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The Role of Contrast-enhanced Ultrasound in the Detection of Carotid Intraplaque Neovascularization in Coronary Heart Disease and Its Relationship with the Expression of Serum Hcy SUN Xiang, TAN Jie IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (6): 1402-1406.   DOI: 10.7517/issn.1674-0475.220725 Abstract （145）   HTML （3）    PDF （817KB）（713）       Knowledge map    Save This study investigated the role of contrast-enhanced ultrasonography (CEUS) in the detection of carotid plaque neovascularization (IPN) in coronary artery disease and its relationship with the expression of serum homocysteine (Hcy) and blood lipids. A total of 167 patients with stable coronary heart disease (CAD) and carotid plaque (thickness ≥1.5 mm) were selected as the research subjects. IPN was examined by CEUS, and the patients were divided into IPN group ( n=82) and non-IPN group ( n=85). The baseline data, carotid ultrasound characteristics, blood lipid metabolism indexes, serum Hcy levels, and the incidence and occurrence time of major adverse cardiovascular events (MACE) were compared between the two groups. The results showed that the maximum plaque thickness in the IPN group was higher than that in the non-IPN group [(3.23±1.07) mm vs (2.85±0.87) mm, P＜0.05]. There was no significant difference in TC, TG, HDL-C and LDL-C between the two groups ( P>0.05). The serum Hcy level in the IPN group was higher than that in the non-IPN group ( P＜0.05). The overall incidence of MACE was 7.19% (12/167). The Kaplan-Meier survival curve of patients’ MACE showed that the occurrence time of MACE in patients with IPN was earlier than in non-IPN group at follow-up ( P＜0.05). This study suggests that IPN, maximum plaque thickness and serum Hcy levels may be predictors of adverse cardiovascular events in patients with coronary heart disease. Reference | Related Articles | Metrics

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The Effect of Preoperative Tranexamic Acid on Blood Coagulation Function and Blood Flow Parameters of Lower Limbs in KOA Patients YUN Tianbin, DING Jie IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (3): 550-554.   DOI: 10.7517/issn.1674-0475.211119 Abstract （205）   HTML （1）    PDF （623KB）（155）       Knowledge map    Save This study explored the effects of preoperative administration of tranexamic acid on surgical blood loss, blood coagulation status, and lower limb ultrasound blood flow parameters in KOA patients undergoing medial open wedge-shaped high tibial osteotomy. Ninety-four patients who intend to undergo medial open wedge tibial high osteotomy were selected for related research. Using the random number table generated by statistical software, the patients were divided into the test group and the control group with 47 cases in each. The patients in the test group were given preoperatively for tranexamic acid, while only given the same amount of normal saline in the control group instead, and the rest of the treatment measures remained the same. Compared the operation time, apparent blood loss, hidden blood loss, total blood loss and the length of hospital stay between the two groups, and the hemoglobin (Hb), hematocrit, D-dimer, thromboelastogram (TEG) parameters and the average blood flow velocity of the lower limb veins before and after the operation. The apparent blood loss, hidden blood loss, and total blood loss of the test groups were lower than in the control group ( P<0.05). Seventy-two hours after the operation, the Hb value of the test group was higher than that in the control group ( P<0.05). The incidence of deep vein thrombosis (DVT) in the test group was 4.26% compared 550with 2.13% in the control group, and the difference was not statistically significant ( P>0.05). Preoperative intravenous infusion of tranexamic acid is beneficial to reduce surgical blood loss and postoperative hidden blood loss, but it could not significantly affect the patient’s TEG parameters and lower limb blood flow velocity, and could not significantly increase the incidence of DVT. Reference | Related Articles | Metrics

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Research Progress of Ultrasound in Classification, Diagnosis and Treatment of Cesarean Scar Pregnancy LIU Yingying, ZHANG Jieying, WAN Hui, DU Jianwen IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 1-5.   DOI: 10.7517/issn.1674-0475.221036 Abstract （251）   HTML （29）    PDF （755KB）（122）       Knowledge map    Save With an increased cesarean delivery rate and the advent of the "one couple two children" policy, the increase in the number of women who choose to become pregnant again despite having a previous cesarean section, and the incidence of abnormal placentation is steadily rising. Cesarean scar pregnancy is a special pregnancy in which the placenta position is abnormal and reaches the incision of the lower segment of uterus and invades the muscular layer. Because of the nonspecific clinical features, once CSP patients fail to receive reasonable diagnosis and treatment in the first trimester of pregnancy, serious obstetric complications may occur with the progress of gestational weeks, such as uterine rupture, severe hemorrhage, shock and so on, which pose a serious threat to the life and health of pregnant women. Therefore, pregnant women with a history of cesarean section need to use some auxiliary examinations in time to avoid risks as much as possible. Ultrasonography, as a common examination method in gynecology, shows great application potential in the diagnosis and treatment of CSP. This article reviews the progress of ultrasound in the diagnosis of scar pregnancy. Reference | Related Articles | Metrics

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Application of MRI Combined with Transrectal Ultrasound Targeted Puncture in the Diagnosis of Prostate Cancer NIU Ben, CAO Hui IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 6-10.   DOI: 10.7517/issn.1674-0475.221024 Abstract （261）   HTML （25）    PDF （693KB）（115）       Knowledge map    Save This study explored the application of MRI combined with transrectal ultrasound (TRUS) targeted puncture in the diagnosis of prostate cancer (PCA). 234 patients with prostate disease diagnosed by MRI combined with transrectal ultrasound targeted puncture were selected as the targeted group, including 114 patients with PCA (PCA group) and 120 patients with benign prostatic hyperplasia (benign group), and then the imaging features of the two groups were compared. In addition, 106 patients in the same period with prostate disease who received traditional 12-needle transrectal ultrasound puncture were selected as the control group. Compared the number of puncture needles and the length of cancer tissue obtained by the two puncture methods. The results showed that in MRI features, the proportion of patients with low T2WI signal, irregular lesion morphology, blurred lesion boundary and diffusion-weighted imaging with high signal in PCA group was significantly higher than that in benign group ( P<0.05). Comparison of ultrasound imaging features, the proportion of patients with hypoecho, irregular shape of lesions, microcalcified lesions, posterior echo attenuation, and blood flow grade (2-3) in PCA group was significantly higher than that in benign group ( P<0.05). The average number of puncture needles in the targeted group was significantly lower than that in the control group ( P<0.05). The length of cancer tissue obtained by puncture in the targeted group was longer than that in the control group ( P<0.05). MRI combined with transrectal ultrasound targeted puncture has higher clinical value in the diagnosis of prostate cancer. Reference | Related Articles | Metrics

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MRI Diagnosis of Sports Meniscus Injury and Evaluation of Postoperative Rehabilitation Effect LI Yan, ZHAO Hailing, LI Wei, ZHAO Dan IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (3): 675-679.   DOI: 10.7517/issn.1674-0475.211206 Abstract （225）   HTML （7）    PDF （901KB）（111）       Knowledge map    Save This article investigated the value of magnetic resonance imaging (MRI) in diagnosing the degree of sports-induced meniscus injury in young and middle-aged patients and the postoperative rehabilitation effect of patients. A retrospective study was performed on 98 patients with sports-induced meniscus injury treated. All patients received high-frequency ultrasound and MRI examinations before surgery, and all patients received arthroscopic surgical repair. The results showed that the sensitivity and specificity of MRI in diagnosing knee meniscus injury by preoperative MRI were 90.00% and 88.16%, the sensitivity and specificity of knee ligament injury by MRI were 76.79% and 97.02% respectively. The MRI damage grade of knee meniscus at 3 months and 6 months after operation was significantly lower than that before operation, and the difference was statistically significant ( P<0.05). 6 months after the operation, the knee joint function grade was positively correlated with MRI meniscus recovery grade ( r=0.850, P<0.001). MRI has high diagnostic value in the diagnosis of young and middle-aged sports meniscus injury, and could also evaluate the postoperative rehabilitation effect of patients. Reference | Related Articles | Metrics

