Imaging Science and Photochemistry ›› 2020, Vol. 38 ›› Issue (3): 453-458.DOI: 10.7517/issn.1674-0475.191019

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Comparative Analysis of Brain CT and MRI in the Diagnosis of Brain Damage in Children with Hyperbilirubinemia

LI Juan, LIU Xiaoxia, WANG Dong, LI Jian, CAI Ya   

  1. Department of Radiology, The First Affiliated Hospital of Air Force Military Medical University, Xi'an 710032, Shaanxi, P. R. China
  • Received:2019-10-30 Online:2020-05-15 Published:2020-05-15

Abstract: In order to analyze the effects of cranial CT and magnetic resonance imaging (MRI) in the diagnosis of brain damage in children with hyperbilirubinemia, 50 children with hyperbilirubinemia were selected as subjects. According to the results of brainstem auditory evoked potential (BAEP), they were divided into normal group (24 cases) and abnormal group (26 cases). 25 healthy full-term neonates were chosen as the control group. Serum bilirubin (TB) levels and behavioral neurological scores (NBNA) were compared among the three groups. Head CT and MRI were performed in children with hyperbilirubinemia. BAEP was used as the gold standard to analyze the clinical effects of CT, MRI and the combination of the two in the diagnosis of brain damage in children with hyperbilirubinemia. The results showed that the TB level in the BAEP normal group and the BAEP abnormal group was significantly higher than that in the control group, and the NBNA score was significantly lower than that in the control group, and the TB level of BAEP abnormal group was significantly higher than that of the BAEP normal group, and the NBNA score was significantly lower than that of the BAEP normal group. The sensitivity and accuracy of MRI in the diagnosis of hyperbilirubinemia is higher than that of CT. The combined detection can improve the specificity and accuracy of diagnosis and reduce the rate of misdiagnosis.

Key words: hyperbilirubinemia, CT, MRI, brain injury