声脉冲辐射力弹性成像对宫颈癌同步放化疗疗效的早期预测价值

doi:10.7517/issn.1674-0475.191004

摘要/Abstract

摘要： 为探讨声脉冲辐射力弹性成像技术对宫颈癌同步放化疗疗效的早期预测价值，本研究选取2018年1月~2019年6月我院经病理检查确诊的宫颈癌患者57例，所有患者均给予同步放化疗方案治疗。采用GE LOGIQ E9彩色多普勒超声诊断仪分别在治疗前、治疗2周后和治疗结束时，对患者进行常规超声和超声弹性成像检查，测量并记录弹性图像评分、应变比值及剪切波速度。结果显示，经同步放化疗治疗后，66.67%的患者完全缓解（CR）（38/57），33.33%的患者部分缓解（PR）（19/57），无进展和稳定患者。治疗前，CR组与PR组患者病灶弹性图像评分和剪切波速度比较，差异均有统计学意义（P<0.05），弹性应变比值比较，差异无统计学意义（P>0.05）。随着治疗的进展，CR组与PR组患者病灶弹性图像评分、弹性应变比值及剪切波速度均逐渐下降，治疗2周后和治疗结束时，两组患者病灶弹性图像评分、弹性应变比值及剪切波速度均低于治疗前，且CR组低于PR组，差异均有统计学意义（P<0.05）。因此，通过声脉冲辐射力弹性成像技术早期持续监测病灶弹性图像评分、弹性应变比值、剪切波速度变化来反映宫颈癌同步放化疗效果，对宫颈癌同步放化疗疗效具有一定的早期预测价值。

关键词: 宫颈癌, 同步放化疗, 声脉冲辐射力弹性成像, 弹性应变比值, 剪切波速度

Abstract: To investigate the early predictive value of acoustic radiation force impulse imaging (ARFI) technique in concurrent radiotherapy and chemotherapy for cervical cancer, in this study, 57 patients with cervical cancer diagnosed by pathological examination in our hospital from January 2018 to June 2019 were selected. All patients were treated with concurrent radiotherapy and chemotherapy. Before treatment, 2 weeks after treatment and at the end of treatment, the patients were examined with GE LOGIQ E9 color Doppler ultrasound diagnostic instrument. The elastic image score, strain ratio and shear wave velocity were measured and recorded. The results showed that, After concurrent chemoradiotherapy, 66.67% patients had complete remission (CR) (38/57), 33.33% patients had partial remission (PR) (19/57), no progress and stable patient. Before treatment, there were significant differences in elastic image score and shear wave velocity between CR group and PR group (P<0.05), there was no significant difference in elastic strain ratio between CR group and PR group (P>0.05). With the progress of treatment, the elastic image score,strain ratio and shear wave velocity of lesions in CR group and PR group decreased gradually. After 2 weeks of treatment and at the end of treatment, the elastic image score, strain ratio and shear wave velocity of lesions in CR group and PR group were lower than those before treatment, and CR group was lower than PR group, the difference was statistically significant (P<0.05). According to this, the elastic image score, strain ratio and shear wave velocity were continuously monitored by ARFI technique in the early stage, to reflect the effect of concurrent radiotherapy and chemotherapy for cervical cancer, it has a certain early predictive value for the efficacy of concurrent radiotherapy and chemotherapy for cervical cancer.

Key words: cervical cancer, concurrent radiotherapy and chemotherapy, acoustic radiation force impulse imaging, strain ratio, shear wave velocity

中图分类号:

武杰. 声脉冲辐射力弹性成像对宫颈癌同步放化疗疗效的早期预测价值[J]. 影像科学与光化学, 2020, 38(2): 350-355.

WU Jie. Early Predictive Value of Acoustic Radiation Force Impulse Imaging in Concurrent Radiotherapy and Chemotherapy for Cervical Cancer[J]. Imaging Science and Photochemistry, 2020, 38(2): 350-355.

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