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Application of Preoperative 3D Printing Model Simulating Operation in Percutaneous Nephrolithotomy based on CT Three-dimensional Reconstruction Imaging ZHAO Shuxiao, LI Feng, QIN Zhibiao, BI Gewen, LEI Hua, LI Qiguang, ZHENG Fang, NING Xin, HUANG Juezhuo, GU Nengyu IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 17-22.   DOI: 10.7517/issn.1674-0475.221026 Abstract （300）   HTML （19）    PDF （887KB）（86）       Knowledge map    Save This study investigated the effect of preoperative 3D printing model based on CT 3D reconstruction imaging to simulate surgical operation in the treatment o f patients with complex kidney stones by percutaneous nephrolithotomy. 96 patients with complex kidney stones were selected,and they were randomly divided into a 3D group and a routine group with 48 cases in each group. The patients in 3D group were treated with preoperative 3D printed model simulates the operation of percutaneous ephrolithotomy based on CT three-dimensional reconstruction imaging, and the routine group only takes preoperative CT three-dimensional reconstruction for percutaneous nephrolithotomy under surgical positioning. The operation time, operative blood loss, success rate of single puncture, postoperative stone clearance rate, and the changes of peripheral blood white blood cells (WBC), hemoglobin (Hb), serum procalcitonin (PCT), C-reactive protein (CRP), cystatin C (CysC), blood urea nitrogen (BUN) and serum creatinine (Scr) were compared between the two groups, and the operative complications of the two groups were recorded. The operation time and operative blood loss in the 3D group were lower than those in the conventional group, and the success rate of single puncture in the 3D group was higher than that in the conventional group ( P<0.05). The level of CysC at 24 hours after operation was lower than that of the routine group ( P<0.05). The changes of peripheral blood WBC, Hb, serum PCT, and CRP of the two groups of patients were monitored before surgery, 24 hours after surgery, and 72 hours after surgery. There was no significant difference in the change trends of peripheral blood WBC, Hb, serum PCT and CRP between 3D group and routine group ( P>0.05). After surgery the complications were counted in the two groups, the complication rate of the 3D group was 4.17% which lower than that of the conventional group 16.67% ( P<0.05). The preoperative 3D printing model simulation based on CT 3D reconstruction imaging can effectively shorten the operation time, reduce the blood loss, improve the single success rate, and reduce the degree of damage to the patient's renal function. Reference | Related Articles | Metrics

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Application of Contrast-enhanced Ultrasound in the Diagnosis of Crohn's Disease YE Xiaoli, PENG Yongji, ZHU Jiacheng IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 28-32.   DOI: 10.7517/issn.1674-0475.221018 Abstract （227）   HTML （9）    PDF （863KB）（85）       Knowledge map    Save This study investigated the clinical value of contrast-enhanced ultrasound (CEUS) in the diagnosis of Crohn's disease (CD). 123 patients with Crohn's disease diagnosed by colonoscopy were selected as the research objects, including 89 patients in active stage and 34 patients in remission stage. All patients underwent ultrasound and CEUS examination. The intestinal wall thickness, Limberg classification of intestinal wall blood flow and CEUS quantitative analysis parameters[rise time (RT), peak intensity (PI), time to peak (TTP)] were compared between the two groups. The intestinal wall thickness of 89 patients in active stage was significantly higher than that of patients in remission stage ( P<0.05). The Limberg grade distribution of intestinal wall blood flow in active patients was higher than that in remission patients ( P<0.05). The PI value of active stage patients was significantly higher than that of remission stage patients ( P<0.05), and RT value and TTP value were significantly lower than those of remission stage patients ( P<0.05). There was no significant difference in intestinal wall thickness between patients with severe, moderate and mild activity ( P>0.05). The Limberg grade distribution of intestinal wall blood flow in patients with severe activity was higher than that in patients with mild and moderate activity ( P<0.05). The PI value of patients with severe activity was significantly higher than that of patients with mild and moderate activity ( P<0.05), and the RT and TTP value were significantly lower than those of patients with mild and moderate activity ( P<0.05). The AUC values of PI, RT and TTP in the diagnosis of Crohn's disease in remission and active phase were 0.852, 0.711 and 0.746, respectively. CEUS examination has high clinical application value in the judgment of disease condition and disease activity degree of Crohn's disease patients. Reference | Related Articles | Metrics

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Application of MR Routine and 3D-T1-VIBE Sequence Scanning in the Diagnosis of Knee Cartilage Motor Injury GAO Haoran, YANG Lianjun, ZHANG Li, CHEN Jialin, WANG Feng IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 33-37.   DOI: 10.7517/issn.1674-0475.221010 Abstract （174）   HTML （9）    PDF （851KB）（85）       Knowledge map    Save This paper explored the application value of magnetic resonance (MR) routine and 3D volume-insert air-holding examination (3D-T1-VIBE) sequence scanning in the diagnosis of patients with unilateral knee cartilage motor injury. 198 patients with suspected knee cartilage motor injury were selected as the study subjects. According knee arthroscopic diagnosis as the gold standard, 170 patients were diagnosed with knee cartilage motor injury and 28 patients with non-knee cartilage motor injury. All patients underwent routine MR, 3D-T1-VIBE sequence scanning. Compared with the MR routine and 3D-T1-VIBE sequence scanning single-item diagnosis, the combined test has a higher diagnostic accuracy for the knee joint cartilage motor injury and injury grade ( P>0.05). Compared with routine MR and 3D-T1-VIBE sequence scanning single-item diagnosis, the sensitivity (98.82%), specificity (89.28%) and accuracy (97.47%) with combined diagnoses were all higher ( P<0.05) of knee cartilage injury. MR routine combined with 3D-T1-VIBE sequence scanning is beneficial to improve the diagnostic accuracy of knee cartilage motor injury. Reference | Related Articles | Metrics

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Application of Musculoskeletal Ultrasound, SMI Combined with SWE in the Observation of the Changes of Relevant Muscle Characteristics in Patients with NLBP HAO Zhenmin, GUO Zhenning, DENG Yuguang, WU Dongqian, ZHANG Shengnan IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 79-83.   DOI: 10.7517/issn.1674-0475.221007 Abstract （195）   HTML （5）    PDF （560KB）（82）       Knowledge map    Save This paper investigated the changes of related muscle characteristics and their clinical significance in patients with non-specific low back pain (NLBP) by musculoskeletal ultrasound, superb microvascular imaging (SMI) and real-time shear wave elastography (SWE). 200 patients with NLBP were selected as the NLBP group, and 100 healthy volunteers (without signs and manifestations of lumbar pain) were selected as the control group. SMI, SWE technology and musculoskeletal ultrasound were used to determine the injury, elastic modulus and thickness of external oblique muscle, transverse abdominis muscle, iliopsoas muscle, erector spinae muscle and multifidus muscle of the two groups. All NLBP patients received rehabilitation treatment, and the changes of elastic modulus and thickness of muscle groups were observed before and after rehabilitation treatment. The thickness measurement and elastic modulus of external oblique muscle, transverse abdominis muscle, iliopsoas muscle, erector spinae muscle and multifidus muscle in NLBP group were lower than those in control group ( P<0.05). After SMI examination, the positive rate of external oblique muscle, erector spinae muscle and multifidus muscle injury in NLBP group were all higher than those in control group ( P<0.05). The thickness measurement, thickness and elastic modulus of external oblique muscle, transverse abdominis muscle, iliopsoas muscle, erector spinae muscle and multifidus muscle in NLBP group after treatment were significantly higher than those before rehabilitation treatment ( P<0.05). NLBP patients have muscle atrophy and poor muscle elastic strength, musculoskeletal ultrasound, SMI and SWE can effectively observe the changes of muscle injury, atrophy and elastic strength in patients, and quantify the rehabilitation situation. Reference | Related Articles | Metrics

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Application of SMART 3D-SMI in the Differential Diagnosis of Benign and Malignant in TI-RADS 4 Thyroid Nodules LI Chaoxi, WEN Dehui, LIU Weiliang, LU Haiyong IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (3): 510-514.   DOI: 10.7517/issn.1674-0475.211204 Abstract （260）   HTML （4）    PDF （756KB）（79）       Knowledge map    Save This study investigated the application value of 3-dimensional ultrasound imaging (smart 3D-SMI) in the differential diagnosis of benign and malignant in TI-RADS 4 thyroid nodules. 120 cases of patients (128 nodules) with TI-RADS type 4 nodules were selected and analyzed the diagnostic efficacy of CDFI, 2D-SMI and 3D-SMI for benign and malignant of TI-RADS type 4 nodules. Pathologically confirmed 84 cases benign and 44 cases malignant. TI-RADS had 87 grades 4a, 30 grades 4b and 11 grades 4c, with an accuracy rate of 67.97%. Compared with CDFI, 2D-SMI and 3D-SMI had higher blood flow grades, and detected more grade 3 blood flow. There was no statistically significant difference between 2D-SMI and 3D-SMI grades ( P＞0.05). There was no significant difference in the blood flow distribution pattern of benign nodules in CDFI, 2D-SMI and 3D-SMI ( P＞0.05). Compared with CDFI, malignant nodules showed more type Ⅲ in 2D-SMI and 3D-SMI modes ( P＜0.05). TI-RADS combined with CDFI, 2D-SMI and 3D-SMI respectively in the differential diagnosis of benign and malignant thyroid nodules, compared of the three methods, TI-RADS +3D-SMI had higher sensitivity, accuracy and negative predictive value ( P<0.05), and had no significant difference in diagnostic specificity and positive predictive value ( P＜0.05). SMART 3D-SMI can accurately assess the microvascular spatial distribution and pattern of thyroid TI-RADS 4 nodules. Reference | Related Articles | Metrics

