Imaging Science and Photochemistry ›› 2020, Vol. 38 ›› Issue (5): 929-933.DOI: 10.7517/issn.1674-0475.200328

• Review and Articles • Previous Articles    

Comparative Study of Whole Body Diffusion Weighted Imaging and CT in Evaluating the Efficacy of Chemotherapy for Lymphoma

LIU Yongxin, LI Linlin, MA Jing   

  1. Emergency Department, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei, P. R. China
  • Received:2020-03-25 Online:2020-09-15 Published:2020-09-15

Abstract: The purpose of this study was to compare the effect of whole body diffusion weighted imaging (WB-DWI) with that of computed tomography (CT) in evaluating the efficacy of chemotherapy for lymphoma.60 patients with lymphoma were selected as the case group and 43 healthy volunteers were selected as the control group. The results showed that the lymph nodes in the lesion showed significantly high signal in WB-DWI and CT examination. After 1, 4 and 8 cycles of chemotherapy, the signal intensity on the images of WB-DWI and CT was significantly lower than that before chemotherapy, and the coincidence rate of WB-DWI in the lesion size, lesion range and number of lesions were significantly higher than that of CT examination (P<0.05).ADC values and the average ADC values of each site in the case group were lower than those of the control group (P<0.05). There were statistically significant differences in ADC values before and after treatment, before and during chemotherapy, and after chemotherapy in the case group (P<0.05). In general, WB-DWI is better than CT in evaluating the efficacy of chemotherapy in lymphoma, which is worthy of clinical application.

Key words: magnetic resonance whole body diffusion weighted imaging, computed tomography, lymphoma, chemotherapy, curative effect evaluation