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    The Role of Contrast-enhanced Ultrasound in the Detection of Carotid Intraplaque Neovascularization in Coronary Heart Disease and Its Relationship with the Expression of Serum Hcy
    SUN Xiang, TAN Jie
    IMAGING SCIENCE AND PHOTOCHEMISTRY    2022, 40 (6): 1402-1406.   DOI: 10.7517/issn.1674-0475.220725
    Abstract143)   HTML3)    PDF (817KB)(713)       Save
    This study investigated the role of contrast-enhanced ultrasonography (CEUS) in the detection of carotid plaque neovascularization (IPN) in coronary artery disease and its relationship with the expression of serum homocysteine (Hcy) and blood lipids. A total of 167 patients with stable coronary heart disease (CAD) and carotid plaque (thickness ≥1.5 mm) were selected as the research subjects. IPN was examined by CEUS, and the patients were divided into IPN group ( n=82) and non-IPN group ( n=85). The baseline data, carotid ultrasound characteristics, blood lipid metabolism indexes, serum Hcy levels, and the incidence and occurrence time of major adverse cardiovascular events (MACE) were compared between the two groups. The results showed that the maximum plaque thickness in the IPN group was higher than that in the non-IPN group [(3.23±1.07) mm vs (2.85±0.87) mm, P<0.05]. There was no significant difference in TC, TG, HDL-C and LDL-C between the two groups ( P>0.05). The serum Hcy level in the IPN group was higher than that in the non-IPN group ( P<0.05). The overall incidence of MACE was 7.19% (12/167). The Kaplan-Meier survival curve of patients’ MACE showed that the occurrence time of MACE in patients with IPN was earlier than in non-IPN group at follow-up ( P<0.05). This study suggests that IPN, maximum plaque thickness and serum Hcy levels may be predictors of adverse cardiovascular events in patients with coronary heart disease.
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    Research Progress of the Bottom Anti-reflective Coating for Photoresist
    WANG Kuan, LIU Jingcheng, LIU Ren, MU Qidao, ZHENG Xiangfei, JI Changwei, LIU Xiaoya
    Imaging Science and Photochemistry    2016, 34 (2): 123-135.   DOI: 10.7517/j.issn.1674-0475.2016.02.123
    Abstract1722)      PDF (3870KB)(5088)       Save

    With the rapid development of the micro-electronics industry, lithography technology has been moving forward to a higher resolution. Bottom anti-reflective coating has attracted great attention of researchers in terms of effectively eliminating the standing wave effect and the notching effect, improving the critical dimension uniformity and the patterning resolution. In this article, the photoresists and photolithography technique, and the classification, basic principle, etching process and development situation of the bottom anti-reflective coating are briefly reviewed. The latest research progress of the bottom anti-reflective coating is summarized in detail, especially the application of developable bottom anti-reflective coating in photoresist. Finally, the prospect and research directions of bottom anti-reflective coating in the future are also introduced.

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    Evolution and Progress of I-Line Photoresist Materials
    ZHENG Jin-hong
    Imaging Science and Photochemistry    2012, 30 (2): 81-90.   DOI: 10.7517/j.issn.1674-0475.2012.02.81
    Abstract2680)      PDF (1204KB)(2972)       Save
    Novolak-diazonaphthoquinone photoresists have been widely used in g-line、i-line lithography for its high performance. Although g-line and i-line photoresists are both consisted of novolak resin and diazonaphthoquinone photoactive compounds,in order to fit i-line exposure wavelength and seeking for higher resolution, novolak resin and photoactive compounds(PAC) both have difference in structure from g-line to i-line.In i-line resist,the o-o'bonding content of resin is higher, the esterfication of PAC is higher, the proximity of DNQ groups is distant. Dissolution promoter is an important component of i-line resists, some phenolic additives were very useful to control the dissolution behavior.
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    Controlling and Application of the Triplet Excited State of Organic Chromphores
    WANG Zhijia, CHEN Kepeng, LIU Ya, ZHAO Jianzhang, ZAFAR Mahmood, JI Wei, HAN Keli
    Imaging Science and Photochemistry    2017, 35 (3): 211-232.   DOI: 10.7517/j.issn.1674-0475.2017.03.211
    Abstract1241)      PDF (8653KB)(2120)       Save

    The recent development of controlling of the triplet excited state of organic chromophores was summarized. Controlling the triplet excited state is very useful, by which various functional organic compounds can be developed. For instance, the activatable PDT photosensitizers, phosphorescent molecular probes, and can be applied in photoswitchable triplet-triplet annihilation (TTA) upconversion. However, by comparison to the controlling of singlet excited state (fluorescence), the study on the controlling of the triplet excited state is rare. Recently there are some reports on triplet state switching by supramolecular or covalent modification methods, based on photophysical processes such as Förster resonance energy transfer (FRET), triplet triplet energy transfer (TTET), photo-induced electron transfer (PET), etc. These reports show that controlling of the triplet excited state is very different from controlling of the singlet excited state. For example, usually the singlet excited state can be quenched by PET effect, but the triplet excited state can not be quenched by PET effect in many cases. This review article summarizes the development of triplet state switching, and will be useful for the molecular design concerning the controlling and application of triplet excited state in functional organic compounds.

