Imaging Science and Photochemistry ›› 2020, Vol. 38 ›› Issue (4): 748-752.DOI: 10.7517/issn.1674.0475.200325

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The Value of Fibroscan Combined with Blood NLR and PDW in Predicting the Prognosis of Liver Cirrhosis Caused by Chronic HBV Infection and Its Relationship with Liver Function

ZHAO Conglin1, LI Shuyi2, ZHANG Yanjun3   

  1. 1. Department of Infection, Tangshan Infectious Diseases Hospital, Tangshan 063000, Hebei, P. R. China;
    2. Internal Medicine Department, The Ninth Hospital of Tangshan, Tangshan 063000, Hebei, P. R. China;
    3. Department of Radiology, The Fourth Hospital of Tangshan, Tangshan 063000, Hebei, P. R. China
  • Received:2020-03-30 Online:2020-07-15 Published:2020-07-15

Abstract: In this paper, we analyzed the predictive value of FibroScan combined with blood NLR and PDW on the prognosis of liver cirrhosis caused by chronic HBV infection and its relationship with liver function. We selected 86 patients with chronic HBV infection-related cirrhosis for retrospective analysis, and they were divided into the complication group (n=48) and the non-complication group (n=38) according to the prognosis of patients with or without cirrhotic complications. The hardness values of liver and spleen, levels of blood NLR/PDW, serum liver function indexes (AST, ALT, TBIL) of FibroScan in the two groups were measured and compared. The relationship between hardness values of liver and spleen, blood NLR/PDW levels and liver function of patients were explored, and the predictive value of liver and spleen hardness values, blood NLR/PDW on prognosis were observed. The results showed that the hardness values of liver and spleen, blood NLR/PDW and serum AST, ALT, TBIL levels in the complication group were higher than those in the non-complication group (P<0.05); the hardness values of liver and spleen, blood NLR/PDW levels were positively correlated with serum AST, ALT, TBIL levels of patients (P<0.05). The efficacy of hardness values of liver and spleen in predicting the prognosis of patients with complications were higher, as well as the blood MLR/PDW. The sensitivity of joint prediction was 83.33%, and the specificity was 81.58%. It can be seen that FibroScan combined with blood NLR/PDW has a higher value in predicting the prognosis of cirrhosis associated with chronic HBV infection, and is closely related to the liver function of patients.

Key words: FibroScan, NLR, PDW, cirrhosis associated with chronic HBV infection