Imaging Science and Photochemistry ›› 2018, Vol. 36 ›› Issue (1): 57-63.DOI: 10.7517/j.issn.1674-0475.2018.01.005

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Biomimetic Synthesis of CdS Quantum Dots in Living Cancer Cells

JI Haixia1,2, DONG Lulu1,2, DU Yan1,2, YAO Xinyue1,2, YANG Dongzhi1,2   

  1. 1. Department of Pharmaceutical Analysis, Xuzhou Medical University, Xuzhou 221004, Jiangsu, P. R. China;
    2. Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, P. R. China
  • Received:2017-02-21 Revised:2017-05-02 Online:2018-01-15 Published:2018-01-15

Abstract: With the cervical cancer cells, HeLa, as the carrier, glutathione in living cancer cells as the modifier and stabilizer, CdS quantum dots was synthesized during the normal cells life metabolic process. The optical spectra showed that the prepared CdS quantum dots emitted at about 450 nm with the quantum yield of 5.2%. The structure characteristics by transmission electron microscopy (TEM) and X-ray powder diffraction (XRD) showed that the particles size of the prepared CdS quantum dots was about 3.0 nm with cubic crystal structure.

Key words: biomimetic synthesis, cadmium sulfide, cancer cells, glutathione