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Development of Photoresist Resins and Their Synthesis Methods for Extreme Ultraviolet Lithography WEN Shuai, LIU Qiang IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (4): 504-511.   DOI: 10.7517/issn.1674-0475.210122 Abstract （1016）   HTML （56）    PDF （2249KB）（622）       Knowledge map    Save Extreme ultraviolet lithography (EUVL) has become the most productive technology to achieve the manufacturing of integrated circuit at 22 nm node and beyond. In this paper, the structural characteristics of the EUV photoresist resins and their effects on photolithographic properties were introduced. Based on the structures and synthesis methods of photoresists, the polymeric synthesis methods of chemically and non-chemically amplified EUV resists were mainly reviewed. Finally, the direction of structural design for EUV photoresist in the future was forecasted. Reference | Related Articles | Metrics

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Preliminary Study of Enhanced CT Parameters in Differential Diagnosis of Benign and Malignant Renal Tumors ZHANG Qinglin, ZHUANG Meixiang, LUO Xueping IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (6): 845-848.   DOI: 10.7517/issn.1674-0475.210505 Abstract （584）   HTML （8）    PDF （487KB）（18）       Knowledge map    Save This study explored the value of enhanced CT scan parameters in differentiating benign and malignant renal tumors. 66 patients with renal tumors were selected, all patients were given enhanced CT scanning, 30 were malignant and 36 were benign. The CT value of lesions, the relative renal cortex corrected CT value and the relative renal cortex corrected CT value in the excretion phase in the malignant group were significantly lower than those in the benign group ( P<0.05), and the gray value ratio in the malignant group was significantly higher than that in the benign group ( P<0.05). The area under the ROC curve of CT value, gray value ratio, relative renal cortex corrected CT value and relative renal cortex corrected CT value in the diagnosis of renal malignant tumor were 0.732, 0.731, 0.772 and 0.843, respectively, P<0.05. Logistic regression was established for lesion CT value, grayscale value ratio, relative cortical corrected CT value in plain scan period and relative cortical corrected CT value in excretory period, the area under the ROC curve of this model for the diagnosis of renal malignant tumor was 0.940, P<0.05. The parameters of enhanced CT have a good application value in the differential diagnosis of benign and malignant renal tumors. Reference | Related Articles | Metrics

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Application of Indocyanine Green in Bioimaging and Medical Engineering ZHOU Qiaoyu, XU Jiajia, LIU Min, MA Xin, HUANG Yurou, WU Yandong, CHEN Qiong, YIN Jun IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (4): 487-491.   DOI: 10.7517/issn.1674-0475.210110 Abstract （568）   HTML （29）    PDF （1652KB）（294）       Knowledge map    Save Indocyanine green (ICG), a cationic cyanine dye, has the advantages of low toxicity, high affinity and near-infrared emission. Therefore, as a kind of near-infrared organic fluorescent dye which can be used in clinical medicine, it has been widely applied in biological imaging, disease diagnosis and other fields. In this paper, the clinical application and tumor diagnosis and treatment of indocyanine green were discussed, and the relevant information about ICG was comprehensively introduced through examples. Reference | Related Articles | Metrics

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Synthesis and Lithographic Performance of Molecular Glass Photoresists with Covalently Bonded Photo-acid Generator ZHANG Weijie, CHEN Jinping, YU Tianjun, ZENG Yi, LI Yi IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (2): 211-219.   DOI: 10.7517/issn.1674-0475.211001 Abstract （533）   HTML （33）    PDF （2705KB）（274）       Knowledge map    Save A molecular glass material HPS-MSF covalently bonded with photoacid generator (PAG) was designed and synthesized. It exhibits good thermal stability and film-forming properties. A negative-tone molecular glass photoresist based on HPS-MSF as the main material and 1,3,4,6-tetrakis(methoxymethyl)glycoluril (TMMGU) as the cross-linking agent was prepared. The formulation, post-baking and development conditions of the photoresist were initially studied by 254 nm ultraviolet exposure. The negative-tone photoresist was further evaluated using electron beam lithography. Patterns of a line width of 150 nm in period of 300 nm were obtained at exposure doses of 140 μC/cm 2 and 110 μC/cm 2 for photoresist containing 15% and 30% TMMGU, respectively. Reference | Related Articles | Metrics

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The Value of Contrast-enhanced Ultrasound and Dynamic Contrast-enhanced Magnetic Resonance Imaging in the Diagnosis of Breast Non-mass-like Enhancement Lesions LI Lihuan, WANG Fan IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (3): 381-385.   DOI: 10.7517/issn.1674-0475.201111 Abstract （493）   HTML （3）    PDF （1084KB）（65）       Knowledge map    Save The purpose of this study was to investigate the value of contrast-enhanced ultrasound (CEUS) and dynamic enhanced magnetic resonance imaging (DCE-MRI) in the diagnosis of benign and malignant breast lesions of non-mass-like enhancement (NMLE). There were 120 patients with NMLE lesions who were selected and be examined by CEUS and DCE-MRI respectively. The experimental results showed that 92 cases of malignant lesions and 28 cases of benign lesions were confirmed by pathology. In CEUS, the proportion of high enhancement, fast-forward enhancement and fast-out regression in malignant lesions were significantly higher than that in benign lesions ( P<0.05). In DCE-MRI, the proportion of malignant lesions with segmental distribution and internal enhancement in clusters were significantly higher than that of benign lesions ( P<0.05), while the apparent diffusion coefficient (ADC) was significantly lower than that of benign lesions ( P<0.05). There was no significant difference between these two methods in the diagnostic efficacy for breast NMLE lesion. This study confirmed that CEUS and DCE-MRI have good application value in the diagnosis of benign and malignant lesions of NMLE. Reference | Related Articles | Metrics

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Comparative Study of Enhanced CT and Enhanced Magnetic Resonance Imaging in the Diagnosis of Hepatocellular Carcinoma CHEN Yue, SHEN Junjie IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (6): 831-835.   DOI: 10.7517/issn.1674-0475.210403 Abstract （442）   HTML （6）    PDF （522KB）（27）       Knowledge map    Save The purpose of this study was to explore the comparative study of contrast-enhanced CT and contrast-enhanced magnetic resonance imaging (CE-MRI) in the assessment of the size and blood supply of hepatocellular carcinoma (HCC), 112 lesions of 102 patients with HCC were selected, the contrast-enhanced CT and CE-MRI images were compared, chi square test was used to test the differences in sensitivity and specificity between the groups, and Kappa was used to test the consistency of the two methods.The HCC diagnostic sensitivity, specificity and accuracy of enhanced CT and CE-MRI were 90.29% and 94.17%, 88.89% and 88.89%, 90.18% and 93.75% respectively, and the difference was not statistically significant ( P>0.05). The lesions measured by contrast-enhanced CT and CE-MRI was not statistically significant ( P>0.05). In female and male patients, there was no significant difference in the volume of lesions measured by contrast-enhanced CT and CE-MRI ( P>0.05). Among 112 lesions, 99 lesions with rich blood supply and 3 lesions with poor blood supply were determined by contrast-enhanced CT and CE-MRI. The consistency of Kappa value of blood supply was determined by contrast-enhanced CT and CE-MRI was 0.668, P< 0.05. There was no significant difference in blood supply between male and female patients by contrast-enhanced CT and CE-MRI ( P>0.05). Contrast-enhanced CT and CE-MRI showed good consistency in the size and blood supply assessment of HCC. Reference | Related Articles | Metrics

