利用超分子作用提高竹红菌乙素的水溶性:金刚烷修饰的竹红菌乙素的合成及其环糊精聚合物包结物的光动力活性研究

doi:10.7517/j.issn.1674-0475.2007.05.380

影像科学与光化学 ›› 2007, Vol. 25 ›› Issue (5): 380-386.DOI: 10.7517/j.issn.1674-0475.2007.05.380

利用超分子作用提高竹红菌乙素的水溶性:金刚烷修饰的竹红菌乙素的合成及其环糊精聚合物包结物的光动力活性研究

乔瑞^1,2, 曾章华^1,2, 刘岩岩^1,2, 陈景荣¹, 李草¹, 王雪松¹, 张宝文¹

1. 中国科学院, 理化技术研究所, 北京, 100080;
2. 中国科学院, 研究生院, 北京, 100039

收稿日期:2007-03-19 修回日期:2007-04-06 出版日期:2007-09-23 发布日期:2007-09-23
通讯作者: 王雪松,xswang@mail.ipc.ac.cn;张宝文,g203@mail.ipc.ac.cn.

Using Supramolecular Interaction to Improve the Water Solubility of Hypocrellin B:Synthesis of Adamantane-Modified HB and the Photodynamic Activity Study of Its Polymeric β-CD Inclusion System

QIAO Rui^1,2, ZENG Zhang-hua^1,2, LIU Yan-yan^1,2, CHEN Jing-rong¹, LI Cao¹, WANG Xue-song¹, ZHANG Bao-wen¹

1. Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, P. R. China;
2. Graduate University of the Chinese Academy of Sciences, Beijing 100039, P. R. China

Received:2007-03-19 Revised:2007-04-06 Online:2007-09-23 Published:2007-09-23

摘要/Abstract

摘要： 本文设计合成了金刚烷修饰的竹红菌乙素衍生物,利用环糊精聚合物与金刚烷基团间的包结作用制备了基于竹红菌乙素的水溶性光敏体系,并通过顺磁共振技术研究了该光敏体系的活性氧产生能力.

关键词: 竹红菌乙素, 金刚烷, 环糊精聚合物, 包结作用, 光动力活性

Abstract: An adamantane-modified hypocrellin B was designed and synthesized, and was dissolved in aqueous solutions by way of the supramolecular inclusion interaction between the adamantane group and β-cyclodextrin polymer. ESR technique was applied to study the photodynamic activities of the aqueous solution of the adamantane-modified hypocrellin B and β-cyclodextrin polymer.

Key words: hypocrellin B, adamantane, cyclodextrin polymer, inclusion interaction, photodynamic activity

中图分类号:

乔瑞, 曾章华, 刘岩岩, 陈景荣, 李草, 王雪松, 张宝文. 利用超分子作用提高竹红菌乙素的水溶性:金刚烷修饰的竹红菌乙素的合成及其环糊精聚合物包结物的光动力活性研究[J]. 影像科学与光化学, 2007, 25(5): 380-386.

QIAO Rui, ZENG Zhang-hua, LIU Yan-yan, CHEN Jing-rong, LI Cao, WANG Xue-song, ZHANG Bao-wen. Using Supramolecular Interaction to Improve the Water Solubility of Hypocrellin B:Synthesis of Adamantane-Modified HB and the Photodynamic Activity Study of Its Polymeric β-CD Inclusion System[J]. Imaging Science and Photochemistry, 2007, 25(5): 380-386.

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利用超分子作用提高竹红菌乙素的水溶性:金刚烷修饰的竹红菌乙素的合成及其环糊精聚合物包结物的光动力活性研究

Using Supramolecular Interaction to Improve the Water Solubility of Hypocrellin B:Synthesis of Adamantane-Modified HB and the Photodynamic Activity Study of Its Polymeric β-CD Inclusion System

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