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Table of Content

    15 March 2020, Volume 38 Issue 2
    Content
    2020, 38(2):  0-0. 
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    Review and Articles
    The Construction of Double Ligands Zn(Ⅱ)MOFs and Its Photoluminescence Properties
    ZHU Wenqing, FAN Pan, LI Yang, ZHU Yumeng, ZHANG Jin
    2020, 38(2):  159-166.  DOI: 10.7517/issn.1674-0475.190811
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    2,5-dihydroxyterephthalic acid (H4-DHBDC) and 4,4'-bipyridine (4,4'-Dipyridyl) as double ligands, Zn(NO3)2·6H2O as a metal salt, the solvothermal method was adopted in a solvent system of water/DMF=3:2 (volume fraction) and a Zn(Ⅱ)MOFs material was constructed by solvothermal method at 120℃. Its composition was[Zn2(H2-DHBDC)(DHBDC)0.5(4,4'-Dipyridyl)1.5]n. The crystal structure and properties were analyzed and characterized by X-ray single crystal diffraction(PXRD), infrared spectroscopy(FTIR), thermogravimetric analysis(TGA) and fluorescence spectrophotometry(FS). The results showed that the Zn(Ⅱ)MOFs material belongs to the monoclinic system, P2(1)/n space group, and has a three-dimensional network structure. The analysis of thermogravimetric and fluorescence show that the Zn(Ⅱ)MOFs material has good thermodynamic stability and photoluminescence property.
    The Applications of UV-LED
    JIN Yangzhi
    2020, 38(2):  167-174.  DOI: 10.7517/issn.1674-0475.190823
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    The charactristics, the application and the development of UV-LED are described in details.
    The Design and the Accuracy Correction of the Illumination Detector
    ZHENG Danyang, FENG Yunpeng, WANG Zhongying, LI Hui, CHENG Haobo
    2020, 38(2):  175-180.  DOI: 10.7517/issn.1674-0475.190912
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    The airfield lighting system provides safety for the take-off/landing safe of aircraft at night or in low visibility environments. It is an important task to measure and judge quickly and accurately whether the light intensity level, light illumination angle, etc. meet the standards of the International Civil Aviation Organization (ICAO) to ensure the safe operation of the airport. In this paper, the illuminance detector based on the silicon photocell is designed. The visibility curve V(λ) is completed by the combination of cosine corrector and different filters, realizing the high-speed dynamic detection technology accurately. The linear calibration and dynamic accuracy measurement of the illuminance detection is completed by experiments. The illuminance measurement error rate and the dynamic measurement error meet the requirements of ICAO regulations. The high-speed dynamic detection of light intensity in parallel sections of navigation aids is realized.
    Research on Multi-diffraction Phase Imaging Restricted by Large Numerical Aperture Optical Lens
    WANG Qian, CHEN Xin, WEN Yongfu, YANG Hao, WANG Huaying, CHENG Haobo
    2020, 38(2):  181-189.  DOI: 10.7517/issn.1674-0475.191001
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    Digital holographic microscopy imaging technology is a quantitative phase imaging technology combined with digital holography technology and traditional optical microscopy imaging technology. Owing to there are speckles and parasitic stripe noise in traditional laser off-axis holographic microscopy imaging system and the traditional off-axis digital holographic microscopy of partial coherent light illumination has the problem of poor contrast of coherent fringes, the diffraction phase microscopy imaging system with monochromatic LED illumination is putted forward in this paper. Grating is used to obtain multi-level diffraction of object light. And 0th and +1st order light are separated by 4f system and spatial filter, which are used as reference light and signal light, respectively. Two beams interfere with each other on the CCD and generate off-axis hologram. Thereby a common-path and off-axis holographic imaging structure is formed. Through theoretical analysis and calculation, the optical components used in the experiment are picked to guarantee that the diffracted light spectrum information can be separated and accord with the sampling conditions. In conclusion, the experimental results demonstrate that the proposed system can derive higher imaging accuracy and signal-to-noise ratio than the traditional laser off-axis digital holographic microscopy imaging results.
    Cationic Photopolymerization Kinetics of a Cycloaliphatic Diepoxide Using a Ferrocenium System Under UV-LED Exposure
    GAO Yang, SU Jiahui, LIU Xiaoxuan
    2020, 38(2):  190-199.  DOI: 10.7517/issn.1674-0475.190922
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    Cationic photopolymerization kinetics of cycloaliphatic diepoxide (CE) has been investigated by real-time Fourier transform infrared spectroscopy (real time FTIR) under UV-LED light (405 nm),using cyclopentadien-Fe-cymene hexafluorophosphate (I-261) as an initiator and using 2-isopropyl-9H-thioxanthen-9-one (ITX), curcumin (CC), and 1-[4-(phenylazo)phenyl]azo]-2-naphthaleno (Sudan Ⅲ) as the photosensitizers. The enhancing monomer conversion rate and polymerization rate of CE was achieved by complex initiator with photosensitizers. All photosensitizers were effective in initiating the photopolymerization while ITX and CC exhibited higher efficiency during the photopolymerization. As a result, with 8.0%(mass fraction) I-261 and 0.5% ITX, the monomer conversion of CE has reached to more than 89% from 74.4%,the maximum polymerization rate increased to 1.9 times. Moreover, using 8.0% (mass fraction) I-261 and 1.0% CC, the monomer conversion of CE has reached to more than 88% from 74.4%,the maximum polymerization rate increased to 1.7 times for the epoxy system.
    Application Value of Multi-slice Spiral CT Three-dimensional Reconstruction in the Diagnosis of Spinal Fracture
    CHENG Yanping, ZHAO Hu
    2020, 38(2):  200-205.  DOI: 10.7517/issn.1674-0475.190813
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    The application value of multi-slice computed tomography (CT) three-dimensional reconstruction in the diagnosis of spinal fractures is analyzed in this study. 70 patients with spinal fractures who sought medical care in our hospital from January 2017 to October 2018 were enrolled. X-ray examination and multi-slice spiral CT three-dimensional reconstruction were performed with informed consent. The results of the operation were the diagnostic criteria, and the difference between the two diagnostic methods were compared. The diagnostic coincidence rates of X-ray on the fracture site, the fracture type, and the spinal canal stenosis were lower than those of the multi-slice spiral CT. The difference was statistically significant (P<0.05). The sensitivity, specificity and accuracy of the three-dimensional reconstruction of multi-slice spiral CT was higher than that of X-ray examination, and the difference was statistically significant (P<0.05). According to this, in the clinical diagnosis of spinal fractures, multi-slice spiral CT three-dimensional reconstruction can accurately reveal the fracture site and fracture type, and the sensitivity, specificity and accuracy are at a high level, which is worthy of popularization in future clinical work.
