Site-specific Modification of Tobacco Mosaic Virus and Its Applications

doi:10.7517/j.issn.1674-0475.2017.04.011

Abstract

Abstract:

Viruses behave the simplest structure yet a high transfection efficiency in nature. As a classic 1-dimensional rod-like plant virus, tobacco mosaic virus (TMV) has the monodispersed morphology and size (18 nm × 300 nm), well-defined spatial structure, abundant chemical groups on surfaces, and non-infection to mammals. Thus, TMV has received great research interest in electronic devices, sensing, imaging and biomedicine. In this review, we will introduce the gene and chemical modifications for TMV and its potential applications, especially in the field of biomedical materials.

Key words: tobacco mosaic virus, gene engineering, chemical modification, biomedical materials

TIAN Ye, ZHU Meng, NIU Zhongwei. Site-specific Modification of Tobacco Mosaic Virus and Its Applications[J]. Imaging Science and Photochemistry, 2017, 35(4): 494-505.

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