IMAGING SCIENCE AND PHOTOCHEMISTRY ›› 2022, Vol. 40 ›› Issue (5): 1056-1061.DOI: 10.7517/issn.1674-0475.220518

• Review and Articles • Previous Articles     Next Articles

Effect of MSCT Combined with ERCP on Postoperative Infection in Patients with Duodenal Diverticulum Complicated with Gallstones

LU Meng1, CUI Leilei2, JIANG Lijie2, KANG Jie2   

  1. 1. The Department of Infection Control, Hengshui People's Hospital, Hengshui 053000, Hebei, P. R. China;
    2. Imaging Center, Hengshui People's Hospital, Hengshui 053000, Hebei, P. R. China
  • Received:2022-05-27 Published:2022-09-13

Abstract: This study investigated the effect of multilayer spiral CT (MSCT)-based, endoscopic retrograde cholangiopancreatography (ERCP) observation on postoperative infection control in patients with duodenal diverticulum combined with gallstones. 210 patients with duodenal diverticulum combined with gallstones were selected and randomly divided into study group and control group with 105 cases in each group. The control group performed ERCP endoscopic lithotripsy, and the study group performed MSCT and ERCP-based endoscopic lithotripsy. The results showed that the success rate of ERCP cannulation in the study group was higher than those in the control group, and the operation time, nasobiliary drainage time and postoperative hospitalization time were shorter than those in the control group (P<0.05). The serum C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), blood glucose (Glu), cortisol (Cor) levels at 1 d and 3 d after surgery were lower than those before surgery in both groups, but they were all lower in the study group than in the control group (P<0.05). The serum CD3+ and CD4+ levels at 1 d and 3 d after surgery were lower than those before surgery in both groups, but they were all higher in the study group than in the control group (P<0.05). The serum CD8+ levels at 1 d after surgery were lower than those before surgery in both groups (P<0.05). The incidence of incisional infection, biliary tract infection and recurrence rate at 6 months and 1 year after surgery in the study group were lower than in the control group (P<0.05). It can be seen that endoscopic lithotripsy based on MSCT and ERCP observation can reduce the incidence of postoperative infection and effectively reduce postoperative recurrence in patients with duodenal diverticulum combined with gallstones.

Key words: gallstones, duodenal diverticulum, endoscopic retrograde cholangiopancreatography, multilayer spiral CT, infection