    The Ultrasonographic Features of Hyperplasia of Mammary Glands in Different Menstrual Cycles
    ZHOU Xiwei
    2020, 38(2):  206-210.  DOI: 10.7517/issn.1674-0475.190815
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    In ordr to discuss the ultrasonographic features of hyperplasia of mammary glands in different menstrual cycles, 102 patients with hyperplasia of mammary glands was analyzed in this study. From June 2017 to June 2019, they were selected as the subjects and examined by color Doppler ultrasound in different menstrual cycles (menstrual, proliferative and secretory stages). The sex hormones[estradiol (E2), progesterone (P)] were detected, and the ultrasonographic features of hyperplasia of mammary glands in different menstrual cycles were analyzed. The results showed that, among 102 cases of hyperplasia of mammary glands, 98 cases were diagnosed by color Doppler ultrasound, and the coincidence rate was 96.08%. Compared with pathological results, there was no significant difference (P>0.05). The thickness of breast body layer, duct width, breast pain rate and E2 level in proliferative period of patients with hyperplasia of mammary glands were significantly higher than those in menstrual period and secretory period. The level of P in proliferative period was significantly lower than that in secretory period, but significantly higher than that in menstrual period. The thickness of breast body layer, duct width, breast pain rate and E2 level in secretory period were higher than those in menstrual period, but there was no significant difference (P>0.05). This study confirms that, color Doppler ultrasonography has good diagnostic value for hyperplasia of mammary glands, and there are differences in ultrasonographic features of hyperplasia of mammary glands in different menstrual cycles. It can effectively evaluate the relationship between menstrual cycle, sex hormones and proliferative lesions.
    Value of CT Perfusion Combined with Blood-brain Barrier Marker Protein in Evaluating Neuronal Damage in Patients with Toxic Shock
    LIANG Ruijin, XIAN Xuefang, DING Ling, ZHOU Lingling
    2020, 38(2):  211-217.  DOI: 10.7517/issn.1674-0475.190817
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    The clinical data of 100 patients with clinically confirmed toxic shock admitted to our hospital from December 2017 to November 2018 were selected. All the patients underwent CT perfusion imaging.The original images were processed by the perfusion software in the workstation to produce pseudo-color images of perfusion parameters. Cerebral blood flow (CBF), cerebral blood volume (CBV), mean transit time (MTT), peak time (TTP) of the lesion side and the contralateral cerebral hemisphere was measured, and other perfusion parameters(rCBF, rCBV, rMTT, rTTP) were used to calculate the relative ratio of lesion side to opposite side. The expression of claudin-5, occludin, ZO-1, JAM-1, NOS and NSE in different patients were detected by immunohistochemical method, and the correlation between the protein levels and the perfusion paraneters was compared. The results showed that rCBF in peripheral blood and cerebrospinal fluid decreased significantly, rTTP decreased and rPS increased significantly in the observation group (P<0.05), but there was no significant difference in rMTT and rCBV between the two groups (P>0.05). The claudin-5, occludin, ZO-1 and NOS in peripheral blood and cerebrospinal fluid of the patients in the observation group decreased significantly, while JAM-1 and NSE increased significantly (P<0.05). In the observation group, claudin-5, occludin, ZO-1 and NOS were positively correlated with rCBF and rTTP, negatively correlated with rPS; JAM-1 and NSE were negatively correlated with rCBF and rTTP, and positively correlated with rPS. rCBF, rTTP, JAM-1 and NSE were positively correlated with neuronal injury, while claudin-5, occludin, ZO-1 and NOS were negatively correlated with neuronal injury. It is suggested that CT blood perfusion combined with blood brain barrier marker protein can effectively evaluate neuronal damage in patients with toxic shock, and it is worth popularizing and applying.
    Diagnostic Value of 18F-FDG PET/CT Imaging Combined with Tumor Markers in Unexplained Peritoneal Effusion in Women
    XIE Ran, YANG Qingxiong
    2020, 38(2):  218-224.  DOI: 10.7517/issn.1674-0475.190819
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    The aim of this paper is to investigate the value of 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) combined with tumor markers in diagnosis of unexplained peritoneal effusion in women. The 18F-FDG PET/CT imaging data and tumor markers of 95 women with unexplained peritoneal effusion were retrospectively analyzed and compared with the pathological diagnosis. In the 95 patients, 74 patients were malignant and 21 patients were benign. The diagnostic sensitivity, specificity and accuracy of PET/CT for benign and malignant ascites were 98.65%, 19.05% and 81.05%, respectively. The SUVmax of malignant peritoneal effusion was significantly higher than that of benign peritoneal effusion (P>0.05). The patients were further subdivided according to the etiology, SUVmax in ovarian cancer group was significantly higher than that in group of other benign causes (P<0.05), but there was no significant difference between the ovarian cancer group, the tuberculosis group and other malignant tumors group (P>0.05). CA125 was the most effective marker for the diagnosis of ovarian cancer and tuberculosis-induced peritoneal effusion. The sensitivity, specificity and accuracy of CA125 were 98.2%, 7.7% and 81.4%, respectively. There was no significant difference between the diagnosis of CA125 or PET/CT alone and the combined diagnosis of them (P>0.05). The research shows that 18F-FDG PET/CT has high sensitivity and accuracy in the diagnosis of unexplained peritoneal effusion in women, but its specificity is poor. Combined examination of tumor markers can not improve the diagnosis of ascites caused by ovarian cancer and tuberculosis.
    Study on the Relationship between the Characteristics of TE Imaging, Severity and Insulin Resistance in Patients with NAFLD
    DAI Shuquan, YU Maowen, LI Jun, LIAO Changli, TANG Yan, LIU Qianguo, ZHANG Yaping
    2020, 38(2):  225-230.  DOI: 10.7517/issn.1674-0475.190820
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    The purpose of this study is to analyze the relationship between the imaging characteristics of TE(transient elastography) in patients with NAFLD(non-alcoholic fatty liver disease) and their severity and insulin resistance. We chose 112 patients with NAFLD and 108 patients with health check-up, compared the baseline data of the two groups of patients, and grouped the patients with NAFLD according to the condition and compared the relevant data.Research shows that the liver function, serum insulin, HOMA-IR(insulin resistance index) were significantly higher in the NAFLD group than in the control group (P< 0.05). With the increase of fatty liver severity, the general age of patients increased, more men than women, liver hardness, liver function, and insulin-related indicators all increased significantly, with significant differences (P<0.05). The ROC curve analysis showed that CAP(controlled attenuation parameter) had high diagnostic value for mild, moderate and severe NAFLD, with sensitivity of 0.865, 0.861, 0.931, and specificity of 0.614, 0.819, and 0.822, respectively. With the aggravation of severity's condition in NAFLD, the CAP and HOMA-IR values increased significantly and were positively correlated(r=0.536, r=0.479).The TE imaging of NAFLD patients is closely related to the severity of NAFLD. Insulin resistance can also be clinically assisted in the diagnosis of NAFLD.
