IMAGING SCIENCE AND PHOTOCHEMISTRY ›› 2022, Vol. 40 ›› Issue (6): 1449-1454.DOI: 10.7517/issn.1674-0475.220808

• Review and Articles • Previous Articles     Next Articles

Application of CEUS Combined with Conventional US in the Diagnosis of Thick-walled Gallbladder Lesions and Gallbladder Polypoid Lesions

XIANG Shufang, ZHANG Mei, WANG Shouneng, LIU Wen, LIU Can   

  1. Department of Ultrasound, The First People's Hospital of Jingzhou, Jingzhou 434000, Hubei, P. R. China
  • Received:2022-08-07 Online:2022-11-23 Published:2022-11-15

Abstract: This article discussed the value of contrast-enhanced ultrasonography (CEUS) combined with conventional ultrasonography (US) in the diagnosis of thick-walled gallbladder lesions and gallbladder polypoid lesions. Forty-six patients with thick-walled gallbladder lesions and 60 patients with gallbladder polypoid lesions were selected. The clinical data, CEUS and US imaging features of patients were analyzed, and the diagnostic value of CEUS combined with conventional US was analyzed. The thickness of gallbladder wall, the proportion of discontinuous inner and outer gallbladder walls, and the proportion of high enhancement in patients with thick-walled gallbladder malignant lesions were higher than those in benign lesions (P<0.05), while the onset time and resolution time were faster than those in benign lesions (P<0.05). The patients with malignant gallbladder polypoid lesions had blood flow, unclear boundary with the cyst wall, and the proportion of gallbladder wall discontinuity was higher than that of benign lesions (P<0.05), and the time of onset and regression was faster than that of benign lesions (P<0.05). The Kappa value of CEUS combined with conventional US in the diagnosis of benign and malignant thick-walled gallbladder lesions was 0.870 (P<0.05), and the consistency was high. The sensitivity, specificity and accuracy of diagnosing malignant lesions were 91.67%, 95.45% and 93.48%, respectively. The Kappa value of CEUS combined with conventional US in the diagnosis of benign and malignant gallbladder polypoid lesions and pathological results was 0.832 (P<0.05), and the consistency was high. The sensitivity, specificity and accuracy of diagnosing malignant lesions were 90.91%, 92.59% and 91.67%, respectively. CEUS combined with conventional US has good application value in the diagnosis of benign and malignant thick-walled gallbladder lesions and benign and malignant gallbladder polypoid lesions.

Key words: contrast enhanced ultrasound, conventional ultrasound, thick walled gallbladder disease, polypoid lesion of gallbladder