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The Predictive Value of Clinical and Ultrasound Indicators for Intraoperative Bleeding Volume in Cesarean Scar Pregnancy ZHANG Jieying, WAN Hui, LIU Yingying, LU Yue, DU Jianwen IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (6): 358-363.   DOI: 10.7517/issn.1674-0475.230926 Abstract （63）   HTML （7）    PDF （1039KB）（78）       Knowledge map    Save To explore the risk factors affecting intraoperative bleeding volume in cesarean scar pregnancy (CSP) after cesarean section, and to search for clinical and ultrasound indicators that can predict intraoperative bleeding volume in CSP. A retrospective study was conducted to analyze the clinical and ultrasound data of 133 patients with CSP, and the patients were divided into group A (bleeding volume<100 mL) and group B (bleeding volume ≥ 100 mL) based on whether the intraoperative bleeding volume was more than 100 mL. Logistic regression model was used to analyze the risk factors related to intraoperative bleeding volume in patients. Logistic regression model screened the maximum diameter of gestational sac and the residual myometrial thickness as independent risk factors for predicting intraoperative bleeding volume, with cutoff values of 32.5 mm and 2.45 mm, respectively. In this study, we concluded that residual myometrial thickness and the maximum diameter of gestational sac are independent risk factors for predicting intraoperative bleeding volume during CSP. Reference | Related Articles | Metrics

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The Role of DCE-MRI in the Evaluation of Blood-brain-barrier Alteration after Balanced Acupuncture in Migraine without Aura and Its Relationship with Analgesic Effect ZHANG Qianqian, LI Yan, REN Hong, XIAO Aiwei, LIU Shanshan, YU Guiyong IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 11-16.   DOI: 10.7517/issn.1674-0475.221012 Abstract （220）   HTML （15）    PDF （758KB）（77）       Knowledge map    Save This paper investigated the role of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in the assessment of blood-brain-barrier alterations after balanced acupuncture in migraine without aura and its relationship with analgesic effect. 157 patients with migraine without aura were divided into a total effective group ( n=115) and ineffective group ( n=42) according to the effect of balance acupuncture. Compared the DCE-MRI blood-brain barrier parameters[bilateral thalamus, basal ganglia, amygdala, white matter blood-brain barrier penetration (Ktrans), plasma fraction (Vp)] before and after 4 weeks of treatment between the two groups. The results showed that the headache degree score was lower in the total effective group than in the ineffective group, and the amygdala Vp was higher in the pre-treatment and after 4 weeks of treatment than in the ineffective group ( P<0.05). The amygdala Vp was positively correlated with the treatment efficacy ( P<0.001). The headache degree score and pre-treatment amygdala Vp were both independent factors influencing the analgesic effect ( P<0.05), and the two combined prediction of analgesia ineffectiveness had the largest AUC. Thus Vp values of DCE-MRI can be used to reflect the efficacy of balanced acupuncture in migraine without aura, and also can be used to assess blood-brain barrier alterations, and has high diagnostic efficacy for analgesic effects. Reference | Related Articles | Metrics

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IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 0-0.   Abstract （83）   HTML （21）    PDF （404KB）（75）       Knowledge map    Save Related Articles | Metrics

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The Study of MRI and TEG Parameters in the Diagnosis of Hemorrhagic Transformation after Thrombolysis in ACI ZOU Liwen, WANG Yue, PAN Yuling, ZENG Hongjun IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 23-27.   DOI: 10.7517/issn.1674-0475.221016 Abstract （203）   HTML （8）    PDF （686KB）（68）       Knowledge map    Save This study investigated the value of magnetic resonance imaging (MRI) and thrombela-stogram (TEG) parameters in the diagnosis of hemorrhagic transformation (HT) after thrombolysis in acute cerebral infarction (ACI). 62 ACI patients with HT who received thrombolytic therapy were selected as HT group, and 80 ACI patients without HT transformation who received thrombolytic therapy at the same time were selected as control group. The MRI parameters and TEG parameters of the two groups were compared, and the final clinical diagnosis results were used as the judgment basis to calculate the value of MRI parameters and TEG in diagnosing HT in ACI patients after thrombolysis. The results showed that the phase signal characteristics of susceptibility weighted imaging (SWI) in HT group were mainly characterized by high signal, the proportion of patients with high signal in HT group was significantly higher than that in control group ( P<0.05), and the proportion of patients with low signal and mixed signal in HT group was lower than that in control group ( P<0.05). The sensitivity of SWI, diffusion weighted imaging (DWI) and T1-weighted imaging (T1WI) in the diagnosis of HT were 88.71%, 62.90% and 69.35%, respectively, and the specificity were 86.25%, 80.00% and 82.50%, respectively. The coagulation composite index (CI) value of HT group was significantly lower than that of control group ( P<0.05). The AUC values of SWI, DWI and T1WI in diagnosing HT in patients with ACI thrombolysis were 0.875, 0.715 and 0.759, respectively. The AUC value of CI value in TEG parameters for diagnosing HT in patients with ACI thrombolysis was 0.720. MRI and TEG parameters have high value in the diagnosis of HT in patients with ACI thrombolysis. Reference | Related Articles | Metrics

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Application of MRI in Preoperative Examination and Postoperative Management of Sports-induced Ankle Fractures ZHU Chao, MA Yiming IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (3): 690-695.   DOI: 10.7517/issn.1674-0475.211219 Abstract （181）   HTML （6）    PDF （596KB）（68）       Knowledge map    Save This article explored the application of MRI in the preoperative examination and postoperative management of sports-induced ankle fractures. 98 patients with ankle fractures caused by sports were selected as research objects, and used MRI to scan the ankle joints in different body positions, and then scored the ankle function according to the AOFAS scoring system. The results showed that MRI multi-planar, multi-sequence scan can clearly show the anatomical structure around the ankle ligament, significantly improve the accuracy of clinical diagnosis. The single factors related to ankle fractures include: diabetes, smoking, trauma, violence, whether the syndesmosis of the tibia and fibula was fixed during the operation, fracture reduction, fracture classification. Multi-factor analysis of ankle fracture functional recovery was related to fracture reduction and fracture classification. In short, MRI could significantly improve the accuracy of preoperative examination of sports-induced ankle fractures, and in postoperative management, the classification of ankle fractures and the reduction of fractures need to be fully evaluated. Reference | Related Articles | Metrics

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Study of Three-dimensional Speckle Tracking Imaging and DDIAS in the Diagnosis of Moderate and Severe Coronary Artery Stenosis LING Jingxia, WANG Lei, DU Xin IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 102-108.   DOI: 10.7517/issn.1674-0475.221017 Abstract （164）   HTML （5）    PDF （851KB）（67）       Knowledge map    Save This study investigated the value of three-dimensional speckle tracking imaging (3D-STI) and DNA damage-induced apoptosis suppressor (DDIAS) in the diagnosis of moderate and severe coronary artery stenosis. 112 patients with suspected coronary heart disease were examined by 3D-STI, and coronary artery stenosis was confirmed by coronary angiography (CAG) within 24 hours. Based on CAG results, the patients were divided into slight, mild, moderate, and severe groups by percentage of stenosis. At the same time, 30 healthy subjects were selected as the control group. Serum DDIAS in patients with coronary heart disease and healthy subjects were detected by enzyme-linked immunosorbent assay (ELISA). The results showed that with the increase of stenosis degree, 3D-GAS, 3D-GLS, 3D-GCS and 3D-GRS all increased gradually ( P<0.05). The level of serum DDIAS in patients with coronary heart disease was higher than that in healthy subjects, and the level of serum DDIAS gradually increased with the increase of stenosis degree ( P<0.05). The area under the ROC curve (AUC) (0.846) and sensitivity (98.28%) of 3D-GAS for diagnosing moderate and severe coronary artery stenosis were higher, but the specificity was lower (57.41%). The AUC, sensitivity and specificity of serum DDIAS in the diagnosis of moderate and severe coronary artery stenosis were 0.910, 84.48% and 90.74%, respectively. The AUC, sensitivity and specificity of 3D-STI parameters combined with serum DDIAS in the diagnosis of moderate and severe coronary artery stenosis were 0.979, 96.55% and 96.30%, respectively. The AUC and specificity of 3D-STI parameters combined with serum DDIAS in the diagnosis of moderate and severe coronary artery stenosis were higher than those of single diagnosis, and the sensitivity was second only to that of 3D-GAS alone. It is helpful for the accurate diagnosis of coronary artery stenosis. Reference | Related Articles | Metrics