    Correlation between Ultrasound IMT and Plaque Indicators and Major Risk Factors for Cardiovascular Disease
    LIANG Zhicheng, ZHAO Qiang, LI Mengxue
    2020, 38(2):  231-235.  DOI: 10.7517/issn.1674-0475.190824
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    This article discusses the correlation between carotid intima media thickness (IMT) and plaque indicators and major risk factors for cardiovascular disease. 160 elderly people who were routinely examined in our hospital from January 2014 to December 2018 were selected as subjects. According to different IMT, they were divided into 78 cases in the control group, 52 in the thickening group and 30 in the plaque group. Correlation analysis between carotid IMT and plaque indicators and major risk factors for cardiovascular disease. The results showed that the proportion of men, age, systolic blood pressure, triglycerides, and postprandial 2 h blood glucose level in the thickening group and the plaque group were significantly higher than those in the control group (P<0.05). Multivariate Loglsitlc analysis showed a significant positive correlation between IMT and male ratio, age, systolic blood pressure, triglyceride, and postprandial 2 h blood glucose levels (P<0.05). This article confirms that carotid IMT levels and plaque calcification are significantly associated with male risk factors for cardiovascular disease, male ratio, age, systolic blood pressure, triglycerides, and postprandial 2 h blood glucose level.Clinically, cardiovascular events can be predicted.
    Blood Flow Parameters of Fetal Umbilical Artery, Middle Cerebral Artery and Isthmus of Aortic Arch Measured by Color Doppler Ultrasound in Diagnosis of Fetal Growth Restriction in Late Pregnancy
    WANG Zhuo, REN Xiue, ZHENG Lixia
    2020, 38(2):  236-241.  DOI: 10.7517/issn.1674-0475.190901
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    To analyze the changes of color Doppler flow imaging parameters of umbilical artery, middle cerebral artery and isthmus of aortic arch in fetal growth restriction (FGR) in late pregnancy, and its diagnostic value for FGR, 51 late pregnant women diagnosed as FGR in our hospital from May 2018 to March 2019 were selected as observation group, and 47 late pregnant women with normal pregnancy in the same period were selected as control group. The gestational weeks of the two groups were 34~36 weeks. The blood flow parameters such as pulsation index (PI), resistance index (RI), peak systolic velocity(PSV), end systolic reflux velocity(ESRV), end diastolic velocity(EDV), PSV/EDV(S/D) of umbilical artery, middle cerebral artery and isthmus of aortic arch were measured by GE voluson E8 color Doppler ultrasound, and the data were compared between the two groups. The results showed that, the levels of PI, RI, S/D in umbilical artery and ESRV in isthmus of aortic arch in the observation group were higher than those in the control group, the levels of PI, RI in middle cerebral artery and PSV/ESRV in isthmus of aortic arch were lower than those in control group, the difference was statistically significant (P<0.05). There was no significant difference in PSV levels between the two groups (P>0.05). In a word, blood flow parameters of umbilical artery, middle cerebral artery and isthmus of aortic arch of FGR fetus in late pregnancy changed to some extent. Among them, PI, RI, S/D of umbilical artery and middle cerebral artery, ESRV and PSV/ESRV of isthmus of aortic arch can be used as sensitive indicators for FGR diagnosis.
    The Influence of Multi-slice CT and DSA on Patency and Stenosis Degree of Coronary Artery Stent Implantation in Patients with Acute Coronary Syndrome
    GAO Wenxia, CHENG Min, QIU Dongxia
    2020, 38(2):  242-247.  DOI: 10.7517/issn.1674-0475.190902
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    Abject To study the effects of multi-slice CT and DSA on patency and stenosis degree of patients with acute coronary syndrome after coronary artery stent implantation. Eighty patients with acute coronary syndrome diagnosed and treated in our hospital from August 2017 to November 2018 were selected as the study subjects. After percutaneous coronary intervention (PCI) operation, DSA and 64-slice spiral CT were performed in all patients. The differences of coronary stenosis and patency between different examinations and the consistency of different examinations were analyzed. Through paired chi-square test of CT results and DSA results, there was no significant difference between the two groups. The two methods had good consistency in diagnosis of coronary artery stenosis. There was no difference in diagnosis of wall thickness and diameter between the two methods. In statistical significance, the two methods have good consistency in the diagnosis of wall thickness and diameter of patients. In conclusion, multi-slice CT and DSA have a high consistency in the diagnosis of patency and stenosis degree after coronary artery stent implantation in patients with acute coronary syndrome. It is suggested that they be popularized in clinic.
    Application Value in Diagnosis and Prognosis Evaluation of Echocardiography and Dynamic Electrocardiogram Examination in Patients with Acute Myocardial Infarction
    DING Minxia, TANG Xiangrui, ZHAO Yan
    2020, 38(2):  248-252.  DOI: 10.7517/issn.1674-0475.190903
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    To investigate the application value in diagnosis and prognosis evaluation of echocardiography and dynamic electrocardiogram examination in patients with acute myocardial infarction(AMI), 100 AMI patients admitted and diagnosed in our hospital from June 2016 to June 2018 were selected as the observation group, and 100 patients without coronary heart disease in the same period were selected as the control group. Cardiac death was the end point of AMI, the observation group was divided into death group (n=15) and survival group (n=85). All patients were underwent echocardiography examination by Philips IU-Elite and EPIQ5 color Doppler ultrasound, as well as the dynamic electrocardiogram examination by the standard 12 lead Holter performed with DMS-300 4A electrocardiograph. The changes of heart rate turbulence index[TO, TS], heart rate variability index[SDNN, QTd, QTcd], and cardiac function index[LVEDD, LVEF] levels in each group were compared. The results showed that the TO, QTd, QTcd and LVEDD in the observation group were significantly higher than those in the control group, while TS, SDNN and LVEF were significantly lower than those in the control group (P<0.05). TS and SDNN in death group were significantly lower than those in survival group (P<0.05). The TO of death group was higher than that of survival group, while the QTd, QTcd, LVEF and LVEDD of death group were lower than those of survival group, but there was no significant difference (P>0.05). This study demonstrated that, HRT in patients with AMI decreased or even disappeared, HRV and LVEF decreased, LVEDD and QTd increased, and the QT interval prolonged. The echocardiography combined with dynamic electrocardiogram examination has important clinical value in the diagnosis and prognosis evaluation of patients with AMI.
    Clinical Analysis of IDose4 Iterative Reconstruction in Low Dose CT Renal Artery Angiography
    ZHOU Yongxia, ZHOU Rong
    2020, 38(2):  253-259.  DOI: 10.7517/issn.1674-0475.190904
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    To evaluate the application of IDose4 iterative reconstruction technique in renal artery angiography with low-dose CT,205 patients who were to undergo renal artery CT angiography were randomly divided into four groups. Group A (51 cases) received 100 kV tube voltage, 100 mA tube current, 370 mg I/mL iohexol and IDose4 iterative reconstruction techniques. Group B (51 cases) used 100 kV tube voltage, 150 mA tube current, 270 mg I/mL iohexol and IDose4 iterative reconstruction techniques. Group C (51 cases) used 80 kV tube voltage, 180 mA tube current, 270 mg I/mL iohexol and IDose4 iterative reconstruction techniques.In group D, 52 cases were reconstructed by 120 kV tube voltage, 120 MV tube current, 370 mg I/ml iopromide and filter back projection (FBP). To determine the CT value, noise (SD), signal-to-noise ratio (SNR) and noise ratio (CNR) of renal aorta trunk in each group of images, the subjects received effective CT dose (ED), volumetric CT dose index (CTDIvol), dose length product (DLP), iodine intake, reconstruction image score difference and diagnostic efficacy. The results showed that the scores of reconstructed images in group A, B and C were better than those in group D, CT value of renal artery trunk, SD, SNR and CNR in group A, B and C were higher than those in group D, while CT value of renal artery trunk and SD in group B and C were slightly lower than those in group A. CTDIvol, DLP and ED in group A, B and C were lower than those in group D, while CTDIvol, DLP and ED in group B were higher than those in group A. The diagnostic accuracy of A, B, C and D for renal aortic stenosis was 92.68%, 86.49%, 84.62% and 82.86%, respectively. The results confirmed that iterative reconstruction of IDose4 can reduce the dose of radiation and contrast agent and improve the quality of imaging. It has high feasibility and practicability in low dose CT renal angiography.
