Imaging Science and Photochemistry ›› 2020, Vol. 38 ›› Issue (1): 125-131.DOI: 10.7517/issn.1674-0475.190806

• Review and Articles • Previous Articles     Next Articles

Resting Brain Functional Magnetic Resonance Imaging of Post-stroke Epilepsy

MIAO Yanping, ZHAO Sheng   

  1. Department of Imaging Diagnostics, the Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, Inner Mongolia, P. R. China
  • Received:2019-08-11 Online:2020-01-15 Published:2020-01-15

Abstract: This paper discussed the application value of resting brain functional magnetic resonance imaging (rs-fMRI) in evaluating resting brain function changes in patients with post-stroke epilepsy. 125 Eighty patients with post-stroke epilepsy admitted to our hospital from May 2017 to May 2019 were selected as the observation group, and 53 healthy people in the same period were selected as the control group. Both groups completed the rs-fMRI examination, we collected relevant data, calculated and compared the amplitude of low frequency fluctuations (ALFF) values of the whole brain of the two groups. The resting state functional connectivity (rsFC) between ALFF and all voxels in cerebellum (cerebellum) was calculated and compared. Compared with the control group, the ALFF in the right anterior cuneiform lobe and left middle frontal gyrus increased significantly, while ALFF in the right hippocampus, right cerebellar foot area 2 and left cerebellum area 4/5 decreased significantly in patients with post-stroke epilepsy (P<0.05). The ALFF differentially located areas (right hippocampus, right anterior cuneiform lobe and left middle frontal gyrus) were used as seed areas, the rsFC values in left cerebellum area 8 and right cerebellum area 4/5 were significantly increased in patients with post-stroke epilepsy (P<0.05). The seed regions were ALFF differential regions (right cerebellar foot 2 and left cerebellar 4/5), the rsFC values of the left inferior frontal gyrus and the right middle temporal gyrus were significantly lower in patients with post-stroke epilepsy (P<0.05). The results show that the functional connectivity of multiple brain areas between the brain and cerebellum of patients with post-stroke epilepsy has changed. rs-fMRI can objectively evaluate the changes of resting brain function of patients, and provide imaging basis for clinical diagnosis, treatment and prognosis evaluation.

Key words: post-stroke epilepsy, resting state functional connectivity, functional magnetic resonance imaging, amplitude of low frequency fluctuations