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Application of 3D-MSCT in Laparoscopic Radical Resection of Right Colon Cancer ZHANG Weixing, LI Gu'nan, XIAO Tiechen IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 59-63.   DOI: 10.7517/issn.1674-0475.221001 Abstract （194）   HTML （3）    PDF （545KB）（66）       Knowledge map    Save This study explored the application value of multi-slice spiral CT three-dimensional reconstruction (3D-MSCT) in laparoscopic radical resection of right colon cancer. Collected 100 patients with right colon cancer, among them there were 61 patients with 3D-MSCT before operation (the observation group) and 39 patients (control group) underwent routine CT examination. The preoperative T stage and N stage of the two groups were analyzed. The Kappa values of preoperative T stage and pathological stage in observation group and control group were 0.821 and 0.758, respectively ( P<0.05), and the Kappa values of preoperative N stage and pathological stage were 0.825 and 0.813, respectively, P<0.05. The accuracy of preoperative T stage in observation group and control group were 88.52% and 84.62%, and the accuracy of preoperative N stage was 90.16% and 89.74%, respectively, and there was no significant difference ( P>0.05). The operation time of the observation group was significantly shorter than that of the control group, and the intra-operative blood loss and the proportion of vascular injury were significantly lower than those of the control group ( P<0.05). The levels of serum gastrin (GAS) and motilin (MTL) in the observation group were significantly higher than those in the control group ( P<0.05), while the levels of cortisol (Cor) and adrenal corticotropin (ACTH) were significantly lower than those in the control group ( P<0.05). In laparoscopic radical resection of right colon cancer, multi-slice spiral CT three-dimensional reconstruction is helpful in providing comprehensive information for the operation, avoid accidental vascular injury, and have little impact on patients' body stress and gastrointestinal function. Reference | Related Articles | Metrics

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The Value of Preoperative CT Perfusion Imaging in Predicting the Early Response of Hepatocellular Carcinoma after TACE: A Meta Analysis BI Xiaoyang, QIU Ruizhen, YANG Fujun, FAN Xiaoyan, SHUAI Shi, TANG Yanlong IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (5): 260-269.   DOI: 10.7517/issn.1674-0475.230608 Abstract （67）   HTML （7）    PDF （3875KB）（66）       Knowledge map    Save To systematically evaluate the predictive value of preoperative computed tomography perfusion imaging (CTPI) parameters in early response to transcatheter arterial chemoembolization (TACE) of hepatocellular carcinoma (HCC). The relationship between CT perfusion imaging and TACE prognosis was searched in China knowledge Network, Wanfang, VIP, PubMed, Medline, Web of Science and Embase databases by computer. Meta analysis was carried out by using RevMan 5.4 software. The mean difference (MD) was used, and each effect was expressed by 95% confidence interval (CI). A total of 7 articles were included, including 433 patients with a total of 475 tumor lesions. Meta analysis showed that there was significant difference in arterial liver perfusion (ALP) between the reactive group and the non-responsive group after TACE (MD=16.84,95%CI 2.06~31.62, P<0.05). The ALP of reactive group was significantly higher than that of non-responsive group, and the 260best cut-off value range was 9.885~22.175 mL/ (100 mL ·min). There was no significant difference in portal venous liver perfusion (PVP), hepatic perfusion index (HPI), blood flow (BF), blood volume (BV), mean transit time (MTT) and time to peak (TTP) between the reactive group and the non-responsive group after TACE. High preoperative ALP can predict the early effectiveness of liver cancer after TACE, but the more exact cut-off value of ALP needs further study. Reference | Related Articles | Metrics

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Correlation of Ultrasonic Parameters with TLR4, KL-6 and Its Significance in the Diagnosis of Pneumonia ZHANG Yinghua, YANG Ling IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 74-78.   DOI: 10.7517/issn.1674-0475.221006 Abstract （177）   HTML （5）    PDF （583KB）（65）       Knowledge map    Save This paper analyzed the correlation of ultrasound parameters with Toll-like receptor 4 (TLR4), Kerbs von den lungen-6 (KL-6) and their diagnostic value in pneumonia. 105 patients with suspected pneumonia were selected as the research subjects. Bacterial culture was used as the gold standard for the diagnosis of pneumonia, and 53 patients with pneumonia were finally diagnosed as the research group and the remaining 52 cases were the control group. All patients underwent color Doppler ultrasound detection, and detected the serum TLR4 and KL-6 levels by enzyme-linked immunosorbent assay (ELISA). The quantitative ultrasound parameters of the two groups were compared. The correlation between lung ultrasound parameters and TLR4, KL-6 levels and the severity of the disease in patients with pneumonia were analyzed, and the diagnostic value of ultrasound parameters, TLR4, KL-6 levels for pneumonia was analyzed. Compared with the control group, the parameter levels of rise time (RT) and peak intensity (PI) in the research group increased, and the time to peak (TTP) level decreased ( P<0.05). Compared with patients with mild and moderate pneumonia, the levels of RT and PI parameters, as well as the levels of TLR4 and KL-6 in patients with severe pneumonia were increased, while the levels of TTP parameters were decreased ( P<0.05). RT and PI parameters were positively correlated with TLR4 and KL-6 levels ( P<0.05), and TTP parameters were negatively correlated with TLR4 and KL-6 levels ( P<0.05). Compared with lung ultrasound parameters, TLR4 and KL-6 levels, combined diagnosis had the highest diagnostic performance for pneumonia ( P<0.05). Ultrasound parameters were correlated with TLR4, KL-6 levels and the severity of pneumonia, and the combined diagnosis of the above indicators has high diagnostic value for pneumonia. Reference | Related Articles | Metrics

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The Study of Quantitative Parameters of Carotid Ultrasound Combined with miR-128-3p in the Diagnosis of Acute Cerebral Infarction WANG Ning, PENG Zhaokuai IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 109-113.   DOI: 10.7517/issn.1674-0475.221019 Abstract （141）   HTML （2）    PDF （605KB）（64）       Knowledge map    Save This study investigated the application value of quantitative parameters of carotid ultrasound combined with microRNA 128-3p (miR-128-3p) in the diagnosis and prognosis prediction of acute cerebral infarction(ACI). 120 patients with ACI were selected as the observation group, and 100 healthy volunteers matched for age and gender were selected as the control group. The levels of miR-128-3p in peripheral blood of the two groups were detected by RT-qPCR, and carotid ultrasound examination was performed in the observation group. At the same time, the quantitative parameters of carotid ultrasound and the level of miR-128-3p difference were compared between patients with different neurological impairment and patients with different prognosis in the observation group. The relative expression of miR-128-3p in peripheral blood of the observation group was higher than that of the control group ( P<0.05). The peak systolic velocity (PSV) of patients with severe impairment was significantly lower than that of patients with mild and moderate impairment ( P<0.05), while the relative expression levels of end diastolic blood flow velocity (EDV), carotid intima-media thickness (IMT) and miR-128-3p were significantly higher than those of patients with mild and moderate impairment ( P<0.05). The PSV of patients with poor prognosis was lower than that of patients with good prognosis ( P<0.05), while the relative expression levels of EDV, IMT and miR-128-3p were higher than those of patients with good prognosis ( P<0.05). The area under the ROC curve of carotid ultrasound quantitative parameters combined with miR-128-3p for predicting poor prognosis of acute cerebral infarction was 0.986, which was higher than that predicted by each index alone ( P<0.05). PSV, EDV, IMT and the relative expression of miR-128-3p were related to the degree of neurological impairment and prognosis of patients. Quantitative parameters of carotid ultrasound combined with miR-128-3p have a certain application value in predicting the prognosis of patients. Reference | Related Articles | Metrics

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Effect Observation of Ultrasound-guided Nerve Block on Treating Herpes Zoster Neuralgia LIU Chuang, WU Yong, DING Mengyao IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 64-68.   DOI: 10.7517/issn.1674-0475.221104 Abstract （155）   HTML （7）    PDF （724KB）（64）       Knowledge map    Save This study investigated the effect of ultrasound-guided nerve block in the treatment of acute herpes zoster herpetic neuralgia and its effect on serum immune response molecules. 80 patients with acute herpetic neuralgia were selected and randomly divided into observation group and control group, 40 cases in each group. The observation group was treated with ultrasound-guided intercostal nerve block plus oral analgesic drugs and antiviral drugs, while the control group was treated with oral analgesic drugs and antiviral drugs. The operation time and block onset time of the observation group were lower than those of the control group, and the first puncture success rate of the observation group was higher than that of the control group ( P<0.05). The VAS scores of the observation group and the control group were decreased with the treatment time, and the VAS scores of the observation group were lower than those of the control group at the corresponding time points from the 1st week to the 4th week after treatment ( P<0.05). After 4 weeks of treatment, the serum immunoglobulin G (IgG) of the observation group was higher than that of the control group ( P<0.05). The levels of interleukin (IL) -10, IL-26, high mobility group protein 1 (HMGB1) and CXC chemokine ligand 10 (CXCL-10) in the observation group were lower than those in the control group ( P<0.05). Ultrasound-guided intercostal nerve block can reduce the operation time, improve the success rate of the first puncture, more effectively relieve the patient's pain, improve the patient's immune function, and regulate the level of related cytokines. Reference | Related Articles | Metrics