    Prognostic Value of SOFA Score Combined with Ultrasound in Sepsis Patients with AKI
    ZHANG Zhen'en, ZHENG Aidong, YAN Xixiang, SUN Xiaoyan
    2020, 38(2):  260-265.  DOI: 10.7517/issn.1674-0475.190906
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    This article mainly explores the prognostic value of SOFA score combined with ultrasound in patients with sepsis and acute kidney injury (AKI). Fifty patients with sepsis and AKI in our hospital from January 2017 to January 2019 were selected as the observation group and divided into AKI stages 1, 2 and 3. The 50 patients with sepsis admitted in the same period were used as the control group. All patients were evaluated by SOFA score and ultrasound. The results showed that the PDU score of the observation group was lower than that of the control group (P<0.05); the RI value and SOFA score were higher than that of the control group (P<0.05). The PDU scores and SOFA scores were different among the three group at different stages. With the increase of AKI stage, the decrease of PDU score and the increase of SOFA score (P<0.05), but the RI value was not different between the three groups (P>0.05); the in-hospital mortality rate of 50 patients with sepsis and AKI was 44.00%. Univariate analysis found that age, mechanical ventilation time, ICU length of stay, AKI stage, septic shock, SOFA score, and PDU score were factors affecting the poor prognosis of patients (P<0.05); AKI stage 3, septic shock occurred, SOFA score, and PDU score were independent factors of poor prognosis in patients with sepsis and AKI (P<0.05). The larger the area under the ROC curve (AUC), the better the predictive power for prognosis. When AUC>70.00%, it has Clinical Value. The combination of the two is significantly higher than the SOFA score (AUC=74.28%) or PDU score (P<0.001). The above results show that patients with sepsis and AKI who use SOFA scores and ultrasound for assessing the prognosis of patients are better than using SOFA scores or ultrasound alone, and the combined predictive value is greater.
    Analysis of the Diagnostic Value of 64-slice Spiral CT in the Degree of Coronary Artery Stenosis and Plaque Stability of T2DM Patients with Coronary Heart Disease
    WANG Chaobing, LI Xu, XU Pan, ZHAO Xia
    2020, 38(2):  266-271.  DOI: 10.7517/issn.1674.190907
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    The aim of this paper is to analyse the diagnostic value of 64-slice spiral CT in the degree of coronary artery stenosis and plaque stability of Type 2 diabetes mellitus(T2DM) patients with coronary heart disease. 90 patients with coronary heart disease received in our hospital from February 2015 to February 2018 were selected and divided into two groups. One is the observation group (n=49), which with the combination of T2DM, the other is the control group (n=41), which without the combination of T2DM. Soft plaque and mixed plaque in the observation group were significantly more than those in the control group, and calcified plaque were significantly less than those in the control group. There was no significant difference in grade Ⅰ, Ⅱ and Ⅳ coronary artery stenosis between the two groups (P>0.05). Grade Ⅲ stenosis in the observation group was significantly higher than that in the control group (P<0.05). The sensitivity of 64-slice spiral CT in diagnosing ≥ 50% coronary artery stenosis was the lowest, but it gradually increased with the pathological deterioration. The positive predictive value increased with the pathological deterioration, but all of them were lower than the negative predictive value, indicating that there was an overestimation in the evaluation of coronary artery lesions with 64-slice spiral CT. For the patients with relatively serious coronary artery calcification, the diagnostic specificity decreases with the increase of calcification degrees, but high sensitivity and accuracy can still be maintained. In conclusion, multi-slice spiral CT has a high diagnostic value for the degree of coronary artery stenosis and plaque stability in patients with T2DM complicated with coronary heart disease, which can help to provide correct diagnosis and select appropriate treatment plan in clinical practice.
    Value of Multi-slice Spiral CT Perfusion Imaging in Evaluating Interventional Thermochemotherapy for Advanced Hepatocellular Carcinoma
    CHEN Tingyu, WANG Tao, GONG Qiyun, WANG Heng, ZHANG Hongwei
    2020, 38(2):  272-279.  DOI: 10.7517/issn.1674-0475.190909
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    To investigate the application value of multi-slice spiral CT perfusion imaging (CTPI) in evaluating the efficacy of interventional thermal chemotherapy in the treatment of advanced liver cancer, we analyzed the CTPI perfusion parameters and serum oncology markers of 72 patients with middle and advanced liver cancer before and after interventional thermochemotherapy treatment. Compared with the data before treatment, it was found that the perfusion parameters of CTPI in the cancer foci were significantly improved after treatment, and the serum tumor markers were significantly decreased. The CTPI perfusion parameters and serum tumor markers showed statistically significant differences between the complete lipiodol depositon group and partial lipiodol depositon group, the same as between the objective remission group and non-remission group. Pearson correlation analysis showed a significant correlation between CTPI perfusion parameters and serum tumor markers of liver cancer patients. In conclusion, CTPI perfusion parameters can effectively reflect arterial blood supply changes in patients with advanced liver cancer before and after interventional thermal chemotherapy, providing a valuable reference for clinical efficacy evaluation.
    The Diagnostic Value of Transvaginal Doppler Color Ultrasound Combined with Serum Human Chorionic Gonadotropin in Cesarean Scar Pregnancy
    SHI Xinjing, KANG Zhiping, XING Longyan, LIU Yajing, CHEN Liru, YANG Dongxue
    2020, 38(2):  280-285.  DOI: 10.7517/issn.1674-0475.190910
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    This study was to investigate the diagnostic value of transvaginal Doppler color ultrasound combined with serum human chorionic gonadotropin (β-HCG) in cesarean scar pregnancy. From April 2018 to April 2019, 56 patients with suspected cesarean scar pregnancy in our hospital were selected as subjects. All of them were examined by transvaginal Doppler color ultrasound and serum β-HCG levels, and confirmed by surgery and/or histopathological examination. The results showed that the characteristics of transvaginal Doppler color ultrasound in patients with CSP included:the gestational sac was visible in the myometrium of lower front wall, thinning of the myometrium between the gestational sac and the bladder, high speed and low resistance signal around the gestational sac. The increase of serum β-HCG in 48 h in CSP patients was lower than that in non-CSP patients (t=7.425, P=0.000). The area under the ROC curve of the increase of serum β-HCG in 48 h was 0.919, and the optimal cut-off value was 64.22%. At this time, the sensitivity of diagnosis was 80.00%, and the specificity was 88.90%. Compared with surgery and/or pathological examination, the consistency of single diagnosis and combined diagnosis was good, and there was no difference in the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of CSP diagnosis,P>0.05. The two methods can be used as a reference to reduce the misdiagnosis rate and missed diagnosis rate.
