Abstract: This study investigated the application of dynamic contrast-enhanced MRI and CT in the differential diagnosis of adrenal adenoma and metastasis. 73 patients with adrenal tumors were divided into adrenal adenoma group and adrenal metastasis group according to the type of adrenal tumors. All of patients underwent DCE MRI and CT. The relevant parameters were recorded to analyze the tumor clearance rates based on MRI examination with CT clearance rate at each time point. There were significant between-group differences about tumor size and morphology, T2WI signal, enhancement degree and plain scan CT value (P<0.05). After 3 min, 5 min, 7 min and 9 min of injection, CT clearance rates between groups were significantly different (P<0.05). After 5 min, 7 min and 9 min of injection, MRI clearance rate were positively correlated with CT clearance rate. Dynamic contrast-enhanced MRI and CT examination is important to differential diagnosis of adrenal adenoma and metastasis.

Key words: adrenal adenoma, adrenal metastases, magnetic resonance imaging, computed tomography