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The Value of the DKI Model in Magnetic Resonance Imaging for the Diagnosis of Soft Tissue Sarcoma and Its Guidance for Surgical Treatment ZHOU Yue, QI Enlin, LIU Shurong, JIANG Lijie IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 43-47.   DOI: 10.7517/issn.1674-0475.221037 Abstract （204）   HTML （9）    PDF （710KB）（63）       Knowledge map    Save This paper investigated the value of diffusion kurtosis imaging (DKI) model in magnetic resonance imaging (MRI) for the diagnosis of soft tissue sarcoma and its significance in guiding surgical treatment. 108 eight patients with soft tissue tumors were selected and divided into benign group (45 cases) and malignant group (63 cases) according to the results of surgical pathological examination. All patients underwent MRI examination assisted by DKI model. The results showed that the mean diffusion kurtosis (MK) of tumour tissue in both groups was higher than that of normal muscle tissue at the same level of the tumour, and the mean apparent diffusion coefficient (MD) was lower than that of normal muscle tissue at the same level of the tumour, with the MK in the malignant group being higher than that in the benign group and the MD lower than that in the benign group ( P<0.05). The AUC of MK and MD combined diagnosis of soft tissue sarcoma was 0.935, which was greater than that of diagnosis alone. MK was positively correlated with tumour diameter, pathological grade and invasion of blood vessels/nerves/bone in soft tissue sarcoma and MD was negatively correlated with tumour diameter, pathological grade and invasion of blood vessels/nerves/bone ( P<0.05). The relative risk of 1-year recurrence or metastasis in soft tissue sarcoma patients with high levels of MK was 6.024 times that of patients with low levels, and the relative risk of 1-year recurrence or metastasis in patients with soft tissue sarcoma with low MD level was 4.825 times that of patients with high level. It indicated that the DKI model assisted MRI in diagnosing soft tissue sarcoma was reliable, and was significantly correlated with the pathological characteristics of soft tissue sarcoma, which had a good guiding significance for surgical treatment. Reference | Related Articles | Metrics

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Application and Analysis of DCE-MRI Combined with Ultrasound in the Clinical Diagnosis of Breast Cancer CHEN Yuna, WU Yunhu, ZHOU Meijuan, DONG Jiandang IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (6): 1417-1422.   DOI: 10.7517/issn.1674-0475.220602 Abstract （143）   HTML （3）    PDF （1203KB）（63）       Knowledge map    Save This study investigated the application value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) combined with ultrasound in clinical diagnosis of breast cancer. The relevant data of 100 patients with breast tumors were retrospectively analyzed. All of the patients completed ultrasound and DCE-MRI examinations. The DCE-MRI characteristics of benign and malignant tumors were comparatively analyzed. The value of the Breast Imaging Reporting and Data System (BI-RADS) in evaluating benign and malignant breast tumors under the two examination methods was analyzed. The diagnostic value of the combination of the two was analyzed. DCE-MRI showed that the shapes, edges, internal enhancement features, and TIC curves of benign and malignant tumors were significantly different. The volume transfer constant (Ktrans) and rate constant (Kep) of malignant tumors were higher than those of benign tumors, and extracellular space volume percentage (Ve) was lower than that of benign tumors. The sensitivity, specificity and accuracy of ultrasound to diagnose benign and malignant breast tumors were 94.12%, 83.67% and 89.00%. The sensitivity, specificity and accuracy of DCE-MRI were 98.04%, 89.79% and 94.00%. The sensitivity, specificity and accuracy of combined diagnosis with the two were 100.00%, 97.95% and 99.00%. The accuracy of combined diagnosis was higher than that of ultrasonic diagnosis ( P＜0.05). The above results indicate that both DCE-MRI and breast ultrasound are helpful in nature diagnosis of breast lesions, and combined use of the two can provide more reference for the diagnosis. Reference | Related Articles | Metrics

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Influencing Factors of the Success Rate of Cecal Intubation in MSCT Virtual Colonoscopy SUN Yifei, WANG Qing, HAN Ruina, QIU Shuang IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 48-52.   DOI: 10.7517/issn.1674-0475.221105 Abstract （195）   HTML （3）    PDF （693KB）（62）       Knowledge map    Save This study mainly analyzed the factors affecting the success rate of cecal intubation during multi-slice spiral CT(MSCT) virtual colonoscopy. 95 patients undergoing MSCT virtual colonoscopy were selected as the study subjects, and 95 patients were surveyed using self-made questionnaires, and 95 questionnaires were issued and 88 were recovered. The success rate of cecal intubation in MSCT virtual colonoscopy was counted, and the failure of blind intubation were included in the control group (14 cases), the successful blind intubation were included in the study group (74 cases). Comparing the anxiety self-rating scale score (SAS) and visual simulation score (VAS) between the two groups. With the dependent variable affecting cecal intubation rate in MSCT virtual colonoscopy, the variables with P<0.05 in univariate analysis was selected for multivariate Logistic regression analysis. The results showed that the SAS score and VAS score of the study group were lower than those of the control group ( P<0.05). The success rate of cecal intubation during colonoscopy was related with age, BMI, quality of bowel preparation, bowel habits. Those who with advanced age, constipation, poor bowel preparation quality, and low cecal intubation during low BMI colonoscopy the rate of cecal intubation during colonoscopy was lower ( P<0.05). The advanced age, constipation, poor bowel preparation quality, high SAS score, low BMI, and high VAS score are the risk factors affecting the success rate of cecal intubation in multilayer spiral CT simulation colonoscopy. Reference | Related Articles | Metrics

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Application of Coronary Z-value Combined with Kobayashi Risk Score System in the Diagnosis of Coronary Artery Damage in Kawasaki Disease HUANG Baoying, JIANG Suhua, PENG Weibin, JIANG Wei IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 38-42.   DOI: 10.7517/issn.1674-0475.221029 Abstract （173）   HTML （10）    PDF （720KB）（62）       Knowledge map    Save This paper investigated the value of coronary Z-value combined with Kobayashi risk score system in evaluating coronary artery damage in Kawasaki disease(KD). 108 children with KD were selected as the research objects, and 68 children without coronary artery dilatation were finally diagnosed and included in the non-damage group. There were 40 patients in the damaged group, including 10 children with only coronary artery dilatation, 11 children with small coronary artery aneurysm, 9 children with medium coronary artery aneurysm, and 10 children with large coronary artery aneurysm. The proportion of clinical data, coronary Z-value and Kobayashi score were compared between the two groups. The proportions of age ≤ 1 year, fever duration ≥ 10 days, incomplete KD, delayed diagnosis and treatment, and Kobayashi score > 3 in the damage group were higher than those in the non-damage group ( P<0.05). Logistic regression analysis showed that age, fever duration, diagnosis and treatment time and Kobayashi score were the influencing factors of coronary artery damage in children with KD ( P<0.05). The Z-value of the left main coronary artery diameter, the Z-value of the left anterior descending coronary artery diameter, and the Z-value of the right proximal coronary artery diameter in children with medium/large coronary artery aneurysm were higher than those in children with no dilatation and only coronary artery dilatation/small coronary artery aneurysm ( P<0.05). The proportion of Kobayashi score > 3 in children with medium/large coronary aneurysms was higher than that in children without dilatation ( P<0.05). The area under the ROC curve of coronary Z-value combined with Kobayashi score in the diagnosis of medium coronary aneurysms/large coronary aneurysms was high. The incidence of coronary artery damage in Kawasaki disease is affected by age, fever duration, diagnosis and treatment time, Kobayashi score and other factors. Coronary Z-value combined with Kobayashi score has certain application value in diagnosing the severity of coronary artery damage. Reference | Related Articles | Metrics

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Evaluation of the Severity of Coronary Atherosclerotic Lesions by Integrated Cervical Cerebral Ultrasound Combined with Hcy and hs-CRP SHEN Jian, ZHANG Haoran, WANG Feng, LIU Yanwei, LI Sha, YANG Shaoshi IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 96-101.   DOI: 10.7517/issn.1674-0475.221020 Abstract （191）   HTML （5）    PDF （783KB）（61）       Knowledge map    Save This study investigated the value of intracranial and extracranial integrated cervical cerebral ultrasound features combined with homocysteine (Hcy) and high-sensitivity C-reactive protein (hs-CRP) in evaluating the degree of coronary atherosclerosis. 120 patients with suspected coronary heart disease were selected, and 82 patients were diagnosed with coronary heart disease by coronary angiography (CAG), including 45 patients with mild coronary artery stenosis and 37 patients with moderate to severe coronary artery stenosis. All patients underwent transcranial Doppler ultrasound and carotid artery ultrasound examination, compared the differences in clinical data and ultrasound parameters between patients with coronary heart disease and without coronary heart disease, patients with different degrees of coronary artery disease, and analyzed the influencing factors of moderate to severe coronary artery stenosis. The results showed that the levels of Hcy and hs-CRP in CHD patients were higher than those in non-CHD patients ( P<0.05). The age, total cholesterol (TC), triglyceride (TG), Hcy, hs-CRP, carotid Crouse plaque score and intima-media thickness (IMT) of patients with moderate to severe stenosis were higher than those of patients with mild stenosis ( P<0.05), while the mean intracranial artery velocity, end-systolic velocity (PSV) and end-diastolic velocity (EDV) were lower than those of patients with mild stenosis ( P<0.05). Carotid crouse plaque score, carotid IMT, Hcy and hs-CRP were positively correlated with Gensini score ( P<0.05). The Logistic regression equation showed that Hcy, hs-CRP, carotid Crouse plaque score and carotid IMT were the influencing factors of moderate to severe coronary artery stenosis in patients with coronary heart disease ( P<0.05). The area under the ROC curve of Logistic regression equation for predicting moderate to severe stenosis was 0.962 ( P<0.05). The intracranial and extracranial integrated cervical cerebral ultrasound features combined with Hcy and hs-CRP have a good effect on evaluating and predicting the degree of coronary atherosclerosis. Reference | Related Articles | Metrics