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Efficacy and Significance of Predicting Fetal Intrauterine Growth Restriction Based on Ultrasound Detection of S/D, IFI and CPR BAI Yanhong, RAO Hongjie, LI Min IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (2): 243-247.   DOI: 10.7517/issn.1674-0475.210902 Abstract （425）   HTML （4）    PDF （920KB）（40）       Knowledge map    Save In this paper, the ultrasound detection of cord blood flow during systolic maximum blood flow peak/diastolic minimum blood flow peak (S/D), fetal aortic isthmus blood flow index (IFI), brain placental rate (CPR) to predict fetal intrauterine growth restriction (IUGR) efficacy and significance were studied. A total of 498 pregnant women who underwent prenatal check-ups were selected as the research objects. According to whether IUGR occurred, they were divided into IUGR group ( n=33) and no IUGR group ( n=465). The baseline data of the two groups were compared. S/D, IFI, CPR, estimation fetal weight (EFW), and statistical analysis of the data. The results showed that the S/D (2.90±0.52) of the IUGR group was higher than that of the no IUGR group ( P<0.05), and the IFI (0.75±0.44), CPR (1.18±0.38), and EFW [(2169.33±483.05)g] were lower than those without IUGR ( P<0.05) in the IUGR group; S/D was negatively correlated with EFW, and IFI, CPR and EFW were positively correlated ( P<0.05). After the control of hypertension and EFW during pregnancy, S/D, IFI and CPR were still related to the occurrence of IUGR ( P<0.05). Therefore, the combined detection of S/D, IFI, CPR, and EFW by ultrasound can be used as an effective program to evaluate IUGR, and provide a reference for clinical diagnosis and treatment. Reference | Related Articles | Metrics

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Application of Dynamic Contrast-enhanced MRI and CT in Differential Diagnosis of Adrenal Adenoma and Metastasis YANG Guangyang, LONG Haiqing, ZHANG Ying, YANG Hailang, SU Qiang, ZHAO Weihua IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (6): 849-853.   DOI: 10.7517/issn.1674-0475.210508 Abstract （414）   HTML （7）    PDF （1058KB）（27）       Knowledge map    Save This study investigated the application of dynamic contrast-enhanced MRI and CT in the differential diagnosis of adrenal adenoma and metastasis. 73 patients with adrenal tumors were divided into adrenal adenoma group and adrenal metastasis group according to the type of adrenal tumors. All of patients underwent DCE MRI and CT. The relevant parameters were recorded to analyze the tumor clearance rates based on MRI examination with CT clearance rate at each time point. There were significant between-group differences about tumor size and morphology, T2WI signal, enhancement degree and plain scan CT value ( P<0.05). After 3 min, 5 min, 7 min and 9 min of injection, CT clearance rates between groups were significantly different ( P<0.05). After 5 min, 7 min and 9 min of injection, MRI clearance rate were positively correlated with CT clearance rate. Dynamic contrast-enhanced MRI and CT examination is important to differential diagnosis of adrenal adenoma and metastasis. Reference | Related Articles | Metrics

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Study on Off-axis Dual-wavelength Holographic Imaging GE Lei, WEN Yongfu, CHENG Haobo IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (6): 790-797.   DOI: 10.7517/issn.1674-0475.210801 Abstract （373）   HTML （166）    PDF （1625KB）（119）       Knowledge map    Save Digital holographic microscopy (DHM) is a commonly used technique to obtain quantitative information by measuring the phase shifts in light and changes in the refractive index of the sample. In view of the small measurement depth of the single-wavelength holographic microscopic imaging system and the phase ambiguity of the phase unwrapping algorithm, a reflective mode dual-wavelength digital holographic microscopy utilizing dichroic mirror for quantitative phase imaging of 3D structures with extended thickness range is presented, which is based on dual-wavelength off-axis interference technology. This is done by simultaneous acquisition of two off-axis interferograms, each at a different wavelength, and generation of a synthetic wavelength, allowing for an extension of the measurement range. This method is explored by numerical simulation, and then a dual-wavelength digital holographic experimental setup is constructed for imaging the polishing spots obtained by magnetorheological polishing technology and USAF target. In conclusion, the effectiveness and feasibility of the system are preliminarily verified. Reference | Related Articles | Metrics

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A Fluorescent Probe for Detecting the Iodide Ion in Aqueous Solution LIU Luying, FAN Yuandong, WANG Jing, WANG Jingshan, XIE Haoyuan, XIE Lijun IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (3): 354-358.   DOI: 10.7517/issn.1674-0475.201006 Abstract （368）   HTML （8）    PDF （1904KB）（95）       Knowledge map    Save In this paper, anhydrous citric acid and N-( β-aminoethyl- γ-aminopropyl) methyldimethoxysilane were used to prepare carbon quantum dots by hydrothermal method. The carbon quantum dot emits blue light, and the excitation wavelength and emission wavelength were 370 nm and 466 nm, respectively. Due to the heavy atom effect of iodine and the ability of iodine ions to easily donate electrons, fluorescence quenching occurs when carbon quantum dots encounter iodide ions in an aqueous solution. By measuring the fluorescence lifetime, it was found that there was a dynamic quenching effect between carbon quantum dots and iodide ions. Using this feature, a fluorescent probe for selective detection of iodide ions in aqueous solution was established. Optimize the influence of the dispersion solvent on the fluorescence intensity of carbon quantum dots, and the influence of response time and pH on the quenching efficiency. Under the optimal experimental conditions:the fluorescence change value ( F 0- F) with the logarithm of iodide ion concentration was linear, the linear equation was Y=427.60 X+646.88, R 2=0.9945, and the linear range was 5×10 -7-5×10 -4 mol/L, the detection limit was 3.2×10 -8 mol/L. The recovery range was 101%-105% when three concentrations spiked were used to test the water samples. Reference | Related Articles | Metrics

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Predictive Value of Tan Score for Recurrent Infarction in Elderly Patients with AIS ZHAO Hongying, ZHANG Huifang, YANG Guotao, GU Qianqian, WANG Wenhao, WANG Haibin IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (3): 631-635.   DOI: 10.7517/issn.1674-0475.211209 Abstract （347）   HTML （3）    PDF （633KB）（47）       Knowledge map    Save This paper discussed the predictive value of CT middle cerebral artery regional collateral scoring system - Tan score for recurrent infarction in elderly patients with acute ischemic stroke (AIS). 140 elderly AIS patients were selected, including 33 patients with recurrent infarction (observation group) and 107 patients without recurrent infarction (control group), the differences of clinical data, laboratory indexes and Tan score between the two groups were observed. The age of the observation group was significantly higher than that of the control group ( P<0.05). Compared with the control group, the proportion of fibrinogen (FIB) and Tan score ≤1 in the observation group were higher ( P<0.05), while the blood flow velocity of middle cerebral artery in the observation group were lower ( P<0.05). Tan score was positively correlated with middle cerebral artery blood flow velocity ( r=0.485, P<0.05). Logistic regression showed age, middle cerebral artery blood flow velocity and Tan score were the influencing factors of recurrent infarction in elderly AIS patients ( P<0.05). The area under ROC curve of recurrent infarction predicted by Tan score was 0.685, P<0.05, and the sensitivity and specificity were 76.00% and 67.50% respectively. CT middle cerebral artery regional collateral scoring system Tan score has certain application value in predicting recurrent infarction Reference | Related Articles | Metrics

