单手性半导体碳纳米管在生物成像中的研究进展

doi:10.7517/issn.1674-0475.210402

影像科学与光化学 ›› 2021, Vol. 39 ›› Issue (3): 348-353.DOI: 10.7517/issn.1674-0475.210402

单手性半导体碳纳米管在生物成像中的研究进展

许文静^1,2, 侯军才¹, 赵建文²

1. 陕西理工大学材料科学与工程学院, 陕西汉中 723000;
2. 中国科学院苏州纳米技术与纳米仿生研究所印刷电子研究中心, 江苏苏州 215123

收稿日期:2021-03-30 出版日期:2021-05-15 发布日期:2021-05-17
通讯作者: 侯军才, 赵建文
基金资助:
国家重点研发计划（2020YFA0714700）、国家自然基金面上项目（61874132）和陕西省自然基金面上项目（2017JM5063）

Recent Progress of Biological Imaging Based on Monochiral Semiconducting Single-walled Carbon Nanotubes

XU Wenjing^1,2, HOU Juncai¹, ZHAO Jianwen²

1. School of Materials Science and Engineering, Shaanxi University of Technology, Hanzhong 723000, Shaanxi, P. R. China;
2. Printable Electronics Research Centre, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, Jiangsu, P. R. China

Received:2021-03-30 Online:2021-05-15 Published:2021-05-17

摘要/Abstract

摘要： 半导体碳纳米管在生物成像、光热疗法和运载药物等生物医学应用中都展现出明显的优势。特别是生物成像，半导体碳纳米管在近红外生物窗口（0.7~1.4 μm）中显示出固有的荧光和强大的光学吸收。半导体碳纳米管不仅可以在体内深层成像中对细胞进行荧光标记，还可以追踪和治疗肿瘤细胞。半导体碳纳米管的电子能带结构和光、电性能均取决于它们的手性，应用于生物医学时，只有采用单手性半导体碳纳米管才能最大限度展现出碳纳米管本身的优势。单手性半导体碳纳米管的分离及其在新型光电子器件和生物荧光成像等相关应用一直是当今科技前沿中的研究热点。本论文将介绍半导体碳纳米管的分离技术和单手性碳纳米管在生物成像领域的研究进展。

关键词: 半导体碳纳米管, 单手性, 分离技术, 生物成像

Abstract: Semiconducting single-walled carbon nanotubes (sc-SWCNTs) have shown obvious advantages in biomedical applications such as biological imaging, photothermal therapy and drug delivery. In particular, they exhibit excellent properties for biological imaging due to their inherent fluorescence and strong optical absorption in the near infrared biological window (0.7-1.4 μm). Sc-SWCNT can be used in not only fluorescently labeling cells in deep imaging in vivo, but also tracking and treating tumor cells, which have attracted widespread attention. The electronic band structure and photoelectric properties of sc-SWCNTs depend on their chirality. The advantages of sc-SWCNTs themselves can be maximized only when using monochiral sc-SWCNTs for biomedical applications. The separation of monochiral sc-SWCNTs and their applications in new optoelectronic devices and bioluminescence imaging have become research hotspots at the forefront of science and technology. In this paper, we will introduce the separation technology of sc-SWCNTs and the research progress of monochiral sc-SWCNTs in the field of biological imaging.

Key words: semiconducting single-walled carbon nanotubes, monochiral, separation technology, biological imaging

许文静, 侯军才, 赵建文. 单手性半导体碳纳米管在生物成像中的研究进展[J]. 影像科学与光化学, 2021, 39(3): 348-353.

XU Wenjing, HOU Juncai, ZHAO Jianwen. Recent Progress of Biological Imaging Based on Monochiral Semiconducting Single-walled Carbon Nanotubes[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2021, 39(3): 348-353.

