DEVELOPMENT OF SECOND GENERATIONAL PORPHYRIN-BASED PHOTOSENSITIZERS

doi:10.7517/j.issn.1674-0475.2002.02.131

Abstract

Abstract: The current state of seond generational prophyrin based photosensitizers used in photodynamic therapy (PDT) is reviewed,which are most chlorins in the stages of clinical and pre-clinical trials.The research on photophysical properties showed that they are powerful photodynamic drugs.Some biological molecule linked porphyrins and boronated derivatives are also presented,which may have good future used for phototherapeutic agents.

Key words: photosensitizer, porphyrin, chlorin, photodynamic therapy, photophysics

CLC Number:

O644

MA Jin-shi . DEVELOPMENT OF SECOND GENERATIONAL PORPHYRIN-BASED PHOTOSENSITIZERS[J]. Imaging Science and Photochemistry, 2002, 20(2): 131-148.

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