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Correlation between CT Findings and Pathological Grade of Lung Adenocarcinoma WANG Rui, MA Cailing, HU Jiuli, WANG Qiongge, HU Chanchan IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (2): 306-310.   DOI: 10.7517/issn.1674-0475.210824 Abstract （345）   HTML （3）    PDF （784KB）（60）       Knowledge map    Save This article aims to explore the correlation between CT imaging findings and histopathological grading of lung adenocarcinoma.A retrospective collection of 149 patients with pathologically confirmed lung adenocarcinoma, according to the grading standard, the patients were divided into a moderately well-differentiated group (level Ⅰ and Ⅱ), a poorly differentiated group (level Ⅲ), and the relationship between CT imaging manifestations of lung adenocarcinoma and postoperative pathological grading was analyzed. Results: (1) The smallest and largest diameters of the tumors in the moderately well-differentiated group were significantly lower than those in the poorly differentiated group ( P<0.05). (2) 47.4% of the tumor marginal signs in the moderately well-differentiated group showed lobular signs, while 68.5% in the poorly differentiated group, there was a significant difference between the two group ( P<0.01). (3) 26.3% of the moderately differentiated group has ground glass shadow, and 3.7% of the poorly differentiated group, there was a significant difference between the two group ( P<0.01). In short, the CT appearance of lung adenocarcinoma is significantly correlated with its pathological grade. Reference | Related Articles | Metrics

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Study on CT Diagnosis of Renal Space-occupying Lesions and Differentiation of Lesions Nature YUAN Lei, WEI Lai IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (3): 434-437.   DOI: 10.7517/issn.1674-0475.201008 Abstract （333）   HTML （3）    PDF （421KB）（45）       Knowledge map    Save The value of CT in the diagnosis of renal space-occupying lesions was investigated. A total of 108 cases of renal space-occupying lesions were selected to analyze the value of CT in the diagnosis of benign and malignant renal tumors, as well as the CT signs and value differences of benign and malignant renal tumors. The diameter of lesions in the malignant tumor group was (6.10±1.22) cm, which was higher than that in the benign tumor group ( P<0.05).In the CT signs of malignant tumors, the proportion of non-uniform enhancement and enhancement mainly in fast-forward and fast-backward was 54.17% and 47.22%, which were significantly higher than that of benign tumors ( P<0.05).The arterial CT value of malignant tumor was (78.29±12.12) HU, which was higher than that of benign tumor ( P<0.05).The sensitivity, specificity, accuracy of CT in the diagnosis of benign and malignant tumors were 90.28%, 83.33% and 87.96%. CT has a good value in the diagnosis of renal space-occupying lesions and the differentiation of lesion properties. Reference | Related Articles | Metrics

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Diagnostic Analysis of Coronary CTA in Patients with Coronary Stenosis and Bifurcation Lesions MA Teng, HONG Fangyan, ZHAO Qiang IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (2): 434-438.   DOI: 10.7517/issn.1674-0475.210929 Abstract （320）   HTML （4）    PDF （738KB）（46）       Knowledge map    Save The study explored the diagnostic value of coronary CT angiography (CTA) in patients with coronary stenosis and bifurcation lesions. A total of 84 patients with coronary heart disease who underwent CTA examination and coronary angiography (CAG) for clinical research. The results of CTA and CAG examinations of each segment of the coronary artery and the left coronary artery were compared.Using CAG as the diagnostic gold standard.The diagnostic value of CTA for coronary artery stenosis, coronary artery disease with different degrees of stenosis, and left coronary artery bifurcation disease were calculated. The sensitivity of CTA in diagnosing coronary artery stenosis in patients with coronary heart disease is 89.61%, and the specificity is 91.73%. The consistency of the degree of coronary artery stenosis in patients with coronary heart disease diagnosed by CTA and the CAG result Kappa value was 0.761, P<0.05. The sensitivity and specificity of left coronary artery bifurcation lesions in patients with coronary heart disease diagnosed by CTA was 86.36% and 90.00%. As a non-invasive examination method, CTA has high diagnostic value for coronary artery stenosis and bifurcation lesions in patients with coronary heart disease, and has high consistency with CAG results. Reference | Related Articles | Metrics

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Effect of Large-pitch Scanning Combined with Energy Spectrum CT Double-low Subtraction in Carotid CTA and the Influence on the Dose of Radiation and Contrast Medium ZHAO Xinyun, LI Man IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (3): 375-380.   DOI: 10.7517/issn.1674-0475.201103 Abstract （313）   HTML （2）    PDF （969KB）（55）       Knowledge map    Save In this paper, the application effect of large-pitch scanning combined with energy spectrum CT double-low subtraction in the process of carotid CT angiography (CTA) were explored, as well as the influence on the radiation dose and the dose of contrast agent. We chose 86 cases of cerebral insufficiency caused by carotid artery disease, and all patients underwent carotid CTA. Among them, 43 cases underwent conventional scanning mode as the control group, and the other 43 cases underwent large-pitch scanning combined with energy spectrum CT double low subtraction method as the study group. The results showed that the CT values of each segment of the carotid artery CTA in the study group were higher than those in the control group ( P<0.05). The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the common carotid artery and internal carotid artery in the study group were higher than those in the control group ( P<0.05). The average score of image quality in the study group was higher than that of the control group ( P<0.05). The difference of suprasellar cortex in the study group was lower than that of the control group, 375 and the score of bone removal effect was higher than that of the control group ( P<0.05). The dose length product (DLP) of the study group were less than those of the control group ( P<0.05), as well as CT dose index (CTDlvol), effective dose (ED) and iodine intake. It can be seen that the application of large-pitch scanning and energy spectrum CT double-low subtraction for carotid CTA can significantly improve the inspection effect and the image quality, and reduce the radiation dose and the amount of contrast agent. Reference | Related Articles | Metrics

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Diagnosis and Analysis of Rotator Cuff Injury in Female Badminton Athletes with MRI PDW-SPAIR Sequence ZHANG Ling, AN Yifan, FAN Yong, QIU Mingqiang IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (3): 680-684.   DOI: 10.7517/issn.1674-0475.211131 Abstract （313）   HTML （5）    PDF （587KB）（53）       Knowledge map    Save This research explored the value of magnetic resonance proton density-weighted spectral attenuated inversion recovery (PDW-SPAIR) sequence in the diagnosis of rotator cuff injury in female badminton players and its comparison with arthroscopic findings. 76 female badminton players treated for shoulder disease were selected and underwent magnetic resonance PDW-SPAIR sequence and arthroscopy. Through inspection and analysis, 68.42% of them were rotator cuff injuries; the sensitivity, specificity and accuracy of magnetic resonance PDW-SPAIR sequence in diagnosing patients with rotator cuff injury were 96.15%, 91.67%, and 94.74%, respectively, and compared with arthroscopic diagnosis, there was no significant difference ( P>0.05). It was high consistency between magnetic resonance PDW-SPAIR sequence diagnosis of rotator cuff injury in patients with injury grading and arthroscopic diagnosis (Kappa value 0.981). The preoperative magnetic resonance PDW-SPAIR sequence rotator cuff fatty infiltration score of patients with rotator cuff injury confirmed by magnetic resonance PDW-SPAIR sequence examination was higher than that during surgery ( P<0.05). This shows the magnetic resonance PDW-SPAIR sequence has high diagnostic performance in the diagnosis of rotator cuff injury in female badminton players, and its diagnosis of rotator cuff injury patients has a high consistency with arthroscopic diagnosis. Reference | Related Articles | Metrics

