SMI Evaluation of IPN Formation and Risk Factors for ACI in Carotid Plaques

doi:10.7517/issn.1674-0475.220401

Abstract

Abstract: This study investigated the value of ultramicroscopic flow imaging (SMI) in evaluating the formation of neovascularization (IPN) in carotid atherosclerotic plaques and in predicting the occurrence of acute cerebral infarction (ACI). 60 patients with ACI with carotid atherosclerotic plaque were set as the ACI group and 60 patients with carotid plaque without ACI set as the control group. Both of the two groups underwent SMI, ultrasound angiography (CEUS) examination, and compared the grading of neovascularization in the carotid plaque detected by SMI and CEUS in the two groups, and the multivariate Logistic model was used to analyze the relationship between the formation of IPN in the plaque and the occurrence of ACI. A total of 120 carotid plaques were detected in 60 ACI patients. The consistency test value of SMI and CEUS in diagnosing IPN formation in carotid plaques was Kappa=0.723, P=0.000. A total of 127 carotid plaques were detected in the control group, and the concordance Kappa value of SMI and CEUS in diagnosing IPN formation in carotid plaques was 0.537, P=0.000. The serum TG, LDL-C elevation, concomitant diabetes mellitus, concomitant hypertension, and IPN formation in carotid plaques were the independent risk factors for ACI patients (P<0.05). SMI is highly consistent with CEUS in evaluating carotid atherosclerotic plaque IPN formation, and carotid plaque IPN formation is highly correlated with the occurrence of ACI in patients.

Key words: ultramicroscopic blood flow imaging, carotid atherosclerotic plaque, neovascularization, prediction, Acute cerebral infarct

WANG Wenfeng, CHANG Ye, MOU Rongji. SMI Evaluation of IPN Formation and Risk Factors for ACI in Carotid Plaques[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2022, 40(5): 1299-1303.

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