Application of MRI Enhanced Scan Combined with DWI Detection in Diagnosis of Breast Cancer

doi:10.7517/issn.1674-0475.191205

Abstract

Abstract: In this paper, we explored the effect of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI) combined with diffusion-weighted MRI (DWI) in the diagnosis of breast cancer. 81 cases of breast cancer confirmed by surgery and pathology in our hospital from August 2015 to August 2017 were retrospectively analyzed, DCE-MRI and DWI were detected before operation. The time-signal intensity curve (TIC) was drawn, and the diffusion coefficient (ADC) value was detected. With pathological results as the gold standard, the diagnostic accuracies of single detection and combined detection were analyzed. ROC was used to analyze the effect of ADC in the diagnosis of breast cancer. The pathology results showed that, in 81 cases, 37 cases were benign and 44 cases were malignant. The sensitivity and accuracy of joint detection of DCE-MRI and DWI were significantly higher than those of single detection (P<0.05); the distribution of TIC in benign and malignant lesions was statistically significant (P<0.05); the ADC value of malignant lesions was significantly lower than that of benign lesions (P<0.05). The best limit value of ADC for diagnosis of benign and malignant breast cancer was 1.28×10^-3 mm²/s, the sensitivity was 86.5%, and the specificity was 90.9%, respectively. Therefore, the combined detection of DCE-MRI and DWI can improve the diagnostic accuracy of benign and malignant breast cancer, and provide reliable imaging basis for clinical practice.

Key words: MRI enhanced scan, diffusion weighted imaging, breast cancer

FU Ziwen, YANG Hua. Application of MRI Enhanced Scan Combined with DWI Detection in Diagnosis of Breast Cancer[J]. Imaging Science and Photochemistry, 2020, 38(3): 540-545.

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