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    Analysis of the Application Value of Dual-source CT and MRI in the Diagnosis of Gouty Arthritis
    LI Chunlei, QING Guangjun, WANG Rongfen, PENG Ke
    Imaging Science and Photochemistry    2020, 38 (2): 344-349.   DOI: 10.7517/issn.1674-0475.191003
    Abstract304)      PDF (624KB)(705)       Save
    100 patients with gouty arthritis who were treated in our hospital from May 2017 to May 2019 were enrolled. All patients underwent dual-source CT and MRI. In this study, we compared the positive diagnostic rate and the diagnostic sensitivity of dual-source CT and MRI, as well as the image differences in two methods(including tophus, joint bone damage, articular cartilage damage, joint effusion, peripheral edema, synovial damage and urate crystal). The aim was to explore the value of dual-source CT and MRI in the diagnosis of patients with gouty arthritis. The results showed that the positive rate and diagnostic sensitivity of dual-source CT were higher than that of MRI, and the difference was statistically significant. Dual-source CT had a higher detection rate for tophus and bone destruction than MRI, and the difference was statistically significant. Dual-source CT has high specificity in detecting urate crystals. In examination of joint effusion, synovium and cartilage change, MRI has higher detection rates than dual-source CT, and the difference was statistically significant. The above results indicate that dual-source CT is specific in diagnosing urate crystals. The application value of dual-source CT in the diagnosis of gouty arthritis is higher than MRI.
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    Construction and Application of Biomimetic Photoresponsive Smart Nanochannels
    XIAO Kai, WEN Liping, JIANG Lei
    Imaging Science and Photochemistry    2017, 35 (4): 337-348.   DOI: 10.7517/j.issn.1674-0475.2017.04.001
    Abstract698)      PDF (2862KB)(1689)       Save

    In living organisms, many biological processes are inextricably linked with light, such as the photosynthesis systems and rhodopsin. Hence, construction of light-sensitive biomimetic nanochannels, which can realize the functions of cells and other membrane structures with high degree of spatial and temporal control, is particularly attractive and challenging. In this review, we mainly summarize the construction and applications of photoresponsive nanochannels on the basis of various photoresponsive materials. Furthermore, the review highlights some of the most recent applications of photoresponsive nanochannels in separation, energy conversion and storage, drug delivery and so on.

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    Effect of Pressure on Morphology and Crystallinity of the Perovskite Thin Film
    KONG Xiangbin, CHEN Yongzhen, LI Zhiyi, LIU Yanwei, WEI Xiaofang, LIU Jianjun, WANG Ruifang, WANG Ying
    Imaging Science and Photochemistry    2017, 35 (5): 749-757.   DOI: 10.7517/j.issn.1674-0475.2017.04.035
    Abstract634)      PDF (4424KB)(1042)       Save

    A novel and simple method to control the crystallization process during the formation of perovskite thin films is critical for optimizing the device fabrication process and constructing high efficiency perovskite solar cells. In this article, a method of adjusting the vacuum was used to effectively control the crystallization process. Furthermore, the role of pressure and its influence upon perovskite crystal growth, film formation and device performance were systematically investigated. The crystallinity and morphology of the perovskite thin film were characterized by scanning electron microscope (SEM), ultraviolet-visible absorption spectra (UV-Vis) and X-ray diffraction (XRD). Based on the structure of Glass/ITO/PEDOT:PSS/CH3NH3PbI3/PCBM/Al, the performance of the device corresponding to the different pressure was studied. The results indicate that the decreased pressure can enhance the crystallinity of the perovskite film obviously, and improve the surface coverage by reducing the amount of holes. At the same time, the short circuit current, filling factor and photoelectric conversion efficiency of the device are all improved with the pressure decreasing. A 19% higher power conversion efficiency of 12.36% was achieved in comparison to the device fabricated by traditional method, which exhibited just 10.38% efficiency.

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    Application Value in Diagnosis and Prognosis Evaluation of Echocardiography and Dynamic Electrocardiogram Examination in Patients with Acute Myocardial Infarction
    DING Minxia, TANG Xiangrui, ZHAO Yan
    Imaging Science and Photochemistry    2020, 38 (2): 248-252.   DOI: 10.7517/issn.1674-0475.190903
    Abstract338)      PDF (563KB)(652)       Save
    To investigate the application value in diagnosis and prognosis evaluation of echocardiography and dynamic electrocardiogram examination in patients with acute myocardial infarction(AMI), 100 AMI patients admitted and diagnosed in our hospital from June 2016 to June 2018 were selected as the observation group, and 100 patients without coronary heart disease in the same period were selected as the control group. Cardiac death was the end point of AMI, the observation group was divided into death group ( n=15) and survival group ( n=85). All patients were underwent echocardiography examination by Philips IU-Elite and EPIQ5 color Doppler ultrasound, as well as the dynamic electrocardiogram examination by the standard 12 lead Holter performed with DMS-300 4A electrocardiograph. The changes of heart rate turbulence index[TO, TS], heart rate variability index[SDNN, QTd, QTcd], and cardiac function index[LVEDD, LVEF] levels in each group were compared. The results showed that the TO, QTd, QTcd and LVEDD in the observation group were significantly higher than those in the control group, while TS, SDNN and LVEF were significantly lower than those in the control group ( P<0.05). TS and SDNN in death group were significantly lower than those in survival group ( P<0.05). The TO of death group was higher than that of survival group, while the QTd, QTcd, LVEF and LVEDD of death group were lower than those of survival group, but there was no significant difference ( P>0.05). This study demonstrated that, HRT in patients with AMI decreased or even disappeared, HRV and LVEF decreased, LVEDD and QTd increased, and the QT interval prolonged. The echocardiography combined with dynamic electrocardiogram examination has important clinical value in the diagnosis and prognosis evaluation of patients with AMI.
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    Imaging Science and Photochemistry    1993, 11 (1): 96-96.   DOI: 10.7517/j.issn.1674-0475.1993.01.96
    Abstract701)      PDF (142KB)(1152)       Save
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    Common Problems of Confocal Laser Scanning Microscopy on Colocalization
    WANG Juanjuan, WEI Xuehong
    Imaging Science and Photochemistry    2018, 36 (6): 532-538.   DOI: 10.7517/issn.1674-0475.180301
    Abstract1009)      PDF (3413KB)(1291)       Save
    The colocalization of fluorescence is a common technique in the biological imaging. In order to get true results of colocalization, we describe the following four aspects in detail, which are common problems of colocalization by Zeiss LSM880 (confocal laser scanning microscope, CLSM), as well as the solutions. First, how to use CLSM for colocalization experiments. Second, how to conduct colocalization analysis. Third, how to evaluate colocalization. Fourth, how to determine the colocalization results. In the colocalization study, we can get the accurate and reliable colocalization analysis results if we take the images strictly following the basic requirements of the colocalization experiment and analyse them according to the above methods.
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    Progresses on Sensitization of Cationic Photoinitiators
    ZHANG Hong, LI Jian-xiong, LIU An-hua
    Imaging Science and Photochemistry    2013, 31 (1): 69-78.   DOI: 10.7517/j.issn.1674-0475.2013.01.009
    Abstract2144)      PDF (1060KB)(3765)       Save
    The curing rate and quantum efficiency of cationic photoinitiators are relatively low because the UV absorption of the photoinitiators ranges from 250 nm to 300 nm normally and does not match with the wavelength of light from UV light sources. To make the absorption red-shift, many efforts have been devoted onto the photosensitization of the photoinitiators. The achievements on the sensitization of the cationic photoinitiators have been summarized here. The sensitization is mainly based on the mechanisms as energy transfer, oxidation of free radical,electron transfer via exciplexes and addition fragmentation reaction. The methods adopted for the sensitization include adding photosensitizer,expanding molecular conjugation and attaching chromophore. The development of the photoinitiators and photosensitizers has been outlined and the applications of novel cationic photoinitiators and photosensitizers have been forecasted.
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    Synthesis of GelMA/PEGDA Hydrogel by UV Photopolymerization
    WANG Yihu, ZHANG Bing, MA Ming, LU Weipeng, WANG Jianing, GUO Yanchuan
    Imaging Science and Photochemistry    2017, 35 (4): 574-580.   DOI: 10.7517/j.issn.1674-0475.2017.04.019
    Abstract1996)      PDF (3220KB)(2347)       Save