    The Relationship Between Electrocardiogram Characteristics and Disease Classification, Prognosis for Patients with Acute Cerebral Infarction
    GUO Xiaoyun, WANG Jintao
    2020, 38(2):  286-290.  DOI: 10.7517/issn.1674-0475.190911
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    To explore the relationship between ECG characteristics and disease classification and prognosis for patients with acute cerebral infarction, 110 patients with acute cerebral infarction admitted to neurology department of our hospital from January 2016 to June 2019 were selected as research objects. All patients were given electrocardiogram examination. The abnormal rate of ECG was 72.73%, including ischemic ST-T changes(45.00%), sinus tachycardia(11.25%), ventricular premature beats (11.25%), atrial fibrillation(7.50%), atrial premature beats(6.25%) and left ventricular hypertrophy (6.25%). The abnormal rate of ECG in the slight-group was significantly lower than those in the medium-group and the severe-group (P<0.05). The abnormal rate of ECG in the large and the small infarction groups were significantly higher than those of the lacunar cerebral infarction group (P<0.05). The mortality rate of abnormal ECG group was significantly higher than that of normal ECG group (P<0.05).In conclusion, ECG abnormalities in patients with acute cerebral infarction are mainly manifested as ischemic ST-T changes, sinus tachycardia, ventricular premature beats, atrial fibrillation, atrial premature beats and left ventricular hypertrophy, and the abnormal rate has important evaluating value for disease classification and prognosis.
    Evaluation of the Relationship Between MMP-9, PAF, Lp-PLA2 and Coronary Plaque Properties Based on Dual-source CT Angiography
    LIU Feng, DENG Daping
    2020, 38(2):  291-295.  DOI: 10.7517/issn.1674-0475.190913
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    Coronary atherosclerotic heart disease is one of the common diseases that threaten health. In this study, I selected 206 patients with coronary heart disease diagnosed in our hospital from February 2017 to December 2018. Among them, there were 114 patients of acute coronary syndrome(ACS group) and 92 patients of stable angina pectoris(SAP group). The plaque properties of the patients were detected by dual-source CT angiography. The concentrations of serum MMP-9, PAF and Lp-PLA2 were measured in the laboratory, and the relationship between MMP-9, PAF, Lp-PLA2 and plaque properties was analyzed. The results showed that the plaque area and eccentricity index of the patients in the ACS group were larger than those in the SAP group (P<0.05). The levels of serum MMP-9, PAF and Lp-PLA2 in the ACS group were higher than those in the SAP group (P<0.05). The proportion of vulnerable plaques in the ACS group was significantly higher than that in the SAP group (P<0.05). The levels of serum MMP-9, PAF and Lp-PLA2 in all vulnerable plaques were higher than those in stable plaques, and the difference was statistically significant (P<0.05). The eccentricity index of coronary plaque was positively correlated with serum MMP-9, PAF and Lp-PLA2 concentrations (P<0.05). Therefore, the observation of coronary atherosclerotic plaque by dual-source CT angiography and serum MMP-9, PAF and Lp-PLA2 levels can be used to assess the patient's condition. Serum MMP-9, PAF and Lp-PLA2 concentrations are related to the nature and instability of plaque, which can provide a basis for predicting the nature of coronary plaque in patients.
    Diagnostic Performance of Contrast-enhanced Spectral Mammography in Dense Breasts Disease
    YANG Hang, ZHANG Xueqin, YUAN Yuan, LI Zhenlin, LIU Xijiao, YANG Jixue, HUANG Lin
    2020, 38(2):  296-300.  DOI: 10.7517/issn.1674-0475.190915
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    To compare the diagnostic performance of contrast-enhanced spectral mammography(CESM) with full-field digital mammography(FFDM) in dense breast disease, a total of 137 patients with proven dense breast who visited our department of breast surgery and pathologically confirmed from March 2017 to December 2018, were retrospectively enrolled in this study. All the patients underwent both FFDM and CESM examinations within one week. Using pathology results as the gold standard, sensitivity, specificity, positive prediction value(PPV),negative prediction value(NPV) and accuracy of dense breast disease by two methods were calculated,and the diagnostic efficacy of FFDM and CESM for dense breast diseases were compared. The results showed that a total of 140 lesions were detected in 137 patients, including 105 benign lesions and 35 malignant lesions. The CESM has significantly higher specificity, PPV, and accuracy in dense breast diseases than FFDM (P<0.05). It is suggested that compared with FFDM, CESM has better diagnostic efficacy of dense breast disease.
    Clinical Effect of Modified Panretinal Photocoagulation on Diabetic Retinopathy and Its Effect on Serum Level of Vascular Endothelial Growth Factor
    XU Jianlong, MA Qing
    2020, 38(2):  301-306.  DOI: 10.7517/issn.1674-0475.190916
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    To investigate the clinical effect of modified panretinal photocoagulation in the treatment of diabetic retinopathy (DR) and its effect on serum vascular endothelial growth factor (VEGF), this study selected 168 DR patients (212 eyes) admitted to our hospital from January 2018 to January 2019 were randomly divided into control group and observation group, 84 cases (106 eyes) in each group. The control group was treated with whole retina laser photocoagulation, while the observation group was treated with improved whole retina laser photocoagulation. The interval of photocoagulation therapy was 1 week, the treatment lasted 4 weeks. Following up for 6 months, the clinical effects of the two groups were observed; Before and after treatment, the best corrected visual acuity, intraocular pressure, retinal capillary non-perfusion area and regression of neovascularization were compared, and serum levels of vascular endothelial growth factor and ET-1 were compared. 6 months after treatment, the total effective rate of the observation group (92.45%) was significantly higher than that of the control group (75.47%), and the difference was statistically significant (P<0.05). There was no significant difference in the best corrected visual acuity and intraocular pressure between the two groups before and after treatment (P>0.05). Retinal capillary non-perfusion area and the regression rate of neovascularization in the observation group were significantly higher than those in the control group (P<0.05). The levels of serum VEGF and ET-1 in both groups were lower than those before treatment, and the levels of serum VEGF and ET-1 in the observation group were significantly lower than those in the control group (P<0.05). During the follow-up period, no serious complications such as visual acuity decrease, intraocular pressure increase, macular edema increase or vitreous hemorrhage occurred in both groups. The results show that, the modified panretinal photocoagulation is safe and effective in the treatment of DR. It is helpful to promote the regression of retinal non-perfusion area and neovascularization, reduce the level of vascular endothelial growth factor, improve the status of retinal ischemia and hypoxia, and control the further development of retinal lesions.
