Imaging Science and Photochemistry ›› 2019, Vol. 37 ›› Issue (4): 324-331.DOI: 10.7517/issn.1674-0475.190302

• Review and Articles • Previous Articles     Next Articles

The Applications of Zeiss Axio Scan.Z1 Automatic Digital Slide Scanning System

YIN Wei1, LIU Shuangshuang1, ZHENG Yanrong2, ZHANG Xiangnan2   

  1. 1. The Core Facilities, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310058, Zhejiang, P. R. China;
    2. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, Zhejiang, P. R. China
  • Received:2019-03-27 Online:2019-07-15 Published:2019-07-15

Abstract: The full-automatic slice scanning technology has great advantages and wide application scope, and gradually becomes a revolutionary auxiliary means for morphological and pathological research. In this paper, the configuration parameters (optical system, objective lens, resolution, scanning speed, camera, etc.) and imaging characteristics of Zeiss Axio Scan.Z1 slice scanning system are introduced, and the important applications of Zeiss Axio Scan.Z1 in large-scale whole tissue scanning, histopathology, neurobiology and other research fields are expounded. This paper summarizes the problems encountered during the use of the instrument, analyzes the possible causes, and puts forward the solutions to ensure that the instrument provides better sharing services for scientific research.

Key words: full-automatic slice scanning technology, Zeiss Axio Scan.Z1, large-scale whole tissue scanning