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Imaging Analysis of Wrist Sprain in Adults with MSCT and MRI ZHANG Hongguang, QIN Xupei, WANG Kangni IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (6): 1323-1327.   DOI: 10.7517/issn.1674-0475.220902 Abstract （200）   HTML （25）    PDF （937KB）（61）       Knowledge map    Save The wrist sprain is mostly caused by external violence. Generally, imaging examination is performed only after the sprain occurs in patients. However, due to the complex structure of wrist joint, it is still impossible to completely and accurately judge the sprain in clinical practice, and its diagnostic criteria also have some limitations, which makes it difficult to analyze the condition of wrist sprain. Due to the existence of bone overlap, X-ray is not effective in the diagnosis of wrist sprain, which is prone to image distortion, misdiagnosis and missed diagnosis. Multi slice spiral CT (MSCT) and magnetic resonance imaging (MRI) have powerful post-processing functions, which can provide accurate, intuitive and comprehensive imaging information for wrist sprain. However, there are some limitations in using the two methods alone, and joint detection can significantly reduce the occurrence of misdiagnosis and missed diagnosis. This article reviews the application of MRI combined with MSCT in wrist sprain examination, and analyzes the application value of the combined detection method to provide a basis for clinical practice. Reference | Related Articles | Metrics

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Study of Low Dose and Low Concentration Contrast Agent in 320-row Coronary Computer Tomography Angiography BAO Zhaodi, MA Zhuangfei, SONG Dandan, WANG Chao, QI Xingliang IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (6): 283-289.   DOI: 10.7517/issn.1674-0475.230925 Abstract （110）   HTML （14）    PDF （1437KB）（61）       Knowledge map    Save To explore the feasibility of low dose combined with low concentration contrast agent in 320-row coronary computer tomography (CT) angiography. 153 patients who underwent coronary computer tomography angiography were prospectively collected. 49 patients were included in group A, 52 patients were included in group B, and 52 patients were included in group C. The tube voltage of three groups were 80 kV, 100 kV and 100 kV, respectively. The concentration of contrast agent of three groups were 300 mgI/mL, 300 mgI/mL and 350 mgI/mL, respectively. Statistical data are shown, there were no significant differences in the CT values of the middistal left anterior descending (LAD) and the distal left circumflex (LCX) of three groups ( P>0.05), and the CT values of the other segments in group A were higher than those in group B and C ( P<0.05). There were no significant differences in the noise values of the middistal LAD, LCX and right coronary artery (RCA) in the three groups ( P>0.05). There were no significant differences in signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and subjective scores among the three groups ( P>0.05). The radiation dose of group A was significantly lower than that of group B and group C ( P<0.05). In conclusion, low dose combined with low concentration contrast agent can be used in 320-row coronary CTA, which is conducive to reducing the harm of X-ray radiation and high concentration of contrast agent to patients. Reference | Related Articles | Metrics

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The Relationship between Sinus CT Score, EOS Count and CRSwNP Patients Complicated with AAHR XIE Huanqing, XU Guozhen IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (3): 453-458.   DOI: 10.7517/issn.1674-0475.211142 Abstract （189）   HTML （3）    PDF （934KB）（59）       Knowledge map    Save This study investigated the value of sinus CT score and eosinophil (EOS) count in the diagnosis of chronic rhinosinusitis with nasal polyps (CRSwNP) complicated with asymptomatic airway hyperresponsiveness (AAHR). A clinical study was conducted on 127 confirmed CRSwNP patients, according to whether the patients were accompanied by AAHR, they were divided into observation group (71 cases) and CRSwNP patients without airway hyperresponsiveness (56 cases) as control group. Performed the sinus CT three-dimensional reconstruction and scoring, and detected the levels of EOS in nasal polyps and peripheral blood of the two groups. The expression levels of EOS in nasal polyps and peripheral blood tissues of the observation group were higher than those of the control group ( P<0.05). The AUC value of EOS in nasal polyps to diagnose CRSwNP patients complicated with AAHR was 0.852, and in peripheral was 0.821. The CT scores of olfactory cleft and ethmoid sinus in the observation group were significantly higher than those in the control group ( P<0.05). There was no significant difference in maxillary sinus CT scores between the observation group and the control group ( P>0.05). The AUC value of olfactory fissure CT score in the diagnosis of CRSwNP patients complicated with AAHR was 0.761, and of ethmoid sinus was 0.864. CRSwNP patients complicated with AAHR are serious. The detection of EOS expression and sinus CT scores have a certain value in judging whether CRSwNP patients complicated with AAHR. Reference | Related Articles | Metrics

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The Value of SWE Combined with Urinary Exfoliative Cytology Detection in the Identification of Bladder Urothelial Carcinoma Grades YANG Beibei, XU Jinzhi, ZHENG Xiaoju IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 53-58.   DOI: 10.7517/issn.1674-0475.221022 Abstract （174）   HTML （5）    PDF （833KB）（59）       Knowledge map    Save This study investigated the application of shear wave elastography (SWE) combined with the urinary exfoliated cells detection in the diagnosis and grade judgment of bladder urothelial carcinoma. 87 patients with bladder urothelial carcinoma confirmed by pathological examination were selected as the case group, and 85 patients with simple urothelial hyperplasia were selected as the control group. The routine ultrasound characteristic parameters, SWE parameters, and fluorescence in situ hybridization (FISH) detection results of urinary exfoliated cells were compared between the two groups of patients, and the case groups were stratified according to the pathological grading results. Compared the ultrasound parameters of the case group and the control group, the rich lesion blood flow characteristics, the internal echo inhomogeneous rate, the multiple tumor lesion rate, and the surface roughness rate in the case group were significantly higher than those in the control group ( P<0.05). The lesion SWE parameters Emax, Emean and Emin of the case group were significantly higher than those of the control group ( P<0.05), the positive rate of FISH in the case group was higher than that in the control group ( P<0.05). In patients with high-grade bladder urothelial carcinoma, the blood flow enrichment rate and the surface feature roughness rate of lesions were significantly higher than those in patients with low-grade lesions ( P<0.05). The SWE parameters Emax, Emean and Emin of patients with high-grade bladder urothelial carcinoma were significantly higher than those of patients with low-grade lesions ( P<0.05). The positive rate of FISH in patients with high-grade bladder urothelial carcinoma was higher than that in low-grade patients ( P<0.05). The detection of SWE and urinary exfoliated cells has high clinical value in the diagnosis of bladder urothelial carcinoma and the assessment of lesion grade. Reference | Related Articles | Metrics

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The Diagnostic Value of Ultrasound-guided Thyroid Fine-needle Aspiration Biopsy for PTMC WANG Jing, LIU Ying, CUI Quanzhe, ZHOU Yang IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (6): 1423-1427.   DOI: 10.7517/issn.1674-0475.220714 Abstract （140）   HTML （3）    PDF （691KB）（58）       Knowledge map    Save This study investigated the diagnostic value of ultrasound-guided thyroid fine-needle aspiration biopsy (US-FNAB) for papillary thyroid microcarcinoma (PTMC). A total of 203 patients (203 nodules) with thyroid micronodules confirmed by pathological examination were selected. All patients underwent US-FNAB examination. The relationship between thyroid micronodules with different cytological characteristics and Bethesda classification of thyroid was analyzed. The pathological examination results were used as the gold standard to analyze the value of US-FNAB in the diagnosis of PTMC. According to the Bethesda classification of thyroid, there were 0 nodules of class Ⅰ, 33 nodules of class Ⅱ, 49 nodules of class Ⅲ, 51 nodules of class Ⅳ, 40 nodules of class Ⅴ, and 30 nodules of class Ⅵ. The proportion of solid nodules, hypoechoic nodules, nodules with blurred borders, and nodule aspect ratio≥1 in malignant thyroid nodules was higher than that in benign nodules ( P<0.05); US-FNAB The sensitivity and specificity of differential diagnosis of PTMC and benign thyroid nodules were 85.29% and 91.11%; the sensitivity and specificity of ultrasound in differential diagnosis of PTMC and benign thyroid nodules were 75.00% and 83.70%.The diagnostic value of US-FNAB for PTMC is higher than that of ultrasonography, and it is of great significance for the formulation of clinical individualized treatment plans. Reference | Related Articles | Metrics