    Evaluation of Short-term Efficacy of Neoadjuvant Chemotherapy and Pathological Changes in Patients with Advanced Breast Cancer by DWI
    TONG Ying, MI Nan, ZHANG Rong, XING Qianchao, YANG Yueyun, WANG Shenglin
    2020, 38(2):  307-312.  DOI: 10.7517/issn.1674-0475.190919
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    In this study, to investigate the correlation between the result of diffusion weighted imaging (DWI) and neoadjuvant chemotherapy in locally advanced breast cancer, and to provide the imaging basis for the prognosis of locally advanced breast cancer, 72 patients with advanced breast cancer who underwent neoadjuvant chemotherapy in our hospital from February 2016 to February 2017 were divided into effective group and ineffective group according to the curative effect of chemotherapy. And patients were also divided into non-major histological response (NMHR) group and major histological response (MHR) group according to the pathological reactivity. Then the values of ADC before and after treatment were compared, and the correlation between tumor volume reduction and ADC value was analyzed. In 72 cases of advanced breast cancer patients treated with neoadjuvant chemotherapy, the treatment were effective in 45 cases. The effective rate is 62.50% (45/72), and the ineffectiveness rate was 37.50% (27/72). After the chemotherapy, there were 43 cases of MHR and 29 cases of NMHR. The tumor volume in the effective group was significantly smaller than that in the ineffective group, and the tumor volume in the MHR group was significantly smaller than that in the NMHR group (P<0.05). The ADC value of the four groups before treatment showed no significant difference (P>0.05), and were all increased after treatment. Moreover, the ADC value of effective group and MHR group were higher than that in the ineffective group and NMHR group respectively (P<0.05). The added ADC value between groups showed a significant difference (P<0.05). Tumor volume was negatively correlated with ADC value, and tumor volume reduction value was positively correlated with the ADC added value. This study showed that the ADC value of DWI was negatively correlated with the tumor volume in patients with advanced breast cancer, which can effectively evaluate the short-term efficacy and pathological changes of neoadjuvant chemotherapy.
    Analysis of the Effect of Acoustic Contrast-enhanced Ultrasound on Left Ventricular Thickness Measuring
    TIAN Miao, XUE Jingling
    2020, 38(2):  313-317.  DOI: 10.7517/issn.1674-0475.190923
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    In order to explore the effect of acoustic contrast-enhanced evaluation on left ventricular thickness and improve the accuracy of clinical measurement of wall thickness, 94 patients with cardiology were selected as subjects from January 2018 to May 2019. The patients were divided into two groups according to the random number table method. The control group (47 cases) received two-dimensional echocardiography. The observation group (47 cases) received left heart contrast echocardiography. The left ventricular wall was divided into 18 segments, and the difference in accuracy between the two groups was compared. There were significant differences in the wall thickness between the two groups in the apical two-chamber (A2CH) section and the 3rd, 6th, 15th, and 18th stages of systolic phase (P<0.05). There were significant differences between the two groups in the wall thickness of the 4th, 10th, 13th and 16th stages of apical period and the 4th, 10th and 16th stages of systolic phase in the apical three-chamber (A3CH) section (P<0.05). There were significant differences in the wall thickness of the 5th, 14th stages of the apical period of the apical four-chamber view (A4CH) and the 5th, 17th stages of the systolic phase between the two groups (P<0.05). Two-dimensional echocardiography has accurate and reliable measurements in the 1st, 2nd, 7th, 8th, and 11th segments of the diastolic phase and the 1st, 2nd, 7th, 8th, 9th, 11th, 12th, 13th, and 14th segments of the systolic phase, while the left cardiac echocardiography can provide a more accurate left ventricular thickness index, which is of great significance to improve the accuracy of clinical detection of left ventricular wall thickness.
    Guiding Value of Bronchial Artery CTA Examination before Interventional Therapy in Patients with Central Lung Cancer
    WANG Xiaoyan, XIAO Jiwei
    2020, 38(2):  318-322.  DOI: 10.7517/issn.1674-0475.190924
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    To investigate the guiding value of bronchial artery CT angiography (CTA) in patients with central lung cancer before interventional therapy, 56 patients with central lung cancer who underwent bronchial artery CTA examination in our hospital due to recurrent hemoptysis of lung cancer were selected as the research object, and another 15 cases of normal control group in the same period were selected, in this study. All patients underwent bronchial artery embolization, and the results of CTA imaging were compared. The results showed that, the development rate of L bronchial artery in patients with left lung cancer and R bronchial artery in patients with right lung cancer were significantly higher than those in control group (P<0.05). The diameter of L and R bronchial artery in left and right lung cancer patients was significantly higher than that in control group (P<0.05). Grade 4 was the main type of bronchial artery anatomy in patients with left lung cancer, accounting for 72.2%. Grade 1 was the main type of bronchial artery anatomy in right lung cancer patients, accounting for 47.4%. A total of 76 hemoptysis arteries were detected, including 58 bronchial arteries, 10 pulmonary circulation arteries, 6 anastomotic arteries and 2 intercostal arteries. In 28 patients with lung cancer, the blood supply bronchial artery of patients had at least one bend angle less than 90°, which was circuitous. CTA showed dotted or reticular neoplasm vessels with narrow inner pulmonary artery, and pleural thickening adjacent to the lesion in some patients with extrapulmonary circulation participating in blood supply. This study shows that, CTA examination can effectively provide the branch type, anatomical classification and opening position of tracheal artery, better observe the source of blood supply of pulmonary diseases, and provide reference for interventional treatment of patients.
    Clinical Value of Transrectal Ultrasound Combined with Prostate Specific Antigen Density in the Diagnosis of Prostate Cancer
    FENG Liang, SHI Lin, JIANG Yimin
    2020, 38(2):  323-327.  DOI: 10.7517/issn.1674-0475.190925
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    To investigate the clinical value of transrectal ultrasound combined with prostate specific antigen density (PSAD) in the diagnosis of prostate cancer, 97 patients with elevated PSA from September 2013 to September 2018 were enrolled in the study. All patients were examined by transrectal ultrasound and PSAD, compared with the pathological results. The PSAD inspection results were observed, and the diagnosis coincidence rate of transrectal ultrasound+PSAD and the pathological examination was analyzed. Then the accuracy, sensitivity and specificity of the the transrectal ultrasonography combined with PSAD were compared with those of pathological examination. Finally, the imaging features and internal echo of transrectal ultrasonography in patients with prostate cancer were analyzed. The detection rate of prostate cancer, transitional cell carcinoma and mucinous adenocarcinoma by transrectal ultrasound and PSAD was slightly lower than pathological examination (P>0.05). The accuracy, sensitivity and specificity of transrectal ultrasound combined with PSAD were slightly lower than those of pathological examination (P>0.05). According to the ultrasound image, the cancer can be divided into three types:diffuse, nodular and no nodular. The imaging characteristics and internal echo of different types are different. It is indicated that the accuracy of transrectal ultrasound combined with PSAD in the diagnosis of prostate cancer is high, which can clearly reflect the internal echo of different disease types. It is worth popularizing because of its high clinical practical value.
