B-spline Free-form Deformation Based 3-D Non-rigid Registration of Medical Images

doi:10.7517/j.issn.1674-0475.2014.02.200

Imaging Science and Photochemistry ›› 2014, Vol. 32 ›› Issue (2): 200-208.DOI: 10.7517/j.issn.1674-0475.2014.02.200

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B-spline Free-form Deformation Based 3-D Non-rigid Registration of Medical Images

FENG Zhaomei^1,2,3, DANG Jun¹, CUI Yaoyao¹, JIAO Yang¹

1. Suzhou Institute Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, Jiangsu, P.R. China;
2. Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130000, Jilin, P.R. China;
3. University of Chinese Academy of Sciences, Beijing 100049, P.R. China

Received:2013-09-17 Revised:2013-11-06 Online:2014-03-15 Published:2014-03-15

Abstract

Abstract:

Ultrasound imaging has been widely used because of its inherent advantages compared with others imaging modalities. It plays a positive role in clinical diagnosis, monitoring and surgery. Three-dimensional medical images could clearly show the size, shape of the lesion and provide relatively complete three-dimensional structure information of human tissue. In this paper, a non-rigid registration based on B-spline free form deformation for three-dimensional ultrasound (US) and Computed Tomography Compared (CT) was studied with thin-plate spline energy constraint solving image cross and overlap. In addition, we took relative overlap, mutual information and computation time as evaluation criteria to evaluate the performance of nonrigid registration algorithm for breast phantom images and clinical images. The demons method took an average of 1896 seconds, the improved algorithm took an average of 195 seconds, the efficiency increased by 8.7 times. The relative overlap was 89.58 percent of the original algorithm and the relative overlap was 91.35 percent of the improved algorithm, the accuracy was increased by 2.0 percent. The experiment results showed that the algorithm could achieve better registration results.

Key words: non-rigid registration, mutual information, free form deformation, ultrasound image, CT image

FENG Zhaomei, DANG Jun, CUI Yaoyao, JIAO Yang. B-spline Free-form Deformation Based 3-D Non-rigid Registration of Medical Images[J]. Imaging Science and Photochemistry, 2014, 32(2): 200-208.

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B-spline Free-form Deformation Based 3-D Non-rigid Registration of Medical Images

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