    To avoid the thermolability of physically cross-linked gelatin hydrogel and toxicity of chemically cross-linked gelatin hydrogel, double bonds were introduced to gelatin molecule chain by acrylation, and then gelatin methacrylamide(GelMA) and polyethylence glycol diacrylate(PEGDA) were cross-linked to hydrogels by the UV photopolymerization. The relationship between the quantity of methacrylic anhydride(MA) and degree of modification and physicochemical properties of GelMA/PEGDA were investigated and analyzed. The result indicated that more radicals could be released in the system when more PEGDA were added. So the activity and extent of crosslinking reaction was increased and hydrogel with much denser 3D network was formed. Cross-linked GelMA/PEGDA hydrogel have better thermal stability than cross-linked GelMA at 37 ℃. Cross-linked GelMA/PEGDA hydrogel can be used as scaffold materials of tissue engineering.

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    Effects of Preparing Conditions on Structure and Electrical Properties of AZO Films
    ZHANG Tian-bao, LI Jin-pei
    Imaging Science and Photochemistry    2009, 27 (6): 452-461.   DOI: 10.7517/j.issn.1674-0475.2009.06.452
    Abstract1124)      PDF (729KB)(3923)       Save
    Transparent conducting aluminum-doped zinc oxide (AZO) thin films have been prepared by the sol-gel method on glass substrate. In this paper,the effect of two different ways of heat-treatment and anneal on structure and properties of thin films was compared and the influence of doping concentration and annealed temperature on structure and properties of AZO films was studied. It was found that high temperature,layer by layer annealing and doping of aluminum are all propitious to the AZO films with high crystalline and preferential c-axis orientation;and on the other hand high temperature and layer by layer annealing are demonstrated to be beneficial to the crystallite size enhancement,whereas which is hold back by doping of aluminum;in addition,the regular change of the electricity properties of thin films was revealed with the change of annealing temperature and doping concentration of aluminum. By analyzing the process of crystal growth inside AZO thin films,the conclusion was drawn in this paper that the difference of crystalline,crystallite orientation and crystallite size of AZO films was mainly caused by preparing conditions and growth habits of AZO crystallite.
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    Preparation of the Photosensitive Amphiphilic Compound Having an Azobenzene Group and the Effect of the Light Illumination on Its Properties
    CHAO Junjie, JIANG Xiaoming
    Imaging Science and Photochemistry    2020, 38 (4): 615-620.   DOI: 10.7517/issn.1674-0475.200402
    Abstract331)      PDF (2200KB)(549)       Save
    A photosensitive amphiphilic compound (AS), which has an azobenzene group, was synthesized using p-methylaniline and phenol as the start material in four steps. Its structure was characterized by 1H NMR. The photoisomerization of the compound was studied by ultraviolet absorption spectroscopy. The results show that the structure of AS is changed from the trans-conformation to the cis-conformation after UV irradiation. The surface tension of AS was measured in the aqueous solution and the corresponding physicochemical parameters were calculated. The results show that after UV irradiation the values of cmc and γ cmc increase, Г max decreases, and A min increases. The contact angle of the AS solution was measured on the quartz surface. The results show that the contact angle decreases after UV irradiation, and the wetting properties of AS is increased on the quartz surface. The adsorption process of AS was studied on the quartz surface by QCM-D. The results show that the amphiphilic molecule can adsorb onto the quartz surface to form a rigid film. After UV irradiation, the adsorption mass of AS is decreased on the quartz surface and the thickness of the adsorption film is decreased.
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    Synthesis and Application of PEDOT: PSVMA/AuNPs Conductive Inks
    ZHANG Yulin, PENG Bo, YUAN Yan, LIU Ren, LIU Jingcheng, LI Zhiquan, LIU Xiaoya
    Imaging Science and Photochemistry    2016, 34 (5): 452-464.   DOI: 10.7517/j.issn.1674-0475.2016.05.452
    Abstract711)      PDF (6776KB)(1934)       Save

