Silicon Nanowire Arrays as Electrochemical Biosensors for Cytochrome c

doi:10.7517/j.issn.1674-0475.2009.02.87

Imaging Science and Photochemistry ›› 2009, Vol. 27 ›› Issue (2): 87-94.DOI: 10.7517/j.issn.1674-0475.2009.02.87

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Silicon Nanowire Arrays as Electrochemical Biosensors for Cytochrome c

YANG Kun^1,2, CHEN Huan^1,2, ZHAO Wen-chao^1,2, WANG Jian-tao^1,2, WANG Hui¹, ZHANG Xiao-hong¹

1. Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China;
2. Graduate University of the Chinese Academy of Sciences, Beijing 100039, P.R. China

Received:2008-06-12 Revised:2008-07-02 Online:2009-03-23 Published:2009-03-23

Abstract

Abstract: The direct electrochemical biosensor for cytochrome c based on the silicon nanowire arrays was fabricated.The silicon nanowire arrays were prepared from the etched silicon wafer,which were then treated with aqua regia and HF to remove the cladding silicon oxide sheath.The modified silicon nanowire arrays were further used as the electrode for fabricating the direct electrochemical biosensors for the detection of cytochrome c,which exhibited linear response to cytochrome c at low concentration and high sensitivity of 2.75 μA·mmol^-1·L due to the vast surface-to-bulk ratio of the silicon nanowire arrays and the interaction between the carboxyl group of cytochrome and Si-H group provided by the surface of the modified silicon nanowire arrays.

Key words: silicon nanowire arrays, electrochemical biosensors, cytochrome c

CLC Number:

YANG Kun, CHEN Huan, ZHAO Wen-chao, WANG Jian-tao, WANG Hui, ZHANG Xiao-hong. Silicon Nanowire Arrays as Electrochemical Biosensors for Cytochrome c[J]. Imaging Science and Photochemistry, 2009, 27(2): 87-94.

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Silicon Nanowire Arrays as Electrochemical Biosensors for Cytochrome c

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