A Highly Selective Mercury Ion (Ⅱ) Fluorescent Probe Based on Dansyl Dye

doi:10.7517/j.issn.1674-0475.2017.03.297

Abstract

Abstract:

Mercury ion (Ⅱ) is known as one of the most toxic metal ions both for humans and the environment. In this work, a new fluorescent probe based on dansyl dye was designed and synthesized, and its determining property towards metal cations was investigated. The result indicated that this dansyl-based fluorescent probe possessed high selectivity and good sensitivity towards mercury ion (Ⅱ) in an aqueous media without any interference from other metal cations. It was worth mentioning that the detection limit of mercury ion (Ⅱ) can reach to 2.1×10^-8 mol/L. Such low detection limit and good water-solubility supported this probe could be used to visualize the level of mercury ion (Ⅱ) in living cells. Furthermore, the bioimaging experiment confirmed that this probe had good membrane permeability and biocompatibility.

Key words: dansyl dye, mercury ion (Ⅱ) detection, fluorescent probe, bioimaging

HU Linli, ZHANG Yufeng, ZHANG Xin, YIN Jun. A Highly Selective Mercury Ion (Ⅱ) Fluorescent Probe Based on Dansyl Dye[J]. Imaging Science and Photochemistry, 2017, 35(3): 297-306.

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