Photochemical Biology of Nucleic Acids

doi:10.7517/j.issn.1674-0475.2017.04.010

Abstract

Abstract:

Caging groups for the photochemical trigger have been widely used in photoregulation of many biological processes. In the past decade, different caging strategies on nucleotides,oligonucleotides and DNA/RNA have been developed, and have been applied in many biological research, such as cellular signal transduction and target gene regulation. This review mainly focused on commonly used caging groups and their recent progress in caged nucleic acids and their applications in chemical biology, and also proposed future development in photochemical biology of nucleic acids.

Key words: photochemical biology, caging group, nucleotide, nucleic acid

ZHANG Xueli, TANG Xinjing. Photochemical Biology of Nucleic Acids[J]. Imaging Science and Photochemistry, 2017, 35(4): 477-493.

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