参考文献

[1] Yang F, Wang M, Zhang D, et al. Chirality pure carbon nanotubes:growth, sorting, and characterization[J]. Chemical Reviews, 2020,120(5):2693-2758.
[2] Rojas W A G, Hersam M C. Chirality-enriched carbon nanotubes for next-generation computing[J]. Advanced Materials, 2020,32(41):1905654.
[3] Welsher K, Sherlock S P, Dai H, et al. Deep-tissue anatomical imaging of mice using carbon nanotube fluorophores in the second near-infrared window[J]. Proceedings of the National Academy of Sciences of the United States of America, 2011,108(22):8943-8948.
[4] Avouris P, Freitag M, Perebeinos V, et al. Carbon-nanotube photonics and optoelectronics[J]. Nature Photonics, 2008,2(6):341-350.
[5] Journet C, Maser W K, Bernier P, et al. Large-scale production of single-walled carbon nanotubes by the electric-arc technique[J]. Nature, 1997,388:756-758.
[6] Guo T, Nikolaev P, Thess A, et al. Catalytic growth of single-walled manotubes by laser vaporization[J]. Chemical Physics Letters, 1995,243(1-2):49-54.
[7] Kim K S, Cota-Sanchez G, Kingston C T, et al. Large-scale production of single-walled carbon nanotubes by induction thermal plasma[J]. Journal of Physics D:Applied Physics, 2007,40(8):2375-2387.
[8] Meyyappan M, Delzeit L, Cassell A, et al. Carbon nanotube growth by PECVD:a review[J]. Plasma Sources Science and Technology, 2003,12(2):205.
[9] Li W Z, Xie S S, Qian L X, et al. Large-scale synthesis of aligned carbon nanotubes[J]. Science, 1996,274(5293):1701-1703.
[10] Kitiyanan B, Alvarez W E, Harwell J H, et al. Controlled production of single-wall carbon nanotubes by catalytic decomposition of CO on bimetallic Co-Mo catalysts[J]. Chemical Physics Letters, 2000,317(3-5):497-503.
[11] Liu H, Nishide D, Tanaka T, et al. Large-scale single-chirality separation of single-wall carbon nanotubes by simple gel chromatography[J]. Nature Communications, 2011,2(1):1-8.
[12] Arnold M S, Green A A, Hulvat J F, et al. Sorting carbon nanotubes by electronic structure using density differentiation[J]. Nature Nanotechnology, 2006,1(1):60-65.
[13] Arnold M S, Stupp S I, Hersam M C. Enrichment of single-walled carbon nanotubes by diameter in density gradients[J]. Nano Letters, 2005,5(4):713-718.
[14] Khripin C Y, Fagan J A, Zheng M. Spontaneous partition of carbon nanotubes in polymer-modified aqueous phases[J]. Journal of the American Chemical Society, 2013,135(18):6822-6825.
[15] Nish A, Hwang J Y, Doig J, et al. Highly selective dispersion of single-walled carbon nanotubes using aromatic polymers[J]. Nature Nanotechnology, 2007,2(10):640-646.
[16] Diao S, Hong G, Robinson J T, et al. Chirality enriched (12,1) and (11,3) single-walled carbon nanotubes for biological imaging[J]. Journal of the American Chemical Society, 2012,134(41):16971-16974.
[17] Antaris A L, Robinson J T, Yaghi O K, et al. Ultra-low doses of chirality sorted (6,5) carbon nanotubes for simultaneous tumor imaging and photothermal therapy[J]. ACS Nano, 2013,7(4):3644-3652.
[18] Hong G, Diao S, Antaris A L, et al. Carbon nanomaterials for biological imaging and nanomedicinal therapy[J]. Chemical Reviews, 2015,115(19):10816-10906.
[19] Antaris A L, Yaghi O K, Hong G, et al. Single chirality (6,4) single-walled carbon nanotubes for fluorescence imaging with silicon detectors[J]. Small (Weinheim an der Bergstrasse, Germany), 2015,11(47):6325-6330.
[20] Yomogida Y, Tanaka T, Zhang M, et al. Industrial-scale separation of high-purity single-chirality single-wall carbon nanotubes for biological imaging[J]. Nature Communications, 2016,7(1):12056-12064.
[21] Bashkatov A N, Genina E A, Kochubey V I, et al. Optical properties of human skin, subcutaneous and mucous tissues in the wavelength range from 400 to 2000 nm[J]. Journal of Physics D-Applied Physics, 2005,38(15):2543-2555.
[22] Robinson J T, Hong G, Liang Y, et al. In vivo fluorescence imaging in the second near-infrared window with long circulating carbon nanotubes[J]. Journal of the American Chemical Society, 2012,134(25):10664-10669.
[23] Chaffer C L, Weinberg R A. A Perspective on Cancer Cell Metastasis[J]. Science, 2011,331(6024):1559-1564.
[24] Ghosh S, Bachilo S M, Simonette R A, et al. Oxygen doping modifies near-infrared band gaps in fluorescent single-walled carbon nanotubes[J]. Science, 2010,330(6011):1656-1659.
[25] Sekiyama S, Umezawa M, Iizumi Y, et al. Delayed increase in near-infrared fluorescence in cultured murine cancer cells labeled with oxygen-doped single-walled carbon nanotubes[J]. Langmuir, 2019,35(3):831-837.
[26] Liu B, Wu F, Gui H, et al. Chirality-controlled synthesis and applications of single-wall carbon nanotubes[J]. ACS Nano, 2017,11(1):31-53.

单手性半导体碳纳米管在生物成像中的研究进展

Recent Progress of Biological Imaging Based on Monochiral Semiconducting Single-walled Carbon Nanotubes

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