IMAGING SCIENCE AND PHOTOCHEMISTRY ›› 2022, Vol. 40 ›› Issue (5): 1253-1257.DOI: 10.7517/issn.1674-0475.220528

• Review and Articles • Previous Articles     Next Articles

Application of MSCT Combined with Serum Immune Inflammatory Factors in the Diagnosis of Fracture Nonunion

LIU Lufeng1, WANG Meng2   

  1. 1. Department of Physical Education, Northwest University of Political Science and Law, Xi'an 710100, Shaanxi, P. R. China;
    2. The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi, P. R. China
  • Received:2022-05-30 Published:2022-09-13

Abstract: This paper investigated the multilayer spiral CT imaging (MSCT) in the diagnosis of fractures after knee injury and its correlation with serum immune inflammatory factor levels. 82 gymnasts with suspected post-knee injury fractures were selected for the study, and all patients underwent X-ray, MSCT examination, and serum immune inflammatory factor testing. Compared the differences of quantitative parameters of MSCT[bone mineral density (BMD), cross-sectional moment of inertia mechanical strength index (BSICSMI), cross-sectional area mechanical strength index (BSICSA)] and the serum immune inflammatory factors[tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), IL-1β] between fracture healed and non-healed patients, and analyzed the correlation between the quantitative parameters of MSCT and serum immune inflammatory factors, and evaluated the value of MSCT quantitative parameters and serum immune inflammatory factors in evaluating fracture non-union. The concordance Kappa value between the type of fracture and surgical outcome after the diagnosis of knee injury by MSCT was 0.901, and the compliance rate was 92.68%. BMD, BSICSA, and BSICSMI in patients with fracture healing were higher than in patients with fracture non-union, and serum TNF-α, IL-6, and IL-1β levels were lower than those in patients with unhealed fractures (P<0.05). After knee injury the BMD, BSICSA, and BSICSMI were negatively correlated with serum TNF-α, IL-6, and IL-1β levels in patients with fractures (P<0.05). The AUC of the combined assessment of quantitative parameters of MSCT and serum immune inflammatory factors for fracture nonunion was 0.908, and was better than evaluating each indicator individually. The effectiveness of MSCT in diagnosing fracture after knee injury was higher, and the quantitative CT parameters were correlated with serum immune inflammatory factors, so MSCT combined with serum immune inflammatory factors could effectively diagnose fracture nonunion.

Key words: multilayer spiral CT imaging, gymnast, knee injury, fracture, immune inflammatory factor