IMAGING SCIENCE AND PHOTOCHEMISTRY ›› 2022, Vol. 40 ›› Issue (5): 1169-1173.DOI: 10.7517/issn.1674-0475.220408

• Review and Articles • Previous Articles     Next Articles

Fungal Ball Sinusitis: CT Characteristics and Relationship with Serum BMP-2 and EGF

ZHAO Xingquan1, ZHONG Qu1, GAO Lijun2, GU Shanshan2, LI Jia1, CHEN Qian1   

  1. 1. Department of Otorhinolaryngology, Sichuan Mianyang 404 Hospital, Mianyang 621000, Sichuan, P. R. China;
    2. Department of Imaging, The Second Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan, P. R. China
  • Received:2022-04-26 Published:2022-09-13

Abstract: This study investigated the CT image characteristics of fungal glomus sinusitis and its relationship with the expression of serum bone morphogenetic protein-2 (BMP-2) and epidermal growth factor (EGF). 106 patients with fungal glomus sinusitis were selected as the observation group, and 100 healthy people were selected as the control group. All patients underwent the CT examination, and examined the serum BMP-2 and EGF expression levels. The proportion of nasal septum deviation, moderate and severe deviation, high deviation in the observation group were higher than those in the control group (P<0.05), the proportions of turbinate gasification, uncinate process deviation, uncinate process hypertrophy and Haller's air chamber in the observation group were higher than those in the control group (P<0.05). Serum BMP-2 and EGF in the observation group were significantly higher than those in the control group (P<0.05). The levels of serum BMP-2 and EGF in patients with nasal septum deviation and middle turbinate gasification in the observation group were higher (P<0.05). The incidence of structural variation such as deviation of nasal septum and gasification of middle turbinate increased in patients with fungal sinusitis, and the levels of serum BMP-2 and EGF were related to deviation of nasal septum and gasification of middle turbinate.

Key words: fungal glomus sinusitis, deviation of nasal septum, middle turbinate gasification, bone morphogenetic protein-2, epidermal growth factor