    In this paper, styrene sulfonate (SS), 7-(4-vinylbenzyloxyl)-4-methylcoumarin (VM) and acrylic acid(AA)were polymerized by free radical copolymerization to form the photosensitive amphiphilic alternating copolymer P(SS-co-VM-co-AA) (PSVMA). The structure of PSVMA were confirmed by 1HNMR and UV-Vis spectroscopy. PSVMA was used as the soft template to achieve the oxidative polymerization of poly(3, 4-ethylenedioxythiophene) (PEDOT) meanwhile acted as the dopant of PEDOT. Gold precursor chloroauric acid was used as the oxidant for the oxidative polymerization and caused the situ reduction of gold nanoparticles at the same time. The stable PEDOT:PSVMA/AuNPs photosensitive aqueous dispersion was obtained, and mean diameter was 66.7±0.5 nm. PEDOT:PSVMA/AuNPs aqueous dispersion was used as the base ink to achieve the conductive inkjet printing ink with suitable surface tension and viscosity, obtaining flexible conductive film on photopaper and PET substrates by inkjet printing. Those devices showed good conductivity. At the same time, PEDOT:PSVMA/AuNPs could be cross-linked after photo-dimerization of coumarin group, which can improve the devices' water resistance.

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    THE MECHANISM AND APPLICATION OF HYBRID UV CURING SYSTEM
    CHEN Ming, CHEN Qi-dao, XIAO Shan-qiang, HONG Xiao-yin
    Imaging Science and Photochemistry    2001, 19 (3): 208-216.   DOI: 10.7517/j.issn.1674-0475.2001.03.208
    Abstract1588)      PDF (361KB)(5370)       Save
    Hybrid UV curing or dual curing consists of two or more kinds of polymerization or crosslinking reactions that take place in the same system, which is a novel approach to modify polymer materials in-situ. Hybrid UV curing system includes free radical-cationic hybrid UV curing system, Free radical-condensation polymerization system and free radical-free radical system. The mechanism and application of hybrid UV curing are reviewed in this paper.
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    Synthesis of Mercapto-based MTQ Resin and Its Effect on Photocuring Properties of Acrylate System
    LIU Tongzheng, WANG Yong, XUE Tanlong, WANG Tao
    Imaging Science and Photochemistry    2019, 37 (5): 456-464.   DOI: 10.7517/issn.1674-0475.190520
    Abstract421)      PDF (3533KB)(804)       Save
    The mercapto-based MTQ resin(SH-MTQ) was synthesized by hydrolysis copolymerization of hexamethyldisiloxane, γ-(methacryloyloxy)propyltrimethoxysilane and tetraethyl orthosilicate under acidic conditions. The obtained resin was analyzed by Fourier transform infrared spectroscopy, nuclear magnetic resonance spectroscopy ( 1HNMR), gel permeation chromatography and thermogravimetry. The effect of mercapto-based MTQ resin on the photocuring of TPGDA was investigated by using 1-hydroxycyclohexyl phenyl ketone (184) as a photoinitiator. It was found that the addition of mercapto-based MTQ resin increased the photocuring rate and double bond conversion rate of TPGDA, and the properties of cured film hardness, thermal stability, transmittance and contact angle also increased.
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    Research Progress of Chemically Amplified Photoresist Materials
    ZHENG Xiangfei, SUN Xiaoxia, LIU Jingcheng, MU Qidao, LIU Ren, LIU Xiaoya
    Imaging Science and Photochemistry    2020, 38 (3): 392-408.   DOI: 10.7517/issn.1674-0475.191011
    Abstract738)      PDF (1630KB)(1320)       Save
    The drive toward higher integration degree of chips has led to the development of new resist materials with high resolution. The lithography technology is also developed from ultraviolet full-spectrum to single short-wavelength based on the radiation source. In order to meet the requirements of high sensitivity and resolution of photoresist, chemically amplified photoresists have been developed. "Chemical amplified" can increase the quantum yields and enhance the sensitivity of photoresist, which has been widely used in deep ultraviolet and extreme ultraviolet photoresists. As the film forming agent of photoresist, the resin has a significant effect on the performance of photoresist. This paper focuses on several types of reactions in chemically amplified photoresists:deprotection, rearrangement, intramolecular dehydration, esterification polycondensation, crosslinking and depolymerization reaction. In addition, a series of polymers based on chemically amplified are highlighted, since different resin structures correspond to different reaction mechanisms.
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    Analysis of the Effect of IVIM Quantitative Analysis on Differential Diagnosis of Different Molecular Types of Breast Cancer
    WANG Lin, CHEN Xiangrong, XU Shuhui, LIAN Tao, LIN Qiansen, YU Meiying
    Imaging Science and Photochemistry    2020, 38 (2): 368-375.   DOI: 10.7517/issn.1674-0475.191018
    Abstract343)      PDF (1281KB)(604)       Save
    To evaluate the application value of IVIM-DWI in differentiating different molecular subtypes of breast cancer. The clinical data of 121 patients with breast cancer who were hospitalized in our hospital from July 2016 to March 2019,and 32 patients with benign breast masses were retrospectively analyzed. All patients underwent MRI assessment and IVIM-DWI imaging. The ADC value and the IVIM-DWI multi-parameter values were obtained.The quantitative detection of ADC and IVIM-DWI multiple parameter values among different molecular subtypes of breast cancer was compared. (1) The ROC curve shows that in the identification of benign and malignant breast lumps, The area under the curve of D value is larger than ADC, D * and f ( P<0.05); The area under the curve predicted by the four indexes was significantly higher than that predicted by the four indexes alone ( P<0.05).(2) The D value in the tumor tissues of the ER and PR negative groups was lower than that of the positive group, and the D * value was higher than that of the positive group ( P<0.05). The ADC value and D value in the tumor tissues of Ki67<14% group were higher than those in Ki67 ≥ 14% group, and the D * value was lower than that in Ki67 ≥ 14% group ( P<0.05); In the HER-2 positive group tumor, the f value in the tissue was higher than that in the HER-2 negative group ( P<0.05); (3) There were differences in ADC value, D value, D * value and f value between different types of breast cancer, among which the three negative breast cancer group showed lower ADC value, D value and higher f value ( P<0.05). IVIM is a valuable magnetic resonance technique that can be used to identify benign and malignant breast masses and to differentiate breast cancer molecular subtypes. Understanding the characteristics of breast cancer through IVIM parameters provides a new way to accurately assess breast cancer.
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    Dendrimer-Based Nanoscale CT Contrast Agents: Preparation and Biomedical Applications
    PENG Chen, SHI Xiang-yang
    Imaging Science and Photochemistry    2013, 31 (2): 81-90.   DOI: 10.7517/j.issn.1674-0475.2013.02.001
    Abstract1476)      PDF (1541KB)(2042)       Save
    Dendrimers are a family of highly branched, monodispersed synthetic macromolecules with well defined structural composition and architecture. Based on the unique structure of dendrimers, the synthesis and application of novel types of dendrimer-related CT imaging agents are reviewed in this article. Furthermore, future perspectives in the application and development of dendrimers-based CT imaging contrast agents are introduced.
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    Synthesis and Photopolymerization of Benzophenone Macromolecular Photoinitiators
    HAO Yajuan, LI Jingfang, LI Dongbing, YANG Jinliang, NIE Jun
    Imaging Science and Photochemistry    2019, 37 (5): 445-455.   DOI: 10.7517/issn.1674-0475.190710
    Abstract379)      PDF (6173KB)(994)       Save
    Two macromolecular photoinitiators PPI 1 and PPI 2 were synthesized and characterized. The results showed that the UV absorption behavior of PPI 1 and PPI 2 are similar to that of 4-BP, the molar extinction coefficient are higher,the rate of photodegradation are faster. Without the addition of EDAB,compared to PPI 1 and PPI 2, as the molecular weight (functionality) of photoinitiator increased, the polymerization rate increased and the final double bond conversion rate of HDDA increased. The extraction amount of film cured by PPI 1 was 44.5% than that of 4-BP,PPI 2 was 40% than that of 4-BP respectively,after immersed in CH 2Cl 2 solution for 5 days.
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    Research Progress of Photonic Sintering Technology in Printable Electronics
    GU Weibing, LIN Jian, CHEN Zheng, CUI Zheng
    Imaging Science and Photochemistry    2014, 32 (4): 303-313.   DOI: 10.7517/j.issn.1674-0475.2014.04.303
    Abstract1096)      PDF (6280KB)(3628)       Save

