影像科学与光化学 ›› 2020, Vol. 38 ›› Issue (1): 22-26.DOI: 10.7517/issn.1674-0475.190612

• 综述与论文 • 上一篇    下一篇

甲基丙烯酰胺基明胶水凝胶研究进展

王毅虎1,2, 曹霄峰1, 张兵1, 王佳宁1,2, 张炜杰1, 郭燕川1   

  1. 1. 中国科学院 理化技术研究所 化学转化与功能材料重点实验室, 北京 100190;
    2. 中国科学院大学, 北京 100049
  • 收稿日期:2019-06-24 出版日期:2020-01-15 发布日期:2020-01-15

The Research Progress of Methacrylamide Gelatin Hydrogel

WANG Yihu1,2, CAO Xiaofeng1, ZHANG Bing1, WANG Jianing1,2, ZHANG Weijie1, GUO Yanchuan1   

  1. 1. Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, CAS, Beijing 100190, P. R. China;
    2. University of Chinsese Academy of Sciences, Beijing 100049, P. R. China
  • Received:2019-06-24 Online:2020-01-15 Published:2020-01-15

摘要: 甲基丙烯酰胺基明胶(GelMA)水凝胶的制备及其在生物医学领域的应用是最近十几年的研究热点。GelMA水凝胶因其独特的光致交联特性,可以加工成不同形貌的水凝胶支架材料,同时,因其具有可控的力学性能、降解性能,以及优秀的生物相容性,已成为具有广泛应用前景的生物高分子聚合物材料。本文主要介绍了GelMA水凝胶在止血材料、创伤敷料、组织工程支架、药物控释、骨缺损修复等领域的研究进展。

关键词: 甲基丙烯酰胺基明胶, 水凝胶, 生物医用材料, 组织工程

Abstract: The preparation of methacrylamide gelatin (GelMA) hydrogel and its application in biomedicine is a research hotspot in the past decade. Due to its unique photocrosslinking properties, GelMA hydrogel can be processed into hydrogel scaffolds with different morphologies, with controlled mechanical properties and degradation properties, and excellent biocompatibility, making them a biopolymer material with broad application prospects. This paper mainly introduces the research progress of GelMA hydrogel in the fields of hemostatic materials, wound dressings, tissue engineering scaffolds, drug release, and bone defect repair.

Key words: methacrylamide gelatin, hydrogel, biomedical materials, tissue engineering