Imaging Science and Photochemistry ›› 2017, Vol. 35 ›› Issue (3): 316-321.DOI: 10.7517/j.issn.1674-0475.2017.03.316

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The Application of Fluorescence Molecular Probe in Saccharin Sodium Determination

CAO Zhanqi1, LIU Xinyuan2, QU Dahui1   

  1. 1. Key Laboratory for Advanced Materials and Institute of Fine Chemicals, School of Chemistry and Molecular Engineering, East China University of Science & Technology, Shanghai 200237, P.R. China;
    2. Nanyang Model School, Shanghai 200032, P.R. China
  • Received:2017-02-15 Revised:2017-03-21 Online:2017-05-15 Published:2017-05-15

Abstract:

With the development of technology and the progress of society, the food safety problem gains increasing attention. Saccharin sodium, as one kind of food additives, is occasionally reported as illegal additions. Thus it is necessary to find a rapid and accurate method for the detection of saccharin sodium. The fluorescence molecular probe has gained a widely application in analytical chemistry determination due to its advantages such as high sensitivity, good selectivity and short response time. In this paper, a novel compound contained an anthracene fluorophore and an aza-15-crown-5 group was designed and synthesized. Based on the molecular recognition, the compound could specifically recognize the saccharin sodium in solution, resulting in the changes of fluorescence intensity.What's more,the phenomenon is visible and easy to be observed. The method provides a practicable strategy for rapid determination saccharin sodium in food.

Key words: saccharin sodium, fluorescence molecular probe, molecular recognition, specific recognition