    Photonic sintering is a kind of low-temperature, selective and non-contact sintering technology, which can sinter nano material ink on the transparent film substrate, realize the function of ink material, and finally obtain the physical properties of printed electronic devices. Photonic sintering technology includeslaser sintering, infrared sintering and pulsed light sintering. They also have their application features, which have been widely concerned in the field of printed electronics. This paper briefly introduces some research progress and application of photonic sintering technology, mainly focusing on the metallic nano conductive inks.

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    The Molecular Imaging Techniques in Medical Imaging
    WU Rui, LIU Cunfang, GE Hongguang, ZHANG Qiang, SONG Juan, SHI Juan, TIAN Guanghui
    Imaging Science and Photochemistry    2018, 36 (4): 359-366.   DOI: 10.7517/j.issn.1674-0475.180102
    Abstract487)      PDF (1216KB)(1035)       Save
    Molecular imaging is an emerging technology in biomedicine recently. Through the visual representation,characterization and quantificacation of biological processes at the cellular and molecular levels within intact living organisms. Molecularing imaging provides effective methods to deeply unravel the mechanism of physiological and pathological processes, detect and monitor diseases and their treatments in real-time. dynamic, subtle, non-invasive, targeting way. Promisingly, it can be predicted that the rapid development of molecular imaging can lead to great changes of clinical medicine in the near future. In this review, molecular imaging was discussed.
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    Research on All-optical Switch Based on Nonlinear Effect of Photonic Crystal
    GUO Yan, ZHU Jianfeng, ZHANG Han, FENG Yunpeng, CHENG Haobo
    Imaging Science and Photochemistry    2020, 38 (1): 15-21.   DOI: 10.7517/issn.1674-0475.190713
    Abstract490)      PDF (4352KB)(923)       Save
    The advantages of all-opticalization with its fast transmission processing have become the current research hotspot. Among them, all-optical switches play an important role in all-optolight. In this paper, the energy band of photonic crystal structure is calculated by plane wave expansion method and super-cell technology, and the forbidden band characteristics are analyzed. Through the analysis of the energy band characteristics of several photonic crystals, the design research of all-optical switch based on tetragonal crystal structures is determined. Based on the tetragonal system structure, the 15 all-optical switch structure with waveguide and cavity coupling is designed. The time domain finite difference method is used to simulate the electromagnetic field distribution map. On the basis of this, the structure was optimized and the performance of the switch was slightly improved. By studying the forbidden band characteristics of photonic crystals and analyzing the simulation results of all-optical switches, it can be determined that the nonlinear Kerr effect based on photonic crystals can design an all-optical switch structure with excellent switching performance and reduce the size and reaction time of all-optical switch.
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    Diagnostic Value of CT Combined with Serum Tumor Markers in Cervical Cancer Patients with Retroperitoneal Lymph Node Metastasis
    HAN Qianqian, BU Dao
    Imaging Science and Photochemistry    2020, 38 (6): 982-987.   DOI: 10.7517/issn.1674-0475.200517
    Abstract372)      PDF (1248KB)(404)       Save
    122 cases of cervical cancer patients were selected as the research object. According to the results of pathological examination, they were divided into metastasis group (28 patients with retroperitoneal lymph node metastasis) and non-metastasis group (94 patients without retroperitoneal lymph node metastasis). All of them were subjected to CT examination of the whole abdomen and detection of serum tumor markers including carcinoembryonic antigen (CEA), cancer antigen 125 (CA125) and squamous cell carcinoma antigen (SCC-Ag). The results showed that the shortest diameter of CT lymph nodes in the metastatic group was longer than that in the non-metastatic group, and the levels of serum CEA, CA125 and SCC-Ag were higher than those in the non-metastatic group ( P<0.05). Serum CEA, CA125, SCC-Ag levels were positively correlated with the shortest diameter of the lymph nodes in the horizontal axis of CT, and the sequence of AUC value for diagnosis of retroperitoneal lymph node metastasis was:CT combined with serum tumor markers > the shortest diameter of CT lateral axis lymph node > SCC-Ag > CEA > CA125. It can provide an objective basis for clinical preoperative evaluation of the presence of retroperitoneal lymph node metastasis.
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    Study on Nano Metal Oxide Thermal Insulation Film and Properties
    QIN Changxi, NIU Juanni, GAO Chao
    Imaging Science and Photochemistry    2017, 35 (1): 80-87.   DOI: 10.7517/j.issn.1674-0475.2017.01.080
    Abstract671)      PDF (2573KB)(1400)       Save