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The Sand Bed Rehabilitation Training Effect and Lateral Collateral Ligament Injury of Ankle Evaluation Through High-frequency Ultrasound Image LIU Yunwu, GUO Qiming, HE Yinghui, SUN Fenghao, LI Shihao IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (3): 665-669.   DOI: 10.7517/issn.1674-0475.211129 Abstract （248）   HTML （2）    PDF （224KB）（57）       Knowledge map    Save This article discussed the clinical value of high-frequency ultrasound in the diagnosis of ankle lateral collateral ligament injury and the rehabilitation training of sand bed. 120 patients with ankle lateral collateral ligament injury treated were selected as the research subjects. Among them, 78 patients were treated with conservative rehabilitation therapy combined with sand bed rehabilitation training (conservative group), and 42 patients were treated with surgery combined with sand bed rehabilitation training (operation group). There was no significant difference in the degree of injury of the anterior talofibular ligament diagnosed by high-frequency ultrasound compared with MRI in the conservative group ( P>0.05). There were 34 cases patients with anterior calcaneofibular ligament injury in the conservative group, and there was no significant difference in diagnosis of anterior calcaneal and fibular ligament injury between high-frequency ultrasonography and MRI ( P>0.05). There was no significant difference in the degree of injury of the anterior talofibular ligament and anterior calcaneofibular ligament in the high-frequency ultrasound diagnosis665of the operation group and intraoperative findings ( P> 0.05); high-frequency ultrasound evaluation of the ankle joint function of the cured group was significantly better than that of the effective group ( P<0.05). There is little difference between high-frequency ultrasound in diagnosing lateral ankle collateral ligament injury and MRI diagnosis and intraoperative findings. High-frequency ultrasound has certain clinical value as a preoperative diagnosis of ankle lateral collateral ligament injury and judgment of ankle function recovery. Reference | Related Articles | Metrics

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Sensitivity and Accuracy Analysis of Energy Spectrum CT for the Diagnosis of Hepatocellular Carcinoma WANG Xueling, YUAN Qingling, YANG Juan IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (6): 1339-1342.   DOI: 10.7517/issn.1674-0475.220720 Abstract （161）   HTML （10）    PDF （610KB）（56）       Knowledge map    Save This study investigated the value of spectral CT in the diagnosis of hepatocellular carcinoma. 110 cases of liver space occupying lesions were selected, all of them were given spectral CT and spiral CT examination. Among the 110 patients, 88 were diagnosed as hepatocellular carcinoma and 22 as focal nodular hyperplasia. The sensitivity, accuracy and negative predictive value of spectral CT in the diagnosis of hepatocellular carcinoma were significantly higher than those of spiral CT ( P<0.05). In tumor diameter <3 cm, the detection rate of spectral CT was higher than that of spiral CT ( P<0.05). The ratio of iodine uptake (IUR) in arterial phase, IUR in portal vein phase, standardized iodine concentration (NIC) in arterial phase, slope of energy spectrum curve (S) in arterial phase and S in portal vein phase of hepatocellular carcinoma were significantly lower than those in focal nodular hyperplasia ( P<0.05). The area under the ROC curve (AUC) of arterial IUR, portal IUR, arterial NIC, arterial S and portal S in the diagnosis of hepatocellular carcinoma were 0.846, 0.767, 0.753, 0.811 and 0.715, respectively ( P<0.05), the AUC of the combined diagnosis of the above parameters was 0.921, and the sensitivity and specificity were 90.00% and 88.00%, respectively. Energy spectrum CT has good application value in the diagnosis of hepatocellular carcinoma and is worthy of clinical use. Reference | Related Articles | Metrics

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Correlation Analysis of Intracranial Vascular Plaque Parameters Based on HR-MRI and Prognosis of Patients with Early-onset and Re-onset Cerebral Infarction ZHU Tong, WU Yanyun, CHEN Yuxian IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (6): 307-313.   DOI: 10.7517/issn.1674-0475.230701 Abstract （79）   HTML （7）    PDF （854KB）（56）       Knowledge map    Save The differences of intracranial vascular plaque parameters between high-resolution magnetic resonance imaging (HR-MRI) in elderly patients with primary and recurrent cerebral infarction were compared, and the relationship between the characteristic parameters of intracranial vascular plaque and the prognosis of patients was discussed. A total of 179 elderly patients with cerebral infarction were retrospectively selected. All patients underwent HR-MRI examination before treatment. According to the cause of hospitalization, the patients were divided into primary group and recurrent group. The differences of HR-MRI intracranial vascular plaque parameters between the two groups were compared. According to the clinical outcomes, the patients were divided into good prognosis group and poor prognosis group. Univariate and multivariate Logistic regression analysis were used to analyze the relationship between HR-MRI intracranial vascular plaque parameters and other factors and the prognosis of patients with cerebral infarction. The receiver operating characteristic (ROC) curve was used to analyze the efficacy of HR-MRI intracranial vascular plaque parameters in predicting the poor prognosis of patients with cerebral infarction. The results indicate there was no significant difference in plaque remodeling and eccentricity index between the initial and recurrent cerebral infarction groups ( P>0.05). There were significant differences in intracranial vascular plaque area, plaque load, plaque hemorrhage ratio and plaque enhancement degree between the two groups ( P<0.05). Univariate and multivariate results showed that recurrent cerebral infarction, infarct size, increased NIHSS score, increased plaque load, and intraplaque hemorrhage were independent influencing factors for poor prognosis in patients with cerebral infarction. The AUC of plaque burden, intraplaque hemorrhage, plaque enhancement and predictive probability based on HR-MRI in predicting the risk of poor prognosis in patients with cerebral infarction were 0.658, 0.604 and 0.616, respectively, and the specificities were 77.8%, 76.9% and 82.9%, respectively. The combined prediction AUC was 0.727, the sensitivity was 79.0%, and the specificity was 53.8%. The above findings the characteristics of intracranial vascular plaques in patients with primary and recurrent acute cerebral infarction are different. The characteristics of intracranial vascular plaques are closely related to the prognosis of patients with cerebral infarction. The characteristics of intracranial vascular plaques in cerebral infarction by HR-MRI are helpful to predict the prognosis of patients with cerebral infarction. Reference | Related Articles | Metrics

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Changes of Fragmented QRS Wave, Echocardiography and 2D-STI Parameters in Patients with AMI after PCI WEI Wei, LAN Feifei, QIU Yuyu, QIN Honghui IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (6): 1343-1348.   DOI: 10.7517/issn.1674-0475.220809 Abstract （164）   HTML （4）    PDF （868KB）（55）       Knowledge map    Save This study investigated the relationship between fragmented QRS complex in electrocardiogram, echocardiography, two-dimensional speckle tracking (2D-STI) and left ventricular remodeling in patients with acute myocardial infarction (AMI). A total of 113 patients who were diagnosed with AMI and received percutaneous coronary intervention (PCI) were selected for clinical research. According to whether the patients had left ventricular remodeling within 12 months after PCI, they were divided into a remodeling group of 41 cases and a non-remodeling group of 72 cases. The dynamic electrocardiogram fragmentation QRS complex at admission, echocardiogram and 2D-STI indexes at 6 months after PCI were compared between the two groups, and the relationship between the above indexes and left ventricular remodeling was analyzed by Logistic regression model. The positive rate of fragmented QRS complex in the remodeling group was higher than that in the non-remodeling group ( P<0.05). The measured values of left ventricular end-diastolic volume (LVEDV), interventricular septal thickness (IVST) and left ventricular posterior wall thickness (LVPWT) in the remodeling group were significantly higher than those in the non-remodeling group ( P<0.05). The measured values of left ventricular ejection fraction (LVEF) and left ventricular end-systolic volume (LVESV) in the remodeling group were lower than those in the non-remodeling group. The measured values of overall circumferential strain (CS), overall radial strain (RS), and longitudinal strain (LS) in the remodeling group were lower than those in the non-remodeling group ( P<0.05). Complicated hypertension, coronary artery disease branch number ≥3, increased IVST, increased LVPWT, and positive fragmented QRS complex were positively correlated with left ventricular remodeling in patients with AMI after PCI ( P<0.05). The LVEF, CS, RS, LS measured values were negatively correlated with left ventricular remodeling in patients with AMI after PCI ( P<0.05). Observation of ECG, echocardiography and 2D-STI after PCI in patients with AMI has certain clinical value in evaluating whether patients have left ventricular remodeling after operation. Reference | Related Articles | Metrics