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Comparative Analysis of Benign and Malignant Properties of Breast Molybdenum Target and Contrast-enhanced Ultrasonography in Differential Diagnosis of Breast Non-mass-like Lesions ZHAO Ting, JIANG Shiliang IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (4): 512-516.   DOI: 10.7517/issn.1674-0475.201113 Abstract （312）   HTML （2）    PDF （2844KB）（76）       Knowledge map    Save The purpose of this study was to explore the value of mammography and contrast-enhanced ultrasonography in the diagnosis of breast non-mass-like lesions (NMLE). A total of 110 cases of NMLE were selected for mammography and contrast-enhanced ultrasonography, and were compared with pathological results. The results show that 87 cases of malignant lesions and 23 cases of benign lesions were confirmed by pathology. The mammography of malignant lesions showed the proportion of calcification, asymmetry or disorder, irregular high density were significantly higher than that in benign lesions ( P<0.05). There was significant difference in the contrast-enhanced manifestations of malignant and benign lesions ( P<0.05). The sensitivity, accuracy and negative predictive value of contrast-enhanced ultrasound in the diagnosis of benign and malignant lesions were significantly higher than those of mammography ( P<0.05). The results showed that compare with mammography, contrast-enhanced ultrasonography has a higher value in differentiating benign and malignant lesions of NMLE, which is worth clinical use. Reference | Related Articles | Metrics

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Application of Low Oxygen Inhibition Thiol-acrylate System in Upconversion Particles Assisted Near-Infrared Photopolymerization PAN Yue, YANG Tianqing, HU Peng, SANG Xinxin, LIU Ren IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (2): 203-210.   DOI: 10.7517/issn.1674-0475.210901 Abstract （307）   HTML （13）    PDF （3428KB）（90）       Knowledge map    Save The presence of oxygen inhibition effect in radical photopolymerization leads to incomplete curing in the surfaces and affects the final performance of cured material. In this work, the insensitivity of thiol-acrylate system to oxygen was introduced into the upconversion particles assisted near-infrared photopolymerization (UCAP) to overcome the oxygen inhibition effect of acrylate system. The effects of the UCPs concentration, the structure and content of thiol monomers on the oxygen inhibition degree were systematically studied by combining thiols with (meth)acrylate monomers. The ATR-FTIR were used to characterize the polymerization kinetics of monocomponent (meth)acrylate and thiol-acrylate systems in UCAP. The double bond conversion at different depths of the cured material was characterized by Confocal Raman Microscopy. The results show that in the mixed system of secondary mercaptan PE-1 and acrylate monomer EM2261 with 2.0wt% UCPs and 50% -SH molarity, the maximum double bond conversion of 82% was obtained on the surface and over 90% in the deep layer, the oxygen inhibition degree of the surface layer were effectively reduced. Reference | Related Articles | Metrics

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Analysis of Correlation between SWE Imaging Technical Parameters and Peak, Tp, MTT and Combined Diagnostic Value of Thyroid Benign and Malignant Nodules ZHAO Hengda, WANG Yi IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (4): 526-532.   DOI: 10.7517/issn.1674-0475.201207 Abstract （306）   HTML （3）    PDF （1535KB）（66）       Knowledge map    Save The purpose of this study is to explore the correlation between shear wave elastography (SWE) technical parameters and contrast-enhanced ultrasound (CEUS) parameters of benign and malignant thyroid nodules, and the value of combined diagnosis of benign and malignant thyroid nodules by SWE and CEUS. Fifty-one patients with malignant thyroid nodules in our hospital were selected as the malignant group, and 63 patients with benign thyroid nodules were selected as the benign group. All of them underwent SWE and CEUS examinations. The diagnostic value was analyzed. The results of the study found that E min, E mean, E max and Peak was negatively correlated and positively correlated with Tp ( P<0.05); the AUC value of the combined diagnosis of malignant thyroid nodules by SWE and CEUS was 0.952, which was greater than any single index diagnosis ( P<0.05); E min, E mean, E max, Tp, MTT is positively correlated with clinical stage, nodule size, and calcification, and negatively correlated with the degree of differentiation. Peak is negatively correlated with clinical stage, nodule size, and calcification, and positively correlated with the degree of differentiation ( P<0.05). These results can be It is confirmed that the combination of SWE technology and CEUS in the diagnosis of thyroid benign and malignant nodules is of high value, and plays an important role in guiding clinical development of treatment plans. Reference | Related Articles | Metrics

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Study on CT Multi-sign Diagnosis and Differential Diagnosis of Fungal Infection of Rhinosinus HU Fengling, LI Yanyan, WANG Junda IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (6): 798-802.   DOI: 10.7517/issn.1674-0475.210731 Abstract （300）   HTML （12）    PDF （1946KB）（45）       Knowledge map    Save This study explored the diagnosis and differential diagnosis of rhinosinus sinuses with multiple CT signs and multiple signs combined in the diagnosis and differential diagnosis of rhinosinus fungal infections. A total of 107 patients with complete nasal sinus CT scan data and nasal endoscopic histopathological examination are selected with menstruation in the Department of Otolaryngology as the research objects. The gender, age, and CT signs are analyzed. The study showed that the CT signs of fungal infection of the nose and sinuses and other sinus diseases were statistically significant ( P<0.05); multivariate logistic regression analysis showed that the soft tissues had high density and calcification in the soft tissues, adjacent to the sinus wall bone hyper-plasia and sclerosis, the lesion is located in the maxillary sinus, which is an independent risk sign; a combined drawing model of the three signs has the highest diagnostic value. Therefore, CT scan multiple signs are of great value for the diagnosis of rhinosinus fungal infections, which can im-prove the accuracy of diagnosis. Reference | Related Articles | Metrics

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MRI Image Enhancement Method by Gradient Field Transform WU Mengfei, XUE Xucheng, LAN Taiji, XU Xinwei IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (2): 225-231.   DOI: 10.7517/issn.1674-0475.211002 Abstract （300）   HTML （6）    PDF （2967KB）（92）       Knowledge map    Save An improved gamma correction image enhancement method is proposed to solve the shortcomings of unclear outline, fuzzy details and excessive noise of some MRI. Firstly, the image is transformed into gradient domain to obtain the gradient field of the image. Then, the image is divided into two different gradient intervals according to the threshold, and the corresponding gamma transform is carried out in different gradient ranges to establish the target gradient field. Finally, the enhanced image is reconstructed according to the transformed target gradient field. In the process of image reconstruction, the enhanced image is obtained by numerically solving the Poisson equation. In order to solve the problem of large amount of computation of traditional algorithms, this paper first divides the image into blocks, and then combines and stitches it. The results show that this algorithm can greatly improve the information entropy and image average difference of the original image. Taking a 512×512 MRI selected in this paper as an example, this algorithm improves the information entropy of the original image from 5.50 to 6.94, and the image average difference from 33.70 to 67.44. Experimental results show that this method can effectively improve the detail and contour information of MRI without improving the image noise. Reference | Related Articles | Metrics