    This article studies the relationship between particle size and coating thickness of UV cured nano metal oxides(ATO), as well as the insulation properties of the film, the performance and characteristics of nano coating thermal insulation film and magnetron sputtering. Results show that, functional degree of the light cured resin monomer and other components, the amount of nano metal oxides and the size of the nano materials have a close relationship. With a reasonable material combination of the insulation film, insulation rate can reach more than 50%. Compared to the magnetron sputtering films, nano coating insulation film shows highly pervious to light and improved thermal insulation and good thermal insulation performance. Even after damp heat aging, the infrared transmittance change of nano thermal insulation film is only about 5%.

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    The Self-calibration Technology of Camera Intrinsic Parameters Calibration Methods
    ZHANG Jiyou, WANG Dongjie, MA Lina
    Imaging Science and Photochemistry    2016, 34 (1): 15-22.   DOI: 10.7517/j.issn.1674-0475.2016.01.015
    Abstract671)      PDF (2291KB)(3331)       Save

    Camera self-calibration technology is a camera calibration that only use the images of surroundings and the relative relationships of images but not relying on the calibrating reference. Self-calibration only needs to match the points on images. The method is very flexible and has a wide application range. We introduced the basic principles and arithmetic of self-calibration, and introduced the research condition of inland and foreign with the calibration results. At last, we approached the key technologies of self-calibration methods.

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    The Development and Latest Applications of Digital Image Correlation in Stress and Strain Measurement
    ZHANG Shunqing, GAO Chenjia, ZHANG Long
    Imaging Science and Photochemistry    2017, 35 (2): 193-198.   DOI: 10.7517/j.issn.1674-0475.2017.02.193
    Abstract670)      PDF (1055KB)(1714)       Save

    In the area of modern materials stress and strain measurement, DIC(digital image correlation) has the advantages of non-contact, full field, low requirement of experimental conditions and high precision. It is an effective and practical method of stress and strain measurement, which is widely used in experimental mechanics and other fields. In this paper, the development of DIC in materials stress and strain is summaried and DIC is compared with other measurement techniques. Then, the system structure, related algorithms and search methods of DIC are introduced. Finally, the latest applications and new products of DIC in stress and strain of materials are listed.

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    Development and Application of Digital Holographic Microscopy in Biomedicine
    WU Yumin, SONG Guoqing, FENG Yunpeng, WANG Zhong
    Imaging Science and Photochemistry    2016, 34 (1): 23-29.   DOI: 10.7517/j.issn.1674-0475.2016.01.023
    Abstract966)      PDF (1819KB)(2061)       Save

    In recent years, with the rapid development of optoelectronic imaging devices such as CCD and computer technology, digital holographic microscopy technology has been developed, which has been widely used in the field of biomedicine with the characteristics of no-contact, quantitative, three-dimensional imaging.The development of digital holographic microscopy is reviewed.The advantages and disadvantages of digital holographic microscopy and other techniques are compared.From the point of view of light source, the important influence of different light source on digital holographic microscopy imaging and the corresponding algorithm are discussed.The latest applications of digital holographic microscopy in biomedicine are enumerated.

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    Synthesis and Spectrometric Detection of Lindqvist Acid and Aniline Hybrid Solid
    ZHANG Yucai, CHEN Hongman, DENG Renpan, YAN Yin, MIAO Zhiwei
    Imaging Science and Photochemistry    2018, 36 (6): 514-521.   DOI: 10.7517/issn.1674-0475.180802
    Abstract495)      PDF (769KB)(758)       Save
    Using Lindqvist hexamolybdate as an inorganic composite and aniline as an organic composite, a covalently linked hexamolybdopolyacid-aniline hybrid solid was synthesized by dehydration method with dicyclohexyl carbodiimide. The compound was characterized by 1HNMR, 13CNMR, IR and UV-Vis spectroscopy. The UV-Vis spectra of the compound showed that the apparent red-shifted band (about 37 nm) was observed compared with aniline, which confirmed that the triple bond formed between Mo and N, and further increased the conjugation of the system. IR spectra displayed that the compound kept the basic structure of Lindqvist polyacid. UV-Vis spectroscopy was used to detect different concentrations of Vitamin C. It was found that the absorbance of the hybrid solution didn't change significantly after repeated cycles, indicating that the UV-visible probe can be recycled.
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    The Triplet State Conversion to Singlet Excited State in OLED
    WU Shikang
    Imaging Science and Photochemistry    2014, 32 (3): 217-237.   DOI: 10.7517/j.issn.1674-0475.2014.03.217
    Abstract1654)      PDF (3975KB)(2976)       Save

