影像科学与光化学 ›› 2022, Vol. 40 ›› Issue (6): 1381-1385.DOI: 10.7517/issn.1674-0475.220702

• 综述与论文 • 上一篇    下一篇

MRI联合血清AFP在诊断CSP及胎盘植入中的应用研究

焦悦, 姚水平, 郭丽, 国春蕾   

  1. 衡水市人民医院产科, 河北 衡水 053000
  • 收稿日期:2022-07-11 出版日期:2022-11-23 发布日期:2022-11-15
  • 通讯作者: 姚水平

Application of MRI Combined with Serum AFP in the Diagnosis of CSP and Placenta Accrete

JIAO Yue, YAO Shuiping, GUO Li, GUO Chunlei   

  1. Department of Obstetrics, Hengshui People's Hospital, Hengshui 053000, Hebei, P. R. China
  • Received:2022-07-11 Online:2022-11-23 Published:2022-11-15

摘要: 本研究探讨磁共振成像(MRI)联合血清甲胎蛋白(AFP)诊断子宫瘢痕妊娠(CSP)及评估胎盘植入的价值。选取73例疑似CSP患者作为CSP组,并选取同期63例正常妊娠者作为正常妊娠组、63例健康非妊娠者作为健康非妊娠组,均行MRI检查,采用放射免疫法检测各组血清AFP检测,对数据资料进行统计分析。结果显示,73例疑似CSP患者,经手术和(或)病理检查证实63例为CSP,MRI检查诊断CSP准确率为95.24%,其中Ⅰ型48例(76.19%),Ⅱ型10例(15.87%),Ⅲ型2例(3.17%),诊断胎盘植入情况准确率为88.24%;血清AFP水平比较,CSP组>正常妊娠组>健康非妊娠组(P<0.05);诊断CSP的AUC为0.784,血清AFP联合MRI诊断CSP的AUC为0.850;胎盘植入患者血清AFP高于非植入患者,血清AFP评估胎盘植入的AUC为0.748,血清AFP联合MRI评估胎盘植入的AUC为0.881。因此,MRI联合血清AFP可作为诊断CSP及胎盘植入一种有效方案。

关键词: 磁共振成像, 甲胎蛋白, 子宫瘢痕妊娠, 胎盘植入

Abstract: This study investigated the value of magnetic resonance imaging (MRI) combined with serum alpha-fetoprotein (AFP) in diagnosing cesarean scar pregnancy (CSP) and evaluating placenta accreta. 73 patients with suspected CSP were selected as the CSP group, 63 normal pregnant women were selected as the normal pregnancy group, and 63 healthy non-pregnant patients were selected as the healthy non-pregnant group. MRI examination was performed, serum AFP was detected by radioimmunoassay, and the data were analyzed statistically. The results showed that among 73 patients with suspected CSP, 63 were confirmed to be CSP by surgery and/or pathological examination. The accuracy rate of MRI diagnosis of CSP was 95.24%, of which 48 were type Ⅰ (76.19%), and 10 cases type Ⅱ (15.87%), 2 cases of type Ⅲ (3.17%), the accuracy rate of diagnosing placenta accreta was 88.24%. Comparison of serum AFP levels, CSP group > normal pregnancy group > healthy non-pregnant group (P<0.05). The AUC for the diagnosis of CSP was 0.784, and the AUC of serum AFP combined with MRI for the diagnosis of CSP was 0.850. The serum AFP of patients with placenta accreta was higher than that of non-accreta patients. The AUC of serum AFP to evaluate placenta accreta was 0.748, and the AUC of serum AFP combined with MRI to evaluate placenta accreta was 0.881. Therefore, MRI combined with serum AFP can be an effective solution for the diagnosis of CSP and placenta accreta.

Key words: magnetic resonance imaging, alpha-fetoprotein, cesarean scar pregnancy, placenta accreta