医源性电离辐射剂量率估算与生物医学防护研究

doi:10.7517/issn.1674-0475.211135

影像科学与光化学 ›› 2022, Vol. 40 ›› Issue (3): 469-473.DOI: 10.7517/issn.1674-0475.211135

医源性电离辐射剂量率估算与生物医学防护研究

董亚军¹, 程强力²

1. 南华大学附属第二医院, 湖南衡阳 421001;
2. 南华大学附属第一医院, 湖南衡阳 421001

收稿日期:2021-11-15 出版日期:2022-05-15 发布日期:2022-05-27

The Dose Rate Estimation and Medical Biomedical Protection of Iatrogenic Ionizing Radiation

DONG Yajun¹, CHENG Qiangli²

1. The Second Affiliated Hospital of University of South China, Hengyang 421001, Hunan, P. R. China;
2. The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan, P. R. China

Received:2021-11-15 Online:2022-05-15 Published:2022-05-27

摘要/Abstract

摘要： 医学影像拍摄过程中遭受的医源性电离辐射剂量可能诱发癌症,如何准确地估算出剂量率,降低医源性电离辐射技术误差,本文提出一种医源性电离辐射剂量率估算与生物医学防护研究方法。利用放射事故剂量的相关理论结合可供剂量得到估算所需参数信息,构建人体干细胞的存活模型后,采用无源效率刻度方法结合转换系数估算器官剂量;通过所测量的空气比释动能估算全身有效剂量,快速估算医源性电离辐射剂量率。通过质量保证方法与统计学方法对比验证所得判断假设的辐射情况是否与实际相同。实验结果表明:该方法能够快速、准确地实现医源性电离辐射剂量率估算,并且及时给出对应生物医学防护措施。

关键词: 医源性电离辐射, 剂量率估算, 质量保证, 统计学, 辐射效应, 辐射损伤, 生物医学防护

Abstract: The dose of iatrogenic ionizing radiation suffered in the process of medical image shooting may induce cancer. How to accurately estimate the dose rate and reduce the technical error of iatrogenic ionizing radiation, this paper proposes a research method of dose rate estimation of iatrogenic ionizing radiation and medical biomedical protection. After constructing the survival model of human stem cells, the organ dose was estimated by passive efficiency calibration method combined with conversion coefficient, through the relevant theory of radiation accident dose to combine the available dose to obtain the parameter information required for estimation. The whole body effective dose was estimated by the measured air specific release kinetic energy, and the dose rate of iatrogenic ionizing radiation is quickly estimated. Through the comparison of quality assurance method and statistical method, it is verified whether the hypothetical radiation situation is the same as the actual situation. The experimental results showed that this method can quickly and accurately estimate the dose rate of iatrogenic ionizing radiation, and give the corresponding biomedical protection measures in time.

Key words: iatrogenic ionizing radiation, dose rate estimation, quality assurance, statistics, radiation effect, radiation damage, medical biomedical protection

董亚军, 程强力. 医源性电离辐射剂量率估算与生物医学防护研究[J]. 影像科学与光化学, 2022, 40(3): 469-473.

DONG Yajun, CHENG Qiangli. The Dose Rate Estimation and Medical Biomedical Protection of Iatrogenic Ionizing Radiation[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2022, 40(3): 469-473.

参考文献

[1] 韩林, 陆雪, 李杰, 等. 双着丝粒体半自动与人工分析估算生物剂量的比较研究[J]. 中华放射医学与防护杂志, 2020,40(11):826-831.
[2] 李爽, 陆雪, 陈德清, 等. 不同结构类型双着丝粒体建立的剂量-效应曲线估算剂量可行性研究[J]. 中华放射医学与防护杂志, 2020,40(4):273-277.
[3] 谷庆, 嵇建峰, 郑晓. 电离辐射通过CXCL12/CXCR4信号轴调控肿瘤生物学行为的研究进展[J]. 中华放射医学与防护杂志, 2019,39(12):955-960.
[4] 高宇, 王平, 田崇彬, 等. 放射工作人员血清中8-羟基脱氧鸟苷水平研究[J]. 中华放射医学与防护杂志, 2018,38(4):253-257.
[5] 周光居, 刘善收, 赵光锋, 等. CT检查一次性成功率对伤员辐射暴露量的影响[J]. 中华急诊医学杂志, 2019,28(7):898-901.
[6] 党旭红, 王放, 左雅慧, 等. 电离辐射对人肝细胞MXR7基因表达的影响及放射性工作人员外周血MXR7的表达分析[J]. 辐射防护, 2018,38(6):517-521.
[7] 金大玉, 印有亮. 山莨菪碱对电离辐射损伤防护作用的实验研究[J]. 听力学及言语疾病杂志, 2018,26(5):537-538.
[8] 徐守龙, 邹树梁, 黄有骏, 等. CCD与CMOS像素传感器γ射线电离辐射响应特性对比研究[J]. 发光学报, 2018,39(6):815-822.
[9] 朱静芬, 滕跃, 王畅, 等. γ-H2AX免疫荧光分析技术评估CT辐射损伤的临床研究[J]. 放射学实践, 2018,33(8):876-880.
[10] 周瑾, 邹燕兰, 孙彦婷, 等. 江苏省某肿瘤专科医院放射工作人员个人剂量[J]. 环境与职业医学, 2018,35(4):352-355.
[11] 于利, 刘军. 天津市红桥区医用X射线诊断机房环境电离辐射调查[J]. 环境与健康杂志, 2018,35(2):184-185.
[12] 龚佳梦, 展永, 耿金鹏, 等. 太空电离辐射时长对金莲花基因多态性的影响[J]. 武汉科技大学学报, 2019,42(5):365-368.
[13] 刘梦雅, 袁慧, 高洁, 等. 电离辐射致认知功能损伤大鼠模型的研究[J]. 中国比较医学杂志, 2019,29(2):72-77.
[14] 梁鑫, 潘秀颉, 李雪萍, 等. 电离辐射诱导肺上皮细胞发生上皮间质转化[J]. 安徽医科大学学报, 2018,53(8):1155-1160.
[15] 沈莹. PCI术中护士有效辐射剂量的测量及DNA损伤研究[D].长春:吉林大学,2016.
[16] Mendiola-Cruz M T, Morales-Ramírez P.Repair kinetics of gamma-ray induced DNA damage determined by the single cell gel electrophoresis assay in murine leukocytes in vivo[J]. Mutation Research, 1999,433(1):45-52.

医源性电离辐射剂量率估算与生物医学防护研究

The Dose Rate Estimation and Medical Biomedical Protection of Iatrogenic Ionizing Radiation

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 0

编辑推荐

Metrics

本文评价