    The interesting in the field of OLED study is how make the most of the application of triplet exciton for enhancing the efficiency of electro-luminescent conversion in device. Recently, the appearance of the thermo-activated delay fluorescence (TADF) which may through inverse upper conversion to obtain the delay fluorescence used in OLED, leads to a wonderful perspective in this field. In this review, several basic problems are discussed in details concluding such as the electron excitation, excited state splitting, exchange energy between singlet and triplet states, the recombination of charge carries, the formation of exciton, and the charge transfer(CT) problems in pure organic and organo-transition metal complex, etc.

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    Evaluation of Coronary Stenosis and Plaque Stability by Multi-slice Spiral CT Angiography in Patients with Coronary Atherosclerotic Heart Disease
    XU Weihua
    Imaging Science and Photochemistry    2020, 38 (3): 491-495.   DOI: 10.7517/issn.1674-0475.191115
    Abstract364)      PDF (590KB)(461)       Save
    To investigate the detection efficiency of multi-slice spiral CT angiography (MSCTA) on coronary stenosis and plaque stability, 80 patients with coronary heart disease in our hospital from July 2018 to August 2019 were selected in this study. All patients were examined by angiography (CAG) and MSCTA. The results of CAG were used as control, the detection efficiency of coronary stenosis and plaques by MSCTA was calculated. The results show that the sensitivity, specificity and coincidence rate of MSCTA in detecting coronary stenosis were in good agreement with CAG (kappa=0.871, P=0.000). There was no significant difference in the detection rate of coronary artery stenosis, mild stenosis, moderate stenosis and severe stenosis between MSCTA and CAG ( P>0.05). The main coronary plaques in patients with stable angina are calcified plaques, and the main coronary plaques in patients with unstable angina are soft plaques. MSCTA has a statistically significant difference in the detection rate of coronary plaque between patients with stable angina and unstable angina ( P<0.05). Therefore, MSCTA has a high diagnostic efficiency for coronary stenosis. It can effectively evaluate the degree of coronary stenosis and plaque stability in patients with coronary heart disease, as well as provide reliable imaging basis for clinical treatment and prognosis evaluation.
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    The Technology of Lensless Digital Holographic Microscopy and Its Application
    SHENG Haijian, WU Yumin, WEN Yongfu, LI Gen, CHENG Haobo
    Imaging Science and Photochemistry    2017, 35 (2): 99-105.   DOI: 10.7517/j.issn.1674-0475.2017.02.099
    Abstract915)      PDF (2536KB)(2581)       Save

    Aiming at the observation of micro structures and micro optical elements, we proposed a fast and nondestructive microscopic observation method based on lensless digital holography technology. Firstly, the basic principle of lensless digital holographic microscopy imaging technology based on spherical wave is introduced. CCD was adapted as photoelectric converter, designed the lensless digital holographic microscopy imaging system based on Michelson interference optical path,and the reflection mirrors were used to form a folded back optical path, which made the system structure simple,compact, and have a better portability. And we used USAF1951 resolution plate performed resolution calibration experiment and got that the resolution of the system was 6.69 μm,amplified factor was 3.375, and working distances was 12 mm. A practical measurement of the surface structure of wafer was also carried out. Experiments verified the feasibility and effectiveness of the system, and the method is expected to be applied to perform quantitative measurement for the surface topography of MEMS, micro optical elements and so on.

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    Preparation and Application of Carbon Quantum Dots Based on Up Conversion Photoluminescence
    DENG Yafeng, ZHOU Yihua, QIAN Jun, LUO Yan, WU Lihui
    Imaging Science and Photochemistry    2017, 35 (6): 884-893.   DOI: 10.7517/j.issn.1674-0475.2017.05.010
    Abstract796)      PDF (1666KB)(1966)       Save

    CQDs have the characteristics of easy preparation, low toxicity, high chemical inertia, stable fluorescence properties and so on. CQDs and other carbon nanomaterials (such as fullerene, carbon nanotubes and graphene) have attracted the attention of researchers. The synthesis, properties, modification and application of CQDs are discussed in this paper, especially on the Up Conversion Photoluminescence that long wavelength excitation can emit short wavelength. Some implications for the synthesis, modification and application of CQDs based on up conversion photoluminescence are discussed in this paper too.

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    Homogeneous Photocatalytic Reduction of CO 2 under Visible Light Irradiation: Recent Developments and Future Challenges
    CHEN Jinping, DU Xinfeng, YU Tianjun, ZENG Yi, ZHANG Xiaohui, LI Yi
    Imaging Science and Photochemistry    2015, 33 (5): 358-373.   DOI: 10.7517/j.issn.1674-0475.2015.05.358
    Abstract917)      PDF (2537KB)(1557)       Save

    The research field of the solar-driven reduction of carbon dioxide to fuels or fine chemicals has grown rapidly in the past few decades. It is still a great challenge to develop efficient photocatalytic systems for CO2 conversion. Photochemical CO2 reduction in homogeneous solution plays an important role in the mechanism investigation, catalyst development and parameter optimization. This review will present much of the significant work that has been done in the field of homogeneous photocatalytic reduction of CO2 over the recent five years. The challenges and prospects for further development of homogeneous system are presented.