    The Relationship between Measurement of 1.5 T MRI and the Diagnosis and Classification of Disposable Lateral Dislocation of Patella
    HU Xiaoming, YAO Jun
    2020, 38(2):  328-332.  DOI: 10.7517/issn.1674-0475.190926
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    This study analyzed the relationship between TT-TG, PH, SA, SD measured by MRI and the diagnosis and classification of TLPD patients. Fifty TLPD patients admitted to our hospital from January 2018 to February 2019 were taken as the control group and 50 normal knee joints as the control group. TT-TG, PH, SA and SD levels were measured by 1.5 T MR imaging, and the diagnostic value of the indices used alone and in combination was analyzed, and the relationship between the indices and clinical classification was analyzed. The results show:the levels of TT-TG, PH and SA in the observation group were significantly higher than those in the control group (P<0.05), and the SD level in the observation group was significantly lower than that in the control group (P<0.05). The combined application of TT-TG, PH, SA and SD indicators could significantly improve the sensitivity, specificity and accuracy of TLPD diagnosis (P<0.05). The combined use of AUC with the four indicators was significantly higher than that of individual use, and the difference was statistically significant (P<0.05); with the deterioration of patients'Dejour classification, TT-TG, PH and SA levels were significantly increased, SD levels were significantly reduced, and the difference was statistically significant (P<0.05); TT-TG, PH, SA and SD were influencing the clinical manifestations of TLPD patients. The independent influencing factors of typing (P<0.05). This study demonstrated that measuring TT-TG, PH, SA and SD with 1.5 T MRI can effectively improve the clinical diagnostic value of TLPD patients, and TT-TG, PH, SA and SD are independent influencing factors of clinical classification.
    A Comparative Study on the Clinical Application of MRA and CTA Digital Three-dimensional Model of Abdominal and Pelvic Vessels in Placenta Implantation
    YUAN Qiang, ZENG Yanni, TAN Minyi, QIN Yiwei, HONG Yong
    2020, 38(2):  333-338.  DOI: 10.7517/issn.1674-0475.190927
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    To construct the digitalized 3 dimensional(3D) model of the pelvic and abdominal vessels by CTA and MRA original images, and assess the guiding effect on the treatment of placenta implantation, 40 cases patients with placenta implantation pregnant women from January 2018 to January 2019 were selected, and divided into 2 groups according to the random number table. The control group received interventional therapy guided by CTA, and the observation group received interventional surgery guided by MRA. The 3D model of abdominal and pelvic vessels of the two groups were analyzed, and the X-ray radiation dose and contrast agent dosage were calculated. The incidence of postoperative complications was also calculated. Results showed both of the methods could clearly display the third-grade arteriovenous vessels, and reconstruct them completely. CE-MRA was superior to CTA in presacral vein display (P<0.01). The interposition time, exposure time, X-ray radiation, contrast agent dose and contrast agent rate in the observation group were lower than those in the control group (P<0.05). The incidence of complications in the observation group was significantly lower than that in the control group (P<0.01). The digitalized 3 dimensional(3D) model by MRA can clearly display the first to fourth grade arteriovenous vessels, which is more suitable for the interventional treatment of placental implantation.
    The Value of Transabdominal Combined Transvaginal Color Doppler Ultrasonography in Evaluating the Pernicious Placenta Previa Complicated Placenta Implantation
    WANG Jiali, HU Jian, YANG Fan, JIANG Yaqiong, LI Li
    2020, 38(2):  339-343.  DOI: 10.7517/issn.1674-0475.190928
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    The value of transabdominal combined transvaginal color Doppler ultrasonography in evaluating the pernicious placenta previa (PPP) complicated placenta implantation was analyzed in this study. 172 patients with PPP from June 2017 to June 2019 were selected as the subjects of this study, all patients were examined by transabdominal and transvaginal color Doppler ultrasonography. The evaluation value of transabdominal and transvaginal color Doppler ultrasonography and their combination to PPP complicated placenta implantation was analyzed. The postpartum pathological results showed that among 172 patients with PPP, 120 patients (69.77%) were complicated placenta implantation, and 52 patients (30.23%) were not omplicated placenta implantation. In the sensitivity, specificity and accuracy of evaluating the PPP complicated placenta implantation, the transabdominal color Doppler ultrasonography were 76.67%, 73.08% and 75.58%, the transvaginal color Doppler ultrasonography were 83.33%, 80.77% and 82.56%, the transabdominal combined transvaginal color Doppler ultrasonography were 96.67%, 96.15% and 96.51%, the transabdominal combined transvaginal color Doppler ultrasonography were significantly higher than the transabdominal and transvaginal color Doppler ultrasonography, the difference was statistically significant (P<0.05). This study confirms that, Transabdominal and transvaginal color Doppler ultrasonography are the effective methods for evaluating the PPP complicated placenta implantation, and their combined evaluation value is higher, it's worth for further clinical promotion.
    Analysis of the Application Value of Dual-source CT and MRI in the Diagnosis of Gouty Arthritis
    LI Chunlei, QING Guangjun, WANG Rongfen, PENG Ke
    2020, 38(2):  344-349.  DOI: 10.7517/issn.1674-0475.191003
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    100 patients with gouty arthritis who were treated in our hospital from May 2017 to May 2019 were enrolled. All patients underwent dual-source CT and MRI. In this study, we compared the positive diagnostic rate and the diagnostic sensitivity of dual-source CT and MRI, as well as the image differences in two methods(including tophus, joint bone damage, articular cartilage damage, joint effusion, peripheral edema, synovial damage and urate crystal). The aim was to explore the value of dual-source CT and MRI in the diagnosis of patients with gouty arthritis. The results showed that the positive rate and diagnostic sensitivity of dual-source CT were higher than that of MRI, and the difference was statistically significant. Dual-source CT had a higher detection rate for tophus and bone destruction than MRI, and the difference was statistically significant. Dual-source CT has high specificity in detecting urate crystals. In examination of joint effusion, synovium and cartilage change, MRI has higher detection rates than dual-source CT, and the difference was statistically significant. The above results indicate that dual-source CT is specific in diagnosing urate crystals. The application value of dual-source CT in the diagnosis of gouty arthritis is higher than MRI.
    Early Predictive Value of Acoustic Radiation Force Impulse Imaging in Concurrent Radiotherapy and Chemotherapy for Cervical Cancer
    WU Jie
    2020, 38(2):  350-355.  DOI: 10.7517/issn.1674-0475.191004
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    To investigate the early predictive value of acoustic radiation force impulse imaging (ARFI) technique in concurrent radiotherapy and chemotherapy for cervical cancer, in this study, 57 patients with cervical cancer diagnosed by pathological examination in our hospital from January 2018 to June 2019 were selected. All patients were treated with concurrent radiotherapy and chemotherapy. Before treatment, 2 weeks after treatment and at the end of treatment, the patients were examined with GE LOGIQ E9 color Doppler ultrasound diagnostic instrument. The elastic image score, strain ratio and shear wave velocity were measured and recorded. The results showed that, After concurrent chemoradiotherapy, 66.67% patients had complete remission (CR) (38/57), 33.33% patients had partial remission (PR) (19/57), no progress and stable patient. Before treatment, there were significant differences in elastic image score and shear wave velocity between CR group and PR group (P<0.05), there was no significant difference in elastic strain ratio between CR group and PR group (P>0.05). With the progress of treatment, the elastic image score,strain ratio and shear wave velocity of lesions in CR group and PR group decreased gradually. After 2 weeks of treatment and at the end of treatment, the elastic image score, strain ratio and shear wave velocity of lesions in CR group and PR group were lower than those before treatment, and CR group was lower than PR group, the difference was statistically significant (P<0.05). According to this, the elastic image score, strain ratio and shear wave velocity were continuously monitored by ARFI technique in the early stage, to reflect the effect of concurrent radiotherapy and chemotherapy for cervical cancer, it has a certain early predictive value for the efficacy of concurrent radiotherapy and chemotherapy for cervical cancer.
