Preparation and Photostability of the Inclusion Complex of HP-β-CD with Piceid

doi:10.7517/j.issn.1674-0475.2015.06.487

Abstract

Abstract:

The inclusion complex between piceid and (2-hydroxy)propyl-β-cyclodextrin (HP-β-CD) was prepared by freeze-drying method. The effects of the inclusion behavior of piceid with HP-β-CD was investigated by methods of phase-solubility, X-ray diffraction (XRD), thermogravimetric analysis (TG), differential scanning calorimetry (DSC), and scanning electron microscopy (SEM). Meanwhile, the photostability of piceid and its inclusion complex was also investigated. The results showed that piceid formed 1:1 stoichiometric inclusion complex with HP-β-CD, and the apparent stability constant was 1308 mol^-1·L. The solubility of the piceid was enhanced more than 10 times. Also the decomposition temperature of piceid was improved from 270 ℃ to 298 ℃ after encapsulated by HP-β-CD. Furthermore, the photostability of the inclusion complex was more stable than the native piceid. Therefore, it can be a potentially promising way to promote its food supplement or cosmetic preparations.

Key words: piceid, cyclodextrin, inclusion complex, solubility, photostability

LI Shujing, ZHOU Ziruo, YUE Junzhi, ZHOU Wei, WANG Xinrui, BAI Dongsheng. Preparation and Photostability of the Inclusion Complex of HP-β-CD with Piceid[J]. Imaging Science and Photochemistry, 2015, 33(6): 487-493.

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