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    DISSOLUTION INHIBITION MECHANISMS OF POSITIVE PHOTORESIST BASED ON NOVOLAK-DNQ
    GAO Ying-xin, BAO Yong-zhong, HUANG Zhi-ming, WENG Zhi-xue
    Imaging Science and Photochemistry    2004, 22 (1): 33-43.   DOI: 10.7517/j.issn.1674-0475.2004.01.33
    Abstract1723)      PDF (450KB)(3592)       Save
    The mechanisms of dissolution inhibition of positive photoresist based on novolak(NVK)-diazonaphthoquinone(DNQ),including(1) the molecular hydrogen bonding interactions between novolak and DNQ;(2) mechanism of the azoxy- or azo-coupling reaction of DNQ-ester with novolak resin;(3) the two-step mechanism (also named static and dynamic inhibition) of dissolution inhibition;(4) mechanism of the surface of the photoresist;(5) the molecular dissolution of novolak related to the mechanism of inhibition,was reviewed in this paper.
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    Novel Colorimetric Method for Urine Test Strips Based on Smartphone Image
    YANG Renbing, CHENG Wenbo, QIAN Qing, ZHANG Qiang, BAI Pengli, PAN Yujun, DUAN Peng
    Imaging Science and Photochemistry    2018, 36 (4): 340-349.   DOI: 10.7517/j.issn.1674-0475.180109
    Abstract719)      PDF (5054KB)(813)       Save
    This paper proposes a new colorimetric analysis algorithm based on smartphone images. Conforming to human eye vision, it has the advantages of minor calculation and best calculating stability. This method converts the color information of the original nonlinear RGB color space to the CIELab color space that conforms to the human vision, therefore the reference color closest to the test color can be accurately picked. Meantime, "vertical point method" is proposed innovatively to further quantify the similarity of color information and realize the quantitative analysis of urine test strips. As for the experiment, the pH (4.59.5), glucose content (060 mmol/L) and protein content (04 g/L) in artificial urine were quantitatively analyzed by taking photos of urine test strips in an ambient light-isolated box, and visual colorimetry was used as a control. The results show that the proposed colorimetric algorithm is not only accurate, reliable, reproducible and computable, but also suitable for application in urine test strip colorimetric analysis based on mobile phone images.
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    Recent Advances of the Near-infrared Fluorescent BODIPY/aza-BODIPY Dyes
    YUE Shuai, SHAO Zhumei, JIANG Xindong
    Imaging Science and Photochemistry    2020, 38 (4): 585-600.   DOI: 10.7517/issn.1674-0475.191216
    Abstract840)      PDF (3173KB)(973)       Save
    This review covers the design, synthesis and functionalization of BODIPY/aza-BODIPY as fluorophore probes since 2002, including applications for fluorescence quenching, metal ion, anion, biomolecular detection, etc. Synthesis, properties and application of novel aza-BODIPY, substituted aza-BODIPY on the boron center, new near-Infrared-fluorescent aza-BODIPY dyes with 1-methyl-1H-pyrrolyl substituents at the 3, 5-positions and so forth, were herein discussed.
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    Imaging Characteristics and Related Factors of Patients with Cerebral Infarction after Cardiac Surgery
    BAHTIYAR·keram, LI Jian, ZHANG Daquan
    Imaging Science and Photochemistry    2020, 38 (2): 362-367.   DOI: 10.7517/issn.1674-0475.191006
    Abstract358)      PDF (599KB)(484)       Save
    The imaging features of cerebral infarction patients after cardiac surgery and related factors of cerebral infarction were discussed. 286 cases of cardiac surgery patients were selected as the study subjects. 34 cases of cerebral infarction occurred after operation. According to different surgical methods, the patients with cerebral infarction were divided into 11 cases of cardiopulmonary bypass group and 23 cases of non-extracorporeal circulation group. The imaging features of postoperative cerebral infarction were compared between the two groups, and the influencing factors of cerebral infarction after cardiac surgery were analyzed. The results showed that there was no significant difference in the incidence of perforation, watershed infarction, multiple infarction, and old infarction between the two groups ( P>0.05). The incidence of cortical infarction in the extracorporeal circulation group was significantly lower than that in the non-extracorporeal circulation group. The incidence of large infarction and bilateral infarction in the extracorporeal circulation group was significantly higher than that in the non-extracorporeal circulation group, and the difference was statistically significant ( P<0.05). Univariate analysis showed that gender, fasting blood glucose, TC, TG, LDL-C, Hcy, smoking, and drinking were not the influencing factors of cerebral infarction after cardiac surgery ( P>0.05); age, education level, history of hypertension, diabetes as heart Influencing factors of cerebral infarction after surgery ( P<0.05); multivariate binary logistic regression analysis, high age, low education, history of hypertension ≥ 10, diabetes was an independent influencing factor of cerebral infarction after cardiac surgery ( P< 0.05). This article shows that extracorporeal circulation surgery is often a large area of infarction, bilateral infarction, heavier symptoms, non-extracorporeal circulation surgery is often cortical infarction, and both watershed infarction, more related to embolism and hypoperfusion. Cerebral infarction after cardiac surgery is closely related to high age, low level of education, history of hypertension ≥ 10, and diabetes. Early targeted prevention intervention may reduce the incidence of cerebral infarction.
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    Development of Matrix Resins for 248 nm Deep UV Photoresist
    WEI Zibo, MA Wenchao, QIU Yingxin
    Imaging Science and Photochemistry    2020, 38 (3): 430-435.   DOI: 10.7517/issn.1674-0475.191014
    Abstract598)      PDF (1046KB)(848)       Save
    Different kinds of matrix resins and structures used in 248 nm chemically amplified deep UV photoresist were summarized,including poly(methyl methacrylate) and its derivatives, poly(p-hydroxystyrene) and its derivatives, N-substituted maleimide derivatives and other polymers, and the influences of the structure and exposure conditions of film-forming resins or monomers on photoresist properties were discussed.
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