数字全息显微在医学影像中的发展与最新应用

doi:10.7517/j.issn.1674-0475.2016.01.023

影像科学与光化学 ›› 2016, Vol. 34 ›› Issue (1): 23-29.DOI: 10.7517/j.issn.1674-0475.2016.01.023

数字全息显微在医学影像中的发展与最新应用

吴育民^1,2, 宋国庆^1,2, 冯云鹏^1,2, 王钟³

1. 北京理工大学光电学院光机电联合研究中心, 北京 100081;
2. 北京理工大学深圳研究院, 广东深圳 518057;
3. 深圳市博瑞汇达科技有限公司, 广东深圳 518057

收稿日期:2015-10-23 修回日期:2015-11-04 出版日期:2016-01-15 发布日期:2016-01-15
通讯作者: 冯云鹏
基金资助:
国家自然科学基金项目(61308075)和北京市自然科学基金项目(2132047,4144083)资助

Development and Application of Digital Holographic Microscopy in Biomedicine

WU Yumin^1,2, SONG Guoqing^1,2, FENG Yunpeng^1,2, WANG Zhong³

1. Joint Research Center for Optomechatronics Engineering, School of Optoelectronics, Beijing Institute of Technology, Beijing 100081, P. R. China;
2. Shenzhen Research Institute, Beijing Institute of Technology, Shenzhen 518057, Guangdong, P. R. China;
3. Boruihuida Science and Technology Ltd. Co., Shenzhen 518057, Guangdong, P. R. China

Received:2015-10-23 Revised:2015-11-04 Online:2016-01-15 Published:2016-01-15

摘要/Abstract

摘要：

随着CCD等光电成像器件和计算机技术的迅猛发展,数字全息显微技术不断发展成熟起来,以其非接触、定量、三维成像等特点广泛应用于医学影像领域。本文综述了数字全息显微技术在生物医学方面的发展;比较了数字全息显微技术与其它显微技术在生物医学成像方面的优缺点;分析总结了不同全息显微影像信息系统;论述了不同光源结构对数字全息显微成像效果的重要影响以及相应算法补偿;列举了数字全息显微在生物医学中的最新应用。

关键词: 数字全息, 影像处理, 生物医学, 显微成像

Abstract:

In recent years, with the rapid development of optoelectronic imaging devices such as CCD and computer technology, digital holographic microscopy technology has been developed, which has been widely used in the field of biomedicine with the characteristics of no-contact, quantitative, three-dimensional imaging.The development of digital holographic microscopy is reviewed.The advantages and disadvantages of digital holographic microscopy and other techniques are compared.From the point of view of light source, the important influence of different light source on digital holographic microscopy imaging and the corresponding algorithm are discussed.The latest applications of digital holographic microscopy in biomedicine are enumerated.

Key words: digital holography, image processing, biomedicine, microscopic imaging

吴育民, 宋国庆, 冯云鹏, 王钟. 数字全息显微在医学影像中的发展与最新应用[J]. 影像科学与光化学, 2016, 34(1): 23-29.

WU Yumin, SONG Guoqing, FENG Yunpeng, WANG Zhong. Development and Application of Digital Holographic Microscopy in Biomedicine[J]. Imaging Science and Photochemistry, 2016, 34(1): 23-29.

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数字全息显微在医学影像中的发展与最新应用

Development and Application of Digital Holographic Microscopy in Biomedicine

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