Effects of Coronary Artery Stenosis Degree on Ventricular Repolarization Indexes in Patients with Coronary Heart Disease

doi:10.7517/issn.1674-0475.211208

Abstract

Abstract: The purpose of this study was to investigate the effect of coronary artery stenosis degree on ventricular repolarization indexes. Chosen 105 patients with coronary heart disease as observation group, including 63 cases of acute coronary syndrome (ACS) and 42 cases of stable angina pectoris (SAP), and chosen 60 patients with non coronary heart disease were selected as the control group. The differences of ECG and cardiac ultrasound parameters between the two groups were compared. QTV, QTc interval, TpTe, TpTe/QT, left atrial diameter, left ventricular posterior wall thickness, ventricular septal thickness and left 625 ventricular end diastolic diameter in the observation group were significantly higher than those in the control group (P<0.05), while the left ventricular ejection fraction was significantly lower than that in the control group (P<0.05). In observation group the TpTe, TpTe/QT and left atrial diameter of ACS patients were significantly higher than those of SAP patients (P<0.05), while the left ventricular ejection fraction was significantly lower than that of SAP patients (P<0.05). The QTV, QTc interval, TpTe, TpTe/QT and left ventricular end diastolic diameter of patients with severe stenosis in the observation group were significantly higher than those in patients with mild to moderate stenosis (P<0.05), while the left ventricular ejection fraction was significantly lower than those of patients with mild to moderate stenosis (P<0.05). Gensini score was positively correlated with QTV, QTc interval, TpTe and TpTe/QT (P<0.05), but negatively correlated with left ventricular ejection fraction (P<0.05). The area under ROC curve of QTV, QTc interval, TpTe, TpTe/QT combined with left ventricular ejection fraction in predicting severe stenosis was 0.931, P<0.05. The degree of coronary artery stenosis in coronary heart disease is positively correlated with ventricular repolarization index, ventricular repolarization index has a certain value in predicting the degree of stenosis.

Key words: coronary heart disease, degree of coronary artery stenosis, ventricular repolarization index, relevance

LI Dongmei, LIU Lianghua, MO Yanli, HUANG Junzhang. Effects of Coronary Artery Stenosis Degree on Ventricular Repolarization Indexes in Patients with Coronary Heart Disease[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2022, 40(3): 625-630.

References

[1] 胡倩, 刘佳, 岳庆雄. 超声心动图心肌收缩早期延迟时间指标对判断冠状动脉狭窄程度的价值[J]. 中国循环杂志, 2019,34(10):974-978.
[2] 石亚君, 陈韵岱, 郜玲, 等. 冠状动脉CT成像和平板运动试验对冠心病的诊断价值[J]. 中华老年心脑血管病杂志, 2011,13(5):401-403.
[3] 张萍, 邹长林, 黄伟剑. Tp-Te间期和QTd在预测冠心病恶性心律失常中的价值研究[J]. 医学研究杂志, 2013,42(3):94-97.
[4] 国际心脏病学会和协会及世界卫生组织命名标准化联合专题组. 缺血性心脏病的命名及诊断标准[J].中华心血管病杂志, 1981,9(1):75.
[5] Gensini G G. A more meaningful scoring system for determining the severity of coronary heart disease[J]. The American Journal of Cardiology, 1983,51(3):606.
[6] Krishnamurthy G, Menon A, Kannan K, et al. Coronary artery disease and mesenteric artery stenosis - Two sides of the same coin? - Long term prospective analysis[J]. Intractable & Rare Diseases Research, 2019,8(4):245-251.
[7] 李赵欢, 唐红. 二维超声心动图和M型超声心动图评价左心室扩大患者左心室收缩功能的对比研究[J]. 生物医学工程与临床, 2009,13(3):214-217.
[8] 延东娥, 高赟, 陈新云, 等. 二维斑点追踪超声心动图评估冠状动脉病变对收缩早期左心室心肌运动的影响[J]. 中国医学影像技术, 2020,36(1):68-71.
[9] 李媛媛, 潘存雪, 刘文亚, 等. 双能量冠脉CTA评价急性心肌梗死的动物实验研究[J]. 中国医学计算机成像杂志, 2019,25(3):321-325.
[10]詹正学, 蒋世月, 李静. 丹红注射液联合氧化苦参碱治疗冠心病心绞痛的疗效及对心率变异性、Q-T离散度、心肌缺血总负荷的影响[J]. 中华中医药学刊, 2020,38(7):60-63.
[11] 徐伟华. 多层螺旋CT血管造影对冠状动脉粥样硬化性心脏病患者冠脉狭窄程度及斑块稳定性的评价[J]. 影像科学与光化学, 2020,38(3):491-495.
[12] 赵娜, 高扬, 徐波, 等. 基于冠状动脉CT血管成像的狭窄率与斑块特征联合分析对提高CT诊断心肌缺血效能的价值[J]. 中华放射学杂志, 2021,55(1):40-47.
[13] 葛丽丽, 李玉宏. 经超声测量心外膜脂肪组织厚度对冠心病患者冠状动脉狭窄程度的预测[J]. 中国老年学杂志, 2020,40(10):2017-2019.
[14] 李名鹏, 王仲华, 钟丹丹, 等. 冠心病患者PCI术前血清LOX-1、Vaspin水平变化及其对病变冠状动脉术后再狭窄的预测效能[J]. 山东医药, 2020,60(6):65-68.
[15] 张放, 安浩君, 李霞, 等. 冠心病患者血清γ-谷氨酰转肽酶水平与Gensini评分的相关性研究[J]. 中国全科医学, 2014,17(35):4166-4169.