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Application of Preoperative 3D Printing Model Simulating Operation in Percutaneous Nephrolithotomy based on CT Three-dimensional Reconstruction Imaging ZHAO Shuxiao, LI Feng, QIN Zhibiao, BI Gewen, LEI Hua, LI Qiguang, ZHENG Fang, NING Xin, HUANG Juezhuo, GU Nengyu IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 17-22.   DOI: 10.7517/issn.1674-0475.221026 Abstract （299）   HTML （19）    PDF （887KB）（85）       Knowledge map    Save This study investigated the effect of preoperative 3D printing model based on CT 3D reconstruction imaging to simulate surgical operation in the treatment o f patients with complex kidney stones by percutaneous nephrolithotomy. 96 patients with complex kidney stones were selected,and they were randomly divided into a 3D group and a routine group with 48 cases in each group. The patients in 3D group were treated with preoperative 3D printed model simulates the operation of percutaneous ephrolithotomy based on CT three-dimensional reconstruction imaging, and the routine group only takes preoperative CT three-dimensional reconstruction for percutaneous nephrolithotomy under surgical positioning. The operation time, operative blood loss, success rate of single puncture, postoperative stone clearance rate, and the changes of peripheral blood white blood cells (WBC), hemoglobin (Hb), serum procalcitonin (PCT), C-reactive protein (CRP), cystatin C (CysC), blood urea nitrogen (BUN) and serum creatinine (Scr) were compared between the two groups, and the operative complications of the two groups were recorded. The operation time and operative blood loss in the 3D group were lower than those in the conventional group, and the success rate of single puncture in the 3D group was higher than that in the conventional group ( P<0.05). The level of CysC at 24 hours after operation was lower than that of the routine group ( P<0.05). The changes of peripheral blood WBC, Hb, serum PCT, and CRP of the two groups of patients were monitored before surgery, 24 hours after surgery, and 72 hours after surgery. There was no significant difference in the change trends of peripheral blood WBC, Hb, serum PCT and CRP between 3D group and routine group ( P>0.05). After surgery the complications were counted in the two groups, the complication rate of the 3D group was 4.17% which lower than that of the conventional group 16.67% ( P<0.05). The preoperative 3D printing model simulation based on CT 3D reconstruction imaging can effectively shorten the operation time, reduce the blood loss, improve the single success rate, and reduce the degree of damage to the patient's renal function. Reference | Related Articles | Metrics

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Study of CDFI Parameters and Ultrasound Scores in the Diagnosis of Intrauterine Adhesions ZENG Xiaofen, LI Na, PENG Weiling IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (2): 248-252.   DOI: 10.7517/issn.1674-0475.210903 Abstract （298）   HTML （5）    PDF （984KB）（50）       Knowledge map    Save This study explored the value of color Doppler flow imaging (CDFI) and ultrasound scoring in the diagnosis of intrauterine adhesions. A total of 120 patients with intrauterine adhesions confirmed by hysteroscopy were selected as the adhesion group, and 120 women without intrauterine adhesions were selected as the control group. Both groups received two-dimensional ultrasound and CDFI. The measured values of uterine artery pulsation index (PI), resistance index (RI), vascular index (VI), and blood flow index (FI) in the adhesion group were lower than those in the control group ( P<0.05). The ultrasound score of the adhesion group was higher than that of the control group, and the difference was significant ( P<0.05). The measured values of PI, RI, VI, and FI of the severe adhesion group were lower than those of the mild and moderate groups ( P<0.05). The ultrasound score of the severe adhesion group was higher than the mild and moderate groups ( P<0.05). The PI, VI, and FI values of the moderate adhesion group were lower than those of the mild group ( P<0.05). The ultrasound score of the moderate adhesion group was higher than that of the mild group ( P<0.05). The AUC values of PI, RI, VI, FI, and ultrasound scores for the diagnosis of intrauterine adhesions were 0.684, 0.634, 0.814, 0.671, 0.905, respectively. The AUC of the five combined diagnoses was 0.939. CDFI and ultrasound scores have the advantages of convenience and non-invasiveness in clinical diagnosis of 248 intrauterine adhesions, especially the use of ultrasound scores for diagnosis has high value. Reference | Related Articles | Metrics

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Application Value of Enhanced CT in Staging and Prognosis Evaluation of Esophageal Carcinoma CHEN Jiang, WU Tao IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (4): 606-610.   DOI: 10.7517/issn.1674-0475.201119 Abstract （296）   HTML （1）    PDF （536KB）（58）       Knowledge map    Save The purpose of this study was to investigate the application value of enhanced CT in the stage and prognosis evaluation of esophageal cancer. A total of 252 cases of esophageal cancer patients were selected for enhanced CT scan with 16-slice CT scanner. The diagnostic accuracy of enhanced CT in the T3 and T4 stages of esophageal cancer was higher than that in the T1 and T2 stages ( P<0.05). There was no significant difference in the diagnostic accuracy of N0 and N1 stage by enhanced CT in patients with esophageal cancer ( P>0.05). During the follow-up to October 2017, the short-term efficacy and 2-year local control rate of patients with homogeneous lymph node density were higher than those of patients with low-density and marginal enhanced internal necrosis; the short-term efficacy and 2-year local control rate of patients with low-density were higher than those of patients with marginal enhanced internal necrosis ( P<0.05). The short-term efficacy and 2-year local control rate of patients with regular lymph node margin were higher than those with irregular lymph node margin and obvious invasion ( P<0.05). It is suggested that enhanced CT plays an important role in the evaluation of preoperative clinical staging of esophageal cancer patients and prognosis of chemotherapy patients, and has guiding significance for the follow-up treatment of patients. Reference | Related Articles | Metrics

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The Characteristics of BND, V-BN-S Parameters in Patients with SUI after Natural Delivery Diagnosed by Transvaginal Ultrasound and the Changes before and after Rehabilitation Treatment JIANG Xiaohua, CHEN Huijuan, LU Xiaoer IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (4): 560-563.   DOI: 10.7517/issn.1674-0475.201120 Abstract （294）   HTML （4）    PDF （472KB）（34）       Knowledge map    Save The characteristics of bladder neck movement (BND), bladder neck position (V-BN-S), resting bladder neck position (R-BN-S), and urethral rotation angle (UR) in patients with stress urinary incontinence (SUI) after natural delivery and the changes before and after rehabilitation treatment were investigated. A total of 110 SUI patients after natural delivery were selected as the observation group and 100 cases without SUI after natural delivery were selected as the control group. The BND,V-BN-S,R-BN-S and UR were measured by transvaginal ultrasound. The BND and UR in the observation group were significantly higher than those in the control group, V-BN-S and R-BN-S were significantly lower than those in the control group ( P<0.05).The BND and UR of severe patients in the observation group were significantly higher than those in mild and moderate patients, V-BN-S and R-BN-S were significantly lower than those in mild and moderate patients ( P<0.05).The BND and UR of the observation group after rehabilitation treatment were significantly lower than those before treatment, while V-BN-S and R-BN-S were significantly higher than before treatment ( P<0.05). The condition of SUI patients in the observation group was significantly improved after rehabilitation treatment. Reference | Related Articles | Metrics

