IMAGING SCIENCE AND PHOTOCHEMISTRY ›› 2021, Vol. 39 ›› Issue (5): 700-704.DOI: 10.7517/issn.1674-0475.210211

• Review and Articles • Previous Articles     Next Articles

The Value of MSCT Three-dimensional Reconstruction Combined with Serum NSE and SCC-Ag in the Diagnosis of the Nature of Small Pulmonary Nodules

HOU Qing1, WANG Xin2, YANG Huijuan3   

  1. 1. Radiology Department, Beijing Puren Hospital, Beijing 100062, P. R. China;
    2. Radiology Department, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, P. R. China;
    3. Clinical Laboratory, Beijing Puren Hospital, Beijing 100062, P. R. China
  • Received:2021-02-26 Published:2021-09-13

Abstract: This article discusses the value of multi-slice spiral CT (MSCT) three-dimensional reconstruction combined with serum neuron specific enolase (NSE) and squamous cancinoma-associated antigen (SCC-Ag) in the diagnosis of lung malignant nodules. A total of 113 patients with malignant pulmonary nodules diagnosed pathologically after surgery were selected as the malignant group, and 100 patients with benign pulmonary nodules were selected as the benign group. The MSCT three-dimensional reconstruction characteristics, serum NSE and SCC-Ag levels of the two groups were compared, and three were calculated. The value of the method alone or in combination in the diagnosis of malignant pulmonary nodules. The results showed that the detection rate of nodule lobules, outer edge burr, pleural depression, and vascular clustering signs in the malignant group was higher than that in the benign group (P<0.05); the serum NSE and SCC-Ag levels in the malignant group were higher than those in the benign group Patients (P<0.05). The sensitivity of the combined application of serum NSE, SCC-Ag, and MSCT three-dimensional reconstruction in differential diagnosis of pulmonary benign and malignant nodules was 95.58%, and the specificity was 86.00%. It shows that the combined application of the three-dimensional reconstruction features of MSCT, serum NSE, and SCC-Ag has high sensitivity and specificity in the diagnosis and differentiation of small pulmonary nodules.

Key words: multi-slice spiral CT, three-dimensional reconstruction, neuron specific enolase, squamous cancinoma-associated antigen, pulmonary nodule