影像科学与光化学 ›› 2022, Vol. 40 ›› Issue (3): 485-489.DOI: 10.7517/issn.1674-0475.211110

• 综述与论文 • 上一篇    下一篇

康柏西普与玻璃体切割联合超声乳化治疗PDR伴白内障的研究

李财保, 江慧敏, 徐婉欣   

  1. 景德镇市第二人民医院眼科, 江西 景德镇 333099
  • 收稿日期:2021-11-04 出版日期:2022-05-15 发布日期:2022-05-27

The Study of Conbercept and Vitrectomy Combined with Phacoemulsification in the Treatment of PDR with Cataract

LI Caibao, JIANG Huimin, XU Wanxin   

  1. Department of Ophthalmology, The Second People's Hospital of Jingdezhen, Jingdezhen 333099, Jiangxi, P. R. China
  • Received:2021-11-04 Online:2022-05-15 Published:2022-05-27

摘要: 本研究探讨增生型糖尿病性视网膜病变(PDR)合并白内障患者采用康柏西普、玻璃体切割术联合超声乳化手术的临床效果。选取120例(120眼)PDR合并白内障患者作为研究对象,采用随机数字表将其分为试验组和对照组,各60例。试验组术后3、6个月时BCVA值小于对照组(P<0.05);术前及术后1、3、6个月时,两组的手术眼散光度比较,差异无统计学意义(P>0.05);试验组在术后1个月的眼压低于对照组(P<0.05);术后1、3、6个月的黄斑中心凹视网膜厚度测定值对比,试验组均低于对照组(P<0.05);试验组前房炎症反应发生率为11.67%,低于对照组的30.00%(P<0.05)。康柏西普、玻璃体切割术联合超声乳化手术较玻璃体切割术联合超声乳化手术治疗PDR合并白内障患者具有更好的改善视力的效果,同时术后患者黄斑中心凹视网膜厚度纠正效果更好,术后前房炎症反应发生率更低。

关键词: 康柏西普, 超声乳化, 白内障, 糖尿病性视网膜病变, 前房炎症反应, 玻璃体切割术

Abstract: This study investigated the clinical effect of conbercept and vitrectomy combined with phacoemulsification in patients with proliferative diabetic retinopathy (PDR) complicated with cataract. Chosen 120 patients (120 eyes) with PDR complicated with cataract as the research objects, and divided them into the experimental group and the control group with 60 cases in each group through random number table. Three and six months after operation the BCVA values of experimental group were both less than those of control group (P<0.05). Preoperative and postoperative 1, 3, 6 months there was no significant difference between the two groups in the astigmatism of the operated eyes (P>0.05). After 1 month operation the intraocular pressure of the experimental group was lower than control group (P<0.05). Compared with the measured values of foveal retinal thickness after 1, 3, 6 months, the experimental group was lower than those of control group (P<0.05). The incidence of anterior chamber inflammation in the experimental group was 11.67% and lower than 30.00% in control group (P<0.05). Conbercept, vitrectomy combined with phacoemulsification have a better visual improvement effect than without conbercept in the treatment of PDR combined with cataract. At the same time the correction effect of the postoperative foveal retinal thickness shows better and the incidence of postoperative anterior chamber inflammation was lower.

Key words: conbercept, phacoemulsification, cataract, diabetic retinopathy, anterior chamber inflammation, vitrectomy