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The Clinical Significance of TIBI Classification and TCD Blood Flow Reversal before and after Thrombolysis in MCA Occlusion Patients CHEN Shangchao, HU Mingyan IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (3): 459-463.   DOI: 10.7517/issn.1674-0475.211116 Abstract （293）   HTML （6）    PDF （688KB）（53）       Knowledge map    Save This study explored the relationship between the transcranial Doppler (TCD) assessment of cerebral ischemia thrombolytic classification (TIBI), TCD blood flow reversal and the prognosis of patients with acute middle cerebral artery (MCA) occlusive stroke. Chosen 144 MCA occlusive stroke patients as the research objects, all patients were treated with intravenous alteplase thrombolysis. According to the prognosis of patients within 90 days of onset, they were divided into a good prognosis group with 98 cases and a poor prognosis group with 46 cases, and compared the cerebral ischemia thrombolysis classification (TIBI) and TCD blood flow reversal before and after thrombolysis between the two groups. Re-examined 24 hours after the operation, the TIBI blood flow classification distribution of the good prognosis group was better than that of the poor prognosis group ( P<0.05). The AUC values of TIBI blood flow improvement and TCD blood flow reversal rate predicted the prognosis of patients with MCA occlusive stroke after thrombolytic therapy were 0.757 and 0.578, respectively. The higher NIHSS scores, diabetes, coronary heart disease, and atrial fibrillation at admission would significantly increase the risk of poor prognosis on admission ( P<0.05). After thrombolysis, TIBI blood flow was improved and TCD blood flow was improved and reversal reduced the risk of poor prognosis in patients ( P<0.05). Through early observation of TIBI blood flow improvement after thrombolytic therapy and TCD blood flow reversal could have a certain clinical value for evaluating the prognosis of patients, and the two can effectively complement each other. Reference | Related Articles | Metrics

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Diagnostic Value of CT Myocardial Perfusion Imaging and ECV in OMI and Their Relationship with Myocardial Injury LIU Shuo, ZHOU Hao, ZHANG Mengqi, Palidan Nyaz IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (6): 911-915.   DOI: 10.7517/issn.1674-0475.210511 Abstract （292）   HTML （4）    PDF （576KB）（21）       Knowledge map    Save This study explored the value of CT myocardial perfusion imaging (CT-MPI) and extracellular volume (ECV) in the diagnosis of old myocardial infarction (OMI) and their correlation with myocardial injury. A total of 82 patients with OMI were selected as the observation group and 30 healthy subjects in the same period were selected as the control group. The CT-MPI parameters and ECV of the two groups were compared, the influencing factors of OMI and the relationship between CT-MPI parameters, ECV and myocardial injury indexes were analyzed, and the diagnostic value of CT-MPI parameters and ECV for OMI was evaluated. The levels of cTnI, cTnT and ECV in the observation group were higher than those in the control group, MBF and MBV were lower than those in the control group, and all indexes were the influencing factors of OMI ( P<0.05); MBF and MBV were negatively correlated with cTnI and cTnT levels, while ECV was positively correlated with cTnI and cTnT levels ( P<0.05). The maximum AUC of OMI diagnosed by MBF, MBV and ECV was 0.950. CT-MPI parameters MBF, MBV and ECV are related to myocardial injury in patients with OMI. The detection of CT-MPI parameters and ECV can effectively diagnose OMI and facilitate clinical diagnosis and treatment. Reference | Related Articles | Metrics

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MSCT Findings and Clinical Significance of Spinal Tuberculosis Patients with Incomplete Paralysis ZHANG Yali, LUO Xiaobo, ZHAO Qian IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (4): 564-568.   DOI: 10.7517/issn.1674-0475.201209 Abstract （285）   HTML （0）    PDF （535KB）（32）       Knowledge map    Save The purpose of this study was to investigate the multi-slice spiral CT (MSCT) imaging manifestations and clinical significance of spinal tuberculosis patients with incomplete paralysis before operation. 72 patients (observation group) with incomplete paralysis before spinal tuberculosis surgery in our hospital were selected, including Frankel spinal cord injury classification: 24 cases of grade B, 27 cases of grade C, and 21 cases of grade D, and 90 cases of spinal tuberculosis patients with normal muscle strength were selected as the control group, and the differences of MSCT imaging features between the two groups were analyzed and compared. In the observation group, the proportion of three or more vertebral injuries and the distribution proportion of the diseased vertebral chest segment and above were significantly higher than those in the control group ( P<0.05). In the observation group, the ratio of osseous spinal canal incomplete, total vertebral height loss ≥1 vertebral body, paravertebral abscess and compression object compression vertebral canal, compression foramina ratio and kyphosis Cobb Angle were significantly564 higher than those in the control group ( P<0.05). In the observation group, the proportion of osseous spinal incomplete in Frankel grade B patients were higher than that in Grade C and D patients ( P<0.05). In the observation group, the ratio of paravertreal abscess and compression material to compress vertebral canal, the ratio of compression foramina and kyphosis Cobb Angle in Frankel grade B patients were higher than those in Grade D patients ( P<0.05). Compared with spinal tuberculosis with normal muscle strength, MSCT images of spinal tuberculosis patients with preoperative paraplegia are different, and there are also certain differences among different Frankel grades. Reference | Related Articles | Metrics

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The Diagnostic Efficiency of IVIM-DWI in Benign and Malignant Ovarian Tumors and the Correlation with Tumor Markers and Clinicopathological Factors LIN Dong, HUANG Jiajie, WU Shangwen, QIN Ni, XU Huali IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (3): 407-411.   DOI: 10.7517/issn.1674-0475.201015 Abstract （280）   HTML （5）    PDF （896KB）（67）       Knowledge map    Save The aim of this study was to investigate the value of introvoxel incoherent motion diffusion-weighted magnetic resonance imaging (IVIM-DWI) in the diagnosis of benign and malignant ovarian tumor. There were 108 patients with ovarian tumors who were selected to compare the differences of IVMI-DWI parameters between benign and malignant tumors. The results showed that the IVIM-DWI parameters including apparent diffusion coefficient (ADC), slow diffusion coefficient (D slow) and fast diffusion coefficient score ( f value) of malignant tumor were lower than that of benign tumor ( P<0.05). The area under ROC curve of ADC, Dslow and f value in the diagnosis of malignant ovarian tumor were 0.816, 0.915 and 0.852, respectively ( P<0.05). ADC and D slow were negatively correlated with carbohydrate antigen 125(CA125) ( r=-0.457 and -0.553, P<0.05). The ADC in patients with clinical stage Ⅲ-Ⅳ was significantly lower than that of patients Ⅰ-Ⅱ ( P<0.05). In a word, IVIM-DWI parameters have a certain application value in the diagnosis of benign and malignant ovarian tumors, and the ADC, D slow levels are correlated with CA125 and clinical stage of patients with malignant tumors.407 Reference | Related Articles | Metrics

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Recent Progress of Biological Imaging Based on Monochiral Semiconducting Single-walled Carbon Nanotubes XU Wenjing, HOU Juncai, ZHAO Jianwen IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (3): 348-353.   DOI: 10.7517/issn.1674-0475.210402 Abstract （279）   HTML （8）    PDF （2238KB）（113）       Knowledge map    Save Semiconducting single-walled carbon nanotubes (sc-SWCNTs) have shown obvious advantages in biomedical applications such as biological imaging, photothermal therapy and drug delivery. In particular, they exhibit excellent properties for biological imaging due to their inherent fluorescence and strong optical absorption in the near infrared biological window (0.7-1.4 μm). Sc-SWCNT can be used in not only fluorescently labeling cells in deep imaging in vivo, but also tracking and treating tumor cells, which have attracted widespread attention. The electronic band structure and photoelectric properties of sc-SWCNTs depend on their chirality. The advantages of sc-SWCNTs themselves can be maximized only when using monochiral sc-SWCNTs for biomedical applications. The separation of monochiral sc-SWCNTs and their applications in new optoelectronic devices and bioluminescence imaging have become research hotspots at the forefront of science and technology. In this paper, we will introduce the separation technology of sc-SWCNTs and the research progress of monochiral sc-SWCNTs in the field of biological imaging. Reference | Related Articles | Metrics

