Abstract: In this study, 132 patients of myocardial infarction with acute ST-segment elevation in our hospital from October 2017 to February 2019 were selected as research objects. According to the results of coronary angiography, the patients were divided into the single-vessel lesion group (50 cases), the double-vessels lesion group (45 cases) and the three-vessels lesion group (37 cases). The changes of ECG T-wave, N-proBNP level in plasma, Gensini score level were compared in the three groups, as well as the correlation between lesion number and various indicators. The results showed that there were significant differences in the N-proBNP level, left ventricular ejection fraction and Gensini level between the three groups (P<0.05). The differences of continuous T-wave inversion between the groups were statistically significant (P<0.05). The number of lesions was positively correlated with T-wave, N-proBNP level and Gensini score. Multivariate logistic regression analysis showed that N-proBNP level, Gensini score and age were independent influencing factors of cardiac dysfunction in patients with heart infarction. These results suggested that the more pathological vessels in patients with myocardial infarction, the higher changes of ECG T-wave, N-proBNP level and Gensini score. The N-proBNP level in plasma and Gensini score could be used as prognostic factors for patients with myocardial infarction.

Key words: acute myocardial infarction, N-proBNP in plasma, Gensini score