Imaging Science and Photochemistry ›› 2019, Vol. 37 ›› Issue (2): 163-168.DOI: 10.7517/issn.1674-0475.181001

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Efficacy and Feasibility Analysis of Ultrasound-guided Paravertebral Nerve Block for the Treatment of Post-herpetic Neuralgia

ZHANG Yanru1, FENG Weizheng1, SHAO Huiying2, LIU Shoufang1, DUAN Changling1, ZHAO Jiamin1   

  1. 1. Jiading Nanxiang Hospital, Shanghai 201802, P. R. China;
    2. Children's Hospital of Fudan University, Shanghai 201102, P. R. China
  • Received:2018-09-30 Revised:2018-11-28 Online:2019-03-15 Published:2019-03-15

Abstract: To analysis the efficacy and feasibility of ultrasound-guided paravertebral nerve block for the treatment of post-herpetic neuralgia, ninety-four patients with PHN admitted to our hospital from December 2015 to December 2017 were selected as the study subjects. They were randomly divided into two groups according to the order of treatment. The control group received routine treatment with pregabalin, and the observation group combined routine treatment with ultrasound-guided paravertebral nerve block therapy for 4 weeks. Pittsburgh sleep quality index (PSQI) scores and pain visual analogue (VAS) scores before treatment, 1 week, 2 weeks, and 4 weeks of treatment were compared. The combined efficacy after treatment was evaluated, and the adverse reactions during treatment were recorded. The results showed that compared with pre-treatment, the VAS scores of the two groups were gradually decreased at 1 week, 2 weeks, and 4 weeks of treatment, and the observation group was significantly lower than the control group at each time point after treatment, the difference was statistically significant (P<0.05). The PSQI scores of the two groups were gradually decreased at 1 week, 2 weeks, and 4 weeks of treatment, and the observation group was significantly lower than the control group at each time point after treatment, the difference was statistically significant (P<0.05). The total effective rate was 89.36% in the observation group and 78.72% in the control group, and the difference was statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Ultrasound-guided paravertebral nerve block for PHN can significantly reduce neuropathic pain in patients, improve sleep quality, and has security guarantee.

Key words: ultrasound-guided paravertebral nerve block, pregabalin, post-herpetic neuralgia