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The Changes of Pelvic Floor Ultrasound Parameters and Urodynamic Indexes after Hysterectomy and the Effect of Rehabilitation Treatment ZHOU Qin, LI Qi, ZHANG Yuanyuan IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (3): 596-600.   DOI: 10.7517/issn.1674-0475.211124 Abstract （279）   HTML （3）    PDF （531KB）（37）       Knowledge map    Save This study explored the changes of pelvic floor ultrasound parameters and urodynamic parameters before and after total hysterectomy in patients with cervical cancer and the effect of pelvic floor rehabilitation. 137 cases of cervical cancer patients undergoing total hysterectomy were selected for clinical research. All patients were tested for pelvic floor ultrasound parameters and urodynamic parameters before and 3 months after surgery, among them, 120 patients received pelvic floor rehabilitation after surgery. The results showed: the measured value of the bladder neck reduction, the urethral rotation angle, the posterior angle of the bladder neck in the resting state, the posterior angle of the bladder and the urethra in the maximum Valsalva state, and the vertical distance between the bladder neck and the underside of the pubic symphysis (BSD) all increased to a certain extent compared with those before the operation ( P<0.05). After the operation, the patient’s bladder compliance, maximum urine flow rate, and maximum detrusor pressure were significantly lower than those before the operation ( P<0.05), and the maximum bladder volume was significantly increased ( P<0.05). Total hysterectomy will have obvious adverse effects on the pelvic floor function and bladder voiding function for patients with cervical cancer. This part of patients should be given appropriate rehabilitation after the operation to promote the recovery of function and improve the quality of life. Reference | Related Articles | Metrics

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Diagnostic Value of CT Combined with High Resolution Pelvic MRI in Colorectal Cancer ZOU Huayu, ZHOU Yinpin IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (3): 479-482.   DOI: 10.7517/issn.1674-0475.201114 Abstract （277）   HTML （4）    PDF （728KB）（163）       Knowledge map    Save In order to investigate the diagnostic value of CT combined with high-resolution pelvic MRI in colorectal cancer,179 suspected patients with colorectal cancer were selected in this study. All subjects were examined by CT and pelvic MRI. T stage, negative predictive value, positive predictive value and diagnostic efficacy were compared and observed. The results showed that the accuracy of CT in T staging was 92.11%,and the accuracy of T staging was 98.68% with CT+ high-resolution pelvic MRI. Compared with CT detection, CT+ high-resolution pelvic MRI detection showed low positive predictive value, low specificity and high accuracy, but there was no statistical significance between the two ( P>0.05). Compared with CT detection, CT+ high-resolution pelvic MRI detection had higher negative predictive value and sensitivity, and the difference was statistically significant ( P<0.05). CT combined with high-resolution pelvic MRI scan for the detection of colorectal cancer patients can improve the detection rate of the disease and improve the accuracy. Reference | Related Articles | Metrics

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The Value of SWE Parameter Elastic Modulus in the Diagnosis of Axillary Lymph Node Metastasis in Breast Cancer CHEN Jia, LI Ling IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (4): 533-537.   DOI: 10.7517/issn.1674-0475.201208 Abstract （273）   HTML （1）    PDF （561KB）（42）       Knowledge map    Save The purpose of this study was to explore the value of real-time shear wave elastography (SWE) parameter modulus of elasticity in the diagnosis of axillary lymph node metastasis of breast cancer. A total of 240 breast cancer patients were selected for SWE examination, all patients underwent surgical resection and axillary lymph node (ALN) resection. The SWE images of the ALN positive group showed sclerosing sign, black hole sign, uneven distribution of the lesion elasticity, non-uniform abnormal color inside the lesion, and red of color hardness spectrum were significantly higher than those of the ALN negative group ( P<0.05). The maximum value of elastic modulus ( E max), mean value of elastic modulus ( E mean), standard deviation (SD) and ratio of the average elastic modulus ( E ratio) in the ALN positive group were significantly higher than those in the ALN negative group ( P<0.05). The results of Logistic regression analysis showed that non-uniform abnormal color inside the lesion, E max, E mean and E ratio were the influencing factors for ALN metastasis in breast cancer patients ( P<0.05). The value of the elastic modulus of SWE parameter has a certain diagnostic value in ALN metastasis of breast cancer, which is worth clinical use. Reference | Related Articles | Metrics

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Magnetic Resonance Imaging Study of Brain Function and Structure Changes in Patients with Post-herpetic Neuralgia BAI Lala, YANG Wei, ZHOU Miao, HUANG Guobiao IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (2): 286-290.   DOI: 10.7517/issn.1674-0475.211101 Abstract （273）   HTML （3）    PDF （832KB）（43）       Knowledge map    Save This study explored the clinical value of magnetic resonance imaging (MRI) in patients with post-herpetic neuralgia (PHN) in assessing brain functional divisions and gray matter volume changes. Thirty-four patients with PHN (PHN group) and 40 healthy volunteers (control group) were selected as the research subjects. They received resting state functional magnetic resonance imaging (rs-FMRI), and the differences in low-frequency amplitude values between the PHN group and the control group were compared. The results showed that the low-frequency amplitude values of the PHN group in the brain stem, left and right temporal lobes, left and right frontal lobes, right anterior cingulate gyrus, and right parietal lobe were higher than those in the control group ( P<0.05). The low-frequency amplitude values of PHN group had left and right insula, middle frontal gyrus, left and right central anterior gyrus, right hippocampus, and right fusiform gyrus were significantly lower than those of the control group ( P<0.05). The amplitude increases of low-frequency in brain stem, left and right temporal lobes, left and right frontal lobes, and right cingulate gyrus and left parietal lobe of PHN patients were positively correlated with the VAS score. Low-frequency amplitude reduction values of left and right insula, middle frontal gyrus, left and right central anterior gyrus, right para 286 hippocampal gyrus, and right fusiform gyrus were negatively correlated with the VAS score. In the resting state, the brain functional areas of PHN patients changed compared with the normal population, which may be related to the increased pain perception level of the patients. Reference | Related Articles | Metrics