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Characteristics Analysis of MRI in the Diagnosis of Invasive Pituitary Adenomas and Effect Observation of the Surgical Effect of Endoscopic Double Nostril Approach WANG Yanjun, ZHAO Decai, SUN Zheng, ZHANG Peng, LU Lei IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 90-95.   DOI: 10.7517/issn.1674-0475.221014 Abstract （179）   HTML （5）    PDF （823KB）（55）       Knowledge map    Save This study investigated the magnetic resonance imaging (MRI) features of invasive pituitary adenomas and the clinical effects of endoscopic bilateral nostril approach. 35 patients with invasive pituitary adenoma were selected as the invasive group, and 25 patients in the same period with non-invasive pituitary adenoma were selected as the non-invasive group. The differences of MRI imaging parameters between the two groups were compared. Both groups were treated by endoscopic double-nostril approach, and the surgical effect and changes of serum growth hormone and prolactin levels of patients were observed. The invasive group was mainly characterized by large adenoma and giant adenoma, while the non-invasive group was mainly characterized by microadenoma ( P<0.05). There was no significant difference in the composition of prolactin (PRL) adenoma, adrenocorticotropic hormone (ACTH) adenoma, growth hormone (GH) adenoma, mixed adenoma and non-functional pituitary adenoma between the invasive group and the non-invasive group ( P>0.05). Patients in the invasion group mainly showed slow rising time-signal intensity curve and plateau time-signal intensity curve, while patients in the non-invasion group mainly showed rapid rising time-signal intensity curve ( P<0.05). The serum levels of growth hormone and prolactin in the two groups at 1 week and 1 month after operation were both significantly lower than those before operation ( P<0.05). There was no significant difference in the overall clinical efficacy between the invasive group and the non-invasive group ( P>0.05). The tumor lesion of invasive pituitary adenoma was generally larger than that of non-invasive pituitary adenoma. The time-signal intensity curve of MRI was mainly of slow-rising type and plateau type, and endoscopic double-nostril approach for the treatment of invasive pituitary adenoma and non-invasive pituitary adenoma had a good effect. Reference | Related Articles | Metrics

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Research on Prediction of Esophagogastric Variceal Bleeding in Cirrhotic Patients by Preoperative Portal Vein CTA ZHAO Yongchang, XU Jing, CHEN Shixin, MA Yonggang IMAGING SCIENCE AND PHOTOCHEMISTRY    2023, 41 (1): 164-168.   DOI: 10.7517/issn.1674-0475.221031 Abstract （175）   HTML （3）    PDF （554KB）（54）       Knowledge map    Save This study evaluated the value of preoperative portal vein CT angiography (CTA) in predicting esophagogastric variceal bleeding in patients with liver cirrhosis. 90 patients with cirrhotic esophagogastric varices bleeding were selected as bleeding group, and 90 cirrhotic patients with esophagogastric varices without bleeding were selected as control group. Compared the preoperative CTA test results of the two groups, which including the diameter of main portal vein (MPV), splenic vein (SPV) and left gastric vein (LGV). The concentrations of serum total bilirubin (TBIL), serum alkaline phosphatase (ALP) and prothrombin activity (PTA) were compared between the two groups. Analyzed the statistically significant indexes which was valuable in predicting gastric variceal bleeding. The measured values of MPV diameter, SPV diameter and LGV diameter in the bleeding group were significantly higher than those in the control group( P<0.05). The AUC values of MPV diameter, SPV diameter and LGV diameter for predicting bleeding were 0.800, 0.660 and 0.743, respectively. There was no significant difference in TBIL and ALP between bleeding group and control group ( P>0.05). The PTA in bleeding group was higher than that in control group, and the difference was statistically significant ( P<0.05). Logistic regression model analysis showed that the increase of MPV diameter, SPV diameter, LGV diameter and PTA were the risks of esophagogastric variceal bleeding ( P<0.05). Preoperative CTA examination of the diameters of MPV, SPV and LGV is of high value in predicting esophagogastric variceal bleeding in patients with liver cirrhosis, and the three parameters are closely related to esophagogastric variceal bleeding. Reference | Related Articles | Metrics

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The Role of Contrast-enhanced Ultrasound in Puncture Biopsy of Peri-pulmonary Lesions ZHU Pengfei, HE Ying IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (6): 1349-1353.   DOI: 10.7517/issn.1674-0475.220622 Abstract （134）   HTML （8）    PDF （1001KB）（54）       Knowledge map    Save This paper investigated the application value of ultrasound and contrast-enhanced ultrasound-guided coarse needle biopsy in peripheral pulmonary lesions. 158 patients with peripheral pulmonary lesions diagnosed by CT or MRI were selected as the research objects. They were divided into conventional ultrasound group and contrast-enhanced ultrasound group. The conventional ultrasound group underwent puncture biopsy under the guidance of ordinary ultrasound, while the contrast-enhanced ultrasound group underwent ultrasound contrast examination on the basis of ordinary ultrasound, and then percutaneous puncture biopsy under its guidance. The puncture success rate, the display rate of intrafocal necrosis, the diagnostic accuracy of subtype (classification), the positive rate of epidermal growth factor receptor (EGFR) and the complications after puncture were compared between the contrast-enhanced ultrasound group and the conventional ultrasound group. According to the pathological results, the success rate of contrast-enhanced ultrasound group (100%) was higher than that of conventional ultrasound group (90%), P<0.05. The display rate of necrosis in the contrast-enhanced ultrasound group (46%) was much higher than that in the conventional ultrasound group (21%), P<0.05. The diagnostic accuracy rate of subtype (classification) in the contrast-enhanced ultrasound group (96%) was slightly higher than that in the conventional ultrasound group (94%),the difference was not statistically significant ( P>0.05). The positive rate of EGFR in the contrast-enhanced ultrasound group (32%) was lower than that in the conventional ultrasound group (35%),the difference was not statistically significant ( P>0.05). Ultrasound and contrast-enhanced ultrasound-guided puncture are of great value in the diagnosis of peripheral lung lesions, and contrast-enhanced ultrasound has more advantages over conventional ultrasound in the relationship between the lesion and the surrounding tissue structure and the blood flow inside the lesion, which can effectively improve the success rate of puncture. Reference | Related Articles | Metrics

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Comparison of MSCT Plain Scan and Enhanced Scan in Determining the Properties of Pulmonary Nodules SUN Jingxi, SHI Yibing, WANG Xiuling IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (6): 1428-1432.   DOI: 10.7517/issn.1674-0475.220611 Abstract （241）   HTML （7）    PDF （633KB）（54）       Knowledge map    Save The purpose of this paper was to analyze the difference between the multi-slice spiral computed tomography (MSCT) chest plain and contrast-enhanced scans in judging the nature of pulmonary nodules. The clinical data and MSCT chest plain scan and MSCT enhanced scan images of 125 patients with pulmonary nodules were retrospectively analyzed, and the pulmonary nodule images under MSCT plain scan and MSCT enhanced scan were analyzed. The results showed that the display rate of lobulation sign, pleural stretch sign, vascular bundle sign and vacuole sign under enhanced scan was significantly higher than that of MSCT plain scan ( P<0.05). The enhanced CT value and CT value increment of benign nodular lesions [(56.84±11.36) Hu and (25.67±13.65) Hu, respectively] were lower than those of malignant nodular lesions [(79.52±12.32) Hu and (48.95±12.35) Hu, respectively, P<0.05]. The diagnostic sensitivity, specificity and accuracy of MSCT plain scan were 65.96%, 67.95% and 67.20%, respectively. The diagnostic sensitivity, specificity and accuracy of MSCT enhanced scan were 80.85%, 80.77% and 80.80%, MSCT enhanced scan was closer to pathological results. Both plain MSCT scan and MSCT enhanced scan have good clinical value in judging the nature of pulmonary nodules, but MSCT enhanced scan has more prominent diagnostic value for the nature of pulmonary nodules. Reference | Related Articles | Metrics

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The Relationship between the Characteristics of CMBs and ACVS Based on SWI and the Prognosis of Patients with Acute Cerebral Infarction CHEN Pianpian, WANG Yaoguang, SHEN Chunyun, CAI Linjiang, CHEN Shaoqun, CHEN Hongen, GAO Junjie IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (6): 1396-1401.   DOI: 10.7517/issn.1674-0475.220619 Abstract （143）   HTML （5）    PDF （1015KB）（54）       Knowledge map    Save This study investigated the relationship between cerebral microbleeds (CMBs) and asymmetric cortical vein sign (ACVS) detected by susceptibility-weighted imaging (SWI) and the prognosis of patients with acute cerebral infarction (ACI). A total of 87 patients diagnosed with ACI and receiving intravenous thrombolysis were selected as the research subjects. All subjects underwent SWI scanning. According to the modified Rankin scale (mRS), the patients were divided into good prognosis (58 cases in the good group), poor prognosis (29 cases in the poor group) two groups. The detection rates of CMBs and ACVS were compared between the two groups, and the receiver operating characteristic (ROC) curve method was used to explore the prediction of the two indicators in the prognosis of patients after ACI intravenous thrombolysis. aspects of the role. The results showed that the detection rate of CMBs and ACVS in the good group was significantly lower than that in the poor group ( P<0.05). Logistic model results showed that higher baseline NIHSS score, higher NIHSS score at 24 h of thrombolysis, combined hypertension, severe middle cerebral artery stenosis, CMBs, and ACVS were independent risk factors for poor prognosis in ACI patients ( P<0.05). Decreased ASPECTS infarct area score was an independent risk factor for poor prognosis in ACI patients ( P<0.05). SWI can early detect the characteristics of CMBs and ACVS after intravenous thrombolysis in ACI patients, and can evaluate the risk of poor prognosis of patients. Reference | Related Articles | Metrics