Imaging Science and Photochemistry ›› 2019, Vol. 37 ›› Issue (6): 564-570.DOI: 10.7517/issn.1674-0475.190508

• Review and Articles • Previous Articles     Next Articles

The Radiation and Contrast Agent Dosage Selection of Multi-slice Spiral CT in the Diagnosis of Thyroid Cancer

LI Yuan, CHEN Shixin, HUANG Bin   

  1. Imaging Department, Hanzhong 3201 Hospital, Hanzhong 723000, Shaanxi, P. R. China
  • Received:2019-05-09 Online:2019-11-15 Published:2019-11-15

Abstract: To discuss the radiation and contrast agent dosage selection of multi-slice spiral CT (MSCT) in the diagnosis of thyroid cancer, 200 patients with thyroid cancer or benign thyroid nodules underwent MSCT examination were selected as the subjects of this study from December 2016 to December 2018 in our hospital. They were divided into group A, group B, group C and group D, 50 cases in each group. The parameters of group A were 1.2 mL/kg of contrast agent, 120 kV and 180 mA, group B was 1.0 mL/kg of contrast agent, 120 kV and 180 mA, group C was 1.2 mL/kg of contrast agent, 100 kV and 100 mA, group D was 1.0 mL/kg of contrast agent, 100 kV, 100 mA. The results showed that, the CT volume dose index (CTDIvol), dose length product (DLP), effective radiation dose (ED) in group A and group B were significantly lower than those in group C and group D, the thyroid CT value, background signal, background noise in group A and group B were significantly higher than those in group C and group D, the difference was statistically significant (P<0.05), and there was no significant difference in SNR, CNR and image quality score between group A, group B, group C and group D (P>0.05). There was no significant difference in sensitivity, specificity and accuracy of thyroid cancer diagnosis between group A, group B, group C and group D (P>0.05). This study confirms that, in the radiation and contrast agent dosage selection of MSCT in the diagnosis of thyroid cancer, the 1.0 mL/kg, 100 kV and 100 mA can effectively reduce the CT radiation of patients without seriously affecting the image quality and examination results. It is worth for further clinical promotion.

Key words: multi-slice spiral CT, diagnosis, thyroid cancer, radiation, contrast agent, dosage selection