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Evaluation of 3.0T MRI on the Degree of Injury and Therapeutic Effect of Patients with Lateral Ankle Ligament Injury LIU Junli, BAO Pengcheng IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (6): 865-870.   DOI: 10.7517/issn.1674-0475.210407 Abstract （272）   HTML （5）    PDF （1100KB）（16）       Knowledge map    Save A total of 80 patients with lateral ligament injury of ankle joint were selected as the research object to explore the significance of 3.0T magnetic resonance imaging (MRI) in the evaluation of injury degree and treatment effect. The thickness of the anterior talofibular ligament in the affected side was higher than that in the healthy side ( P<0.05). The thickness of the anterior talofibular ligament in the affected side was positively correlated with the degree of injury ( P<0.05). The degree of injury, course of disease, previous ankle injury, and the thickness of the anterior talofibular ligament at 4, 8 and 12 weeks after treatment were all the influencing factors for the poor curative effect of patients with lateral ankle ligament injury ( P<0.05). The AUC values of talofibular anterior ligament thickness were 0.760, 0.823 and 0.869 at 4, 8 and 12 weeks after treatment, respectively. The AUC value was the highest at 12 weeks after treatment. Therefore, 3.0T MRI can clearly show the pathological changes after lateral ankle ligament injury, accurately evaluate the location and degree of injury, which is conducive to clinical efficacy evaluation, and provide accurate imaging basis for the selection of the best treatment method. Reference | Related Articles | Metrics

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Recent Progress in Bio-responsive Gadolinium-based MRI Contrast Agent LIU Yanyue, WU Yongjie, SUN Kang, TAO Ke IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (6): 781-789.   DOI: 10.7517/issn.1674-0475.210409 Abstract （272）   HTML （173）    PDF （2729KB）（92）       Knowledge map    Save The gadolinium-based contrast agent (GBCA), the most common contrast agent in clinical magnetic resonance (MR) imaging, lacks specificity when detecting diseases and thus makes it difficult to distinguish lesions. Many recent researches have focused on the development of bio-responsive contrast agents which can vary the intensity of MR signals with changes in physiological or pathological environment. This article reviews three current design concepts of bio-responsive GBCAs, expounds the specific methods of promoting relaxation rate and its application in imaging diagnosis, makes a prospect for the development of bio-responsive GBCA, and points out the problems to be solved in the conversion process for clinical application. Reference | Related Articles | Metrics

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Application of Transvaginal Ultrasound Combined with Transabdominal Ultrasound in the Diagnosis of Ectopic Pregnancy LIU Jufang, ZHU Silai, XU Dan IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (3): 483-485.   DOI: 10.7517/issn.1674-0475.201016 Abstract （272）   HTML （7）    PDF （428KB）（85）       Knowledge map    Save The purpose of this study was to explore the value of transvaginal ultrasound combined with transabdominal ultrasound in the diagnosis of ectopic pregnancy. A total of 130 patients with suspected ectopic pregnancy were selected as the research subjects, the transvaginal ultrasound and transabdominal ultrasound were performed. Among the 130 suspected ectopic pregnancy patients, 103 cases were diagnosed as ectopic pregnancy, 27 cases were non ectopic pregnancy. The detection rates of pelvic effusion, cardiovascular pulsation and adnexal mass in transvaginal ultrasound were higher than those of transabdominal ultrasound ( P<0.05).The sensitivity, accuracy and negative predictive value of transvaginal ultrasound combined with transabdominal ultrasound in the diagnosis of ectopic pregnancy were all higher than that of transvaginal ultrasound and transabdominal ultrasound ( P<0.05).Therefore, transvaginal ultrasound combined with transabdominal ultrasound has good diagnostic value. Reference | Related Articles | Metrics

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Comparative Analysis of Contrast-enhanced Ultrasound Combined with BI-RADS Grading and Pathological Examination of Breast Cancer ZOU Fang, WANG Shuang IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (4): 620-623.   DOI: 10.7517/issn.1674-0475.201107 Abstract （270）   HTML （2）    PDF （471KB）（49）       Knowledge map    Save The purpose of this study was to investigate the diagnostic value of contrast-enhanced ultrasound combined with BI-RADS grading in breast cancer. 130 cases of suspected breast cancer patients were selected, the routine ultrasound and contrast-enhanced ultrasound were given to analyze the value of contrast-enhanced ultrasound combined with conventional BI-RADS grading in the diagnosis of breast cancer. Among 130 suspected patients, 47 cases were benign, 83 cases of malignant patients; the experimental results showed that: In the ultrasonic imaging features of malignant lesions, the proportion of centripetal enhancement and enhanced lesions enlargement were significantly higher than those of benign lesions ( P<0.05). The enhancement start time, time to peak and peak intensity of malignant lesions were significantly lower than those of benign lesions ( P<0.05). Compared contrast-enhanced ultrasound and BI-RADS, the sensitivity and negative predictive value and accuracy of combined examination in the diagnosis of breast cancer were higher ( P<0.05). This study confirmed that: Contrast-enhanced ultrasound combined with BI-RADS has good clinical value in diagnosing breast cancer, which is worthy of clinical use. Reference | Related Articles | Metrics

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The Value of WBS Combined with SPECT/CT Tomographic Fusion in the Diagnosis of Solitary Bone Metastases in Extremities of Lung Cancer WU Fengping, WU Jing IMAGING SCIENCE AND PHOTOCHEMISTRY    2021, 39 (6): 808-812.   DOI: 10.7517/issn.1674-0475.210520 Abstract （270）   HTML （8）    PDF （586KB）（38）       Knowledge map    Save The purpose of this study was to investigate the value of whole body bone scan (WBS) combined with single photon emission computed tomography (SPECT)/CT fusion in the diagnosis of single bone metastasis in lung cancer limbs. A retrospective study was conducted, 140 cases of lung cancer patients were selected and given WBS, SPECT/CT tomographic fusion examination. The proportion of adenocarcinoma in the bone metastasis group was significantly higher than that in benign bone lesions ( P<0.05). The proportion of bone destruction, density change of bone marrow cavity and bone cortical defect in the bone metastasis group were significantly higher than that in benign bone lesions ( P<0.05). The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of WBS combined with SPECT/CT in diagnosis of bone metastasis were significantly higher than those of WBS ( P<0.05). WBS combined with SPECT/CT fusion has a good value in the diagnosis of single bone metastasis in extremities of lung cance. Reference | Related Articles | Metrics

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Evaluation of DCE-MRI Parameters for Postoperative Femoral Head Necrosis in Patients with Femoral Neck Fractures YANG Junzhong, HU Hao, LI Jiabin, LI Liang, HUANG Pan IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (5): 1143-1147.   DOI: 10.7517/issn.1674-0475.220326 Abstract （269）   HTML （2）    PDF （638KB）（36）       Knowledge map    Save This study investigated the value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in evaluating the blood supply of the femoral head in patients with femoral neck fracture and its relationship with postoperative complications of femoral head necrosis. A retrospective study of 52 patients with femoral neck fractures was selected, and the patients were grouped according to whether they had femoral head necrosis within 12 months after surgery. Among them, 130 cases without femoral head necrosis were classified as non-necrosis group, and 22 cases with femoral head necrosis were classified as necrosis group. All patients underwent DCE-MRI before surgery, 5 days after surgery, and 3 months after surgery. The peak time of the same region of interest (ROI) in the upper outer and inner upper quadrant of the affected side in the necrosis group was higher than that in the non-necrosis group at 5 days and 3 months after operation ( P<0.05). Increased age, preoperative traction, Garden classification type IV, and prolonged peak time of upper outer quadrant or upper inner quadrant 5 days after operation were independent risk factors for postoperative femoral head necrosis in patients with femoral neck fracture ( P<0.05). Postoperative professional rehabilitation was a protective factor for patients with femoral head necrosis ( P<0.05). DCE-MRI has a certain value in evaluating the occurrence of femoral head necrosis after surgery, and it has a guiding significance for early clinical diagnosis and timely intervention measures. Reference | Related Articles | Metrics