头颅CT和MRI诊断高胆红素血症患儿脑损伤的效果对比分析

doi:10.7517/issn.1674-0475.191019

摘要/Abstract

摘要： 为了分析头颅CT和磁共振成像（MRI）在诊断高胆红素血症患儿脑损伤中的效果，本研究选取了50例高胆红素血症患儿为研究对象，根据脑干听觉诱发电位（BAEP）检测结果，将其分为BAEP正常组（24例）和BAEP异常组（26例）；同时选取25例产科健康足月新生儿为对照组，比较三组患儿血清胆红素（TB）水平和行为神经测定评分（NBNA）。高胆红素血症患儿行头颅CT和MRI检测，以BAEP为金标准，分析CT、MRI以及两者联合检测诊断高胆红素血症患儿脑损伤的效果。结果显示，BAEP正常组和BAEP异常组的TB水平均显著高于对照组，NBNA评分均显著低于对照组，且BAEP异常组TB水平显著高于BAEP正常组，NBNA评分显著低于BAEP正常组。由此可知，MRI诊断高胆红素血症的灵敏度和准确度均高于CT，两者联合检测可提高诊断的特异度和准确度，降低误诊率。

关键词: 高胆红素血症, CT, MRI, 脑损伤

Abstract: In order to analyze the effects of cranial CT and magnetic resonance imaging (MRI) in the diagnosis of brain damage in children with hyperbilirubinemia, 50 children with hyperbilirubinemia were selected as subjects. According to the results of brainstem auditory evoked potential (BAEP), they were divided into normal group (24 cases) and abnormal group (26 cases). 25 healthy full-term neonates were chosen as the control group. Serum bilirubin (TB) levels and behavioral neurological scores (NBNA) were compared among the three groups. Head CT and MRI were performed in children with hyperbilirubinemia. BAEP was used as the gold standard to analyze the clinical effects of CT, MRI and the combination of the two in the diagnosis of brain damage in children with hyperbilirubinemia. The results showed that the TB level in the BAEP normal group and the BAEP abnormal group was significantly higher than that in the control group, and the NBNA score was significantly lower than that in the control group, and the TB level of BAEP abnormal group was significantly higher than that of the BAEP normal group, and the NBNA score was significantly lower than that of the BAEP normal group. The sensitivity and accuracy of MRI in the diagnosis of hyperbilirubinemia is higher than that of CT. The combined detection can improve the specificity and accuracy of diagnosis and reduce the rate of misdiagnosis.

Key words: hyperbilirubinemia, CT, MRI, brain injury

李娟, 刘晓侠, 王栋, 李剑, 蔡娅. 头颅CT和MRI诊断高胆红素血症患儿脑损伤的效果对比分析[J]. 影像科学与光化学, 2020, 38(3): 453-458.

LI Juan, LIU Xiaoxia, WANG Dong, LI Jian, CAI Ya. Comparative Analysis of Brain CT and MRI in the Diagnosis of Brain Damage in Children with Hyperbilirubinemia[J]. Imaging Science and Photochemistry, 2020, 38(3): 453-458.

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