    Application of Multiplanar Reconstruction of MSCT in the Diagnosis of Gastrointestinal Lymphoma and Its Correlation with Clinical Stage
    WU Xiao, ZHAO Baojun
    2020, 38(2):  356-361.  DOI: 10.7517/issn.1674-0475.191005
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    In order to study the application value of multiplanar reconstruction of MSCT in the diagnosis of gastrointestinal lymphoma and the correlation between the detection results and clinical stages, 50 cases of gastrointestinal lymphoma confirmed by pathological examination in our hospital from January 2016 to June 2019 were selected as the observation group, and 50 cases of non-gastrointestinal lymphoma were selected as the control group, all of them were implemented with MSCT multiplanar reconstruction. We compared the difference of CT reconstruction parameters (image objective noise, signal-to-noise ratio) between the two groups. We also compared the difference of CT reconstruction parameters of different tissue types and clinical stages in observation group. And we tested the correlation between CT reconstruction parameters and clinical stages of gastrointestinal lymphoma by Pearson correlation analysis. Pathological examination showed that there were 25 cases of diffuse large B-cell lymphoma, 19 cases of mucosa related lymphoma, 4 cases of small B-cell lymphoma and 2 cases of mantle cell lymphoma in 50 cases of gastrointestinal lymphoma. There was no significant difference in the coincidence rate of pathological results and multiplanar reconstruction results of MSCT (P>0.05). The objective noise of the image in the observation group was lower than that in the control group, and the signal-to-noise ratio was higher than that in the control group (P<0.05). There was significant difference in CT reconstruction parameters of different tissue types and clinical stages in the observation group (P<0.05). The results of Pearson correlation analysis showed that the image objective noise in multiplanar reconstruction parameters of MSCT was negatively correlated with the clinical stage of gastrointestinal lymphoma (r=-0.74, P< 0.05), and the signal-to-noise ratio was positively correlated with the clinical stage of gastrointestinal lymphoma (r=0.71, P<0.05). Therefore, this paper showed that in the diagnosis of gastrointestinal lymphoma, multi-slice spiral CT multiplanar reconstruction has a better effect, and the CT reconstruction parameters are closely related to the clinical stage, which has an important reference value for the identification of tissue type and clinical stage.
    Imaging Characteristics and Related Factors of Patients with Cerebral Infarction after Cardiac Surgery
    BAHTIYAR·keram, LI Jian, ZHANG Daquan
    2020, 38(2):  362-367.  DOI: 10.7517/issn.1674-0475.191006
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    The imaging features of cerebral infarction patients after cardiac surgery and related factors of cerebral infarction were discussed. 286 cases of cardiac surgery patients were selected as the study subjects. 34 cases of cerebral infarction occurred after operation. According to different surgical methods, the patients with cerebral infarction were divided into 11 cases of cardiopulmonary bypass group and 23 cases of non-extracorporeal circulation group. The imaging features of postoperative cerebral infarction were compared between the two groups, and the influencing factors of cerebral infarction after cardiac surgery were analyzed. The results showed that there was no significant difference in the incidence of perforation, watershed infarction, multiple infarction, and old infarction between the two groups (P>0.05). The incidence of cortical infarction in the extracorporeal circulation group was significantly lower than that in the non-extracorporeal circulation group. The incidence of large infarction and bilateral infarction in the extracorporeal circulation group was significantly higher than that in the non-extracorporeal circulation group, and the difference was statistically significant (P<0.05). Univariate analysis showed that gender, fasting blood glucose, TC, TG, LDL-C, Hcy, smoking, and drinking were not the influencing factors of cerebral infarction after cardiac surgery (P>0.05); age, education level, history of hypertension, diabetes as heart Influencing factors of cerebral infarction after surgery (P<0.05); multivariate binary logistic regression analysis, high age, low education, history of hypertension ≥ 10, diabetes was an independent influencing factor of cerebral infarction after cardiac surgery (P< 0.05). This article shows that extracorporeal circulation surgery is often a large area of infarction, bilateral infarction, heavier symptoms, non-extracorporeal circulation surgery is often cortical infarction, and both watershed infarction, more related to embolism and hypoperfusion. Cerebral infarction after cardiac surgery is closely related to high age, low level of education, history of hypertension ≥ 10, and diabetes. Early targeted prevention intervention may reduce the incidence of cerebral infarction.
    Analysis of the Effect of IVIM Quantitative Analysis on Differential Diagnosis of Different Molecular Types of Breast Cancer
    WANG Lin, CHEN Xiangrong, XU Shuhui, LIAN Tao, LIN Qiansen, YU Meiying
    2020, 38(2):  368-375.  DOI: 10.7517/issn.1674-0475.191018
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    To evaluate the application value of IVIM-DWI in differentiating different molecular subtypes of breast cancer. The clinical data of 121 patients with breast cancer who were hospitalized in our hospital from July 2016 to March 2019,and 32 patients with benign breast masses were retrospectively analyzed. All patients underwent MRI assessment and IVIM-DWI imaging. The ADC value and the IVIM-DWI multi-parameter values were obtained.The quantitative detection of ADC and IVIM-DWI multiple parameter values among different molecular subtypes of breast cancer was compared. (1) The ROC curve shows that in the identification of benign and malignant breast lumps, The area under the curve of D value is larger than ADC, D* and f (P<0.05); The area under the curve predicted by the four indexes was significantly higher than that predicted by the four indexes alone (P<0.05).(2) The D value in the tumor tissues of the ER and PR negative groups was lower than that of the positive group, and the D* value was higher than that of the positive group (P<0.05). The ADC value and D value in the tumor tissues of Ki67<14% group were higher than those in Ki67 ≥ 14% group, and the D* value was lower than that in Ki67 ≥ 14% group (P<0.05); In the HER-2 positive group tumor, the f value in the tissue was higher than that in the HER-2 negative group (P<0.05); (3) There were differences in ADC value, D value, D* value and f value between different types of breast cancer, among which the three negative breast cancer group showed lower ADC value, D value and higher f value (P<0.05). IVIM is a valuable magnetic resonance technique that can be used to identify benign and malignant breast masses and to differentiate breast cancer molecular subtypes. Understanding the characteristics of breast cancer through IVIM parameters provides a new way to accurately assess breast cancer.