表面等离子共振传感器的原理与进展

doi:10.7517/j.issn.1674-0475.2017.01.015

摘要/Abstract

摘要：

表面等离子共振光谱（Surface Plasmon Resonance，SPR）是近年来得到快速发展的一门技术。它是一种无标记的、可用于实时定量检测某些固定于传感芯片上的组分与被结合物种间的绑定亲合度（binding affinity）、且可用于对相对小量物质进行检测的重要手段。由于它可方便地研究不同生物或化学物种的有关反应与动力学问题，因此具有重要的实用意义，受到广泛关注和重视。本文对有关等离子共振现象的形成及其作为敏感检测手段的机制、原理和改进等问题作了简要的介绍。

关键词: 表面等离子共振, 传感器, 纳米球刻蚀法, 贵金属纳米颗粒, 超常光学传输

Abstract:

Surface plasmon resonance (SPR) is a high sensitivity detection technology that was rapidly developed in recent years. It is a label-free method with the capability of real-time to measure quantitatively the binding affinity between foreign species and some receptor components located on chips. It is also used as an important tool for detecting relatively small amounts of materials interested. Due to the capability to study the kinetics of chemical reactions, this method possesses important significance for the studying of interaction between drugs and its ligand molecule for new drug development. Under this reason, extensive attention for this method has been exhibited. In this paper, the formation of SPR phenomenon and its principle, mechanism for using as a sensitive sensor and its improvement have been briefly introduced and discussed.

Key words: surface plasmon resonance (SPR), sensor, nanosphere lithography(NSL), noble metal nanoparticles, extraordinary optical transmission(EOT)

吴世康. 表面等离子共振传感器的原理与进展[J]. 影像科学与光化学, 2017, 35(1): 15-25.

WU Shikang. Principle and Progress for the Surface Plasmon Resonance Sensor[J]. Imaging Science and Photochemistry, 2017, 35(1): 15-25.

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