuracy, sensitivity, and specificity of DWI-MRI, AFP, and combination of those were compared. The results showed that the diagnostic specificity, sensitivity and accuracy of DWI-MRI combined with serum AFP were significantly higher than that of DWI-MRI, or serum AFP alone (P<0.05). The above results suggest that DWI-MRI combined with serum AFP has significant diagnostic value for small hepatocellular carcinoma, which can provide a practical reference for disease evaluation.

Key words: small hepatocellular carcinoma, diffusion-weighted magnetic resonance imaging (DWI-MRI), alpha-fetoprotein (AFP), diagnostic value

张化冰, 齐杰, 高战强, 刘术昌, 焦健, 冯磊. 磁共振扩散加权成像联合血清AFP对小肝癌临床诊断及疗效评估的价值[J]. 影像科学与光化学, 2021, 39(1): 75-80.

ZHANG Huabing, QI Jie, GAO Zhanqiang, LIU Shuchang, JIAO Jian, FENG Lei. The Value of DWI-MRI Combined with Serum AFP in the Clinical Diagnosis and Efficacy Evaluation of Small Hepatocellular Carcinoma[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2021, 39(1): 75-80.

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磁共振扩散加权成像联合血清AFP对小肝癌临床诊断及疗效评估的价值

The Value of DWI-MRI Combined with Serum AFP in the Clinical Diagnosis and Efficacy Evaluation of Small Hepatocellular Carcinoma

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