影像科学与光化学 ›› 2022, Vol. 40 ›› Issue (5): 1098-1102.DOI: 10.7517/issn.1674-0475.220126

• 综述与论文 • 上一篇    下一篇

磁共振-经直肠超声靶向穿刺联合病理大切片在前列腺癌诊断中的应用

关义满1, 李沛2, 房勤茂1   

  1. 1. 河北医科大学第三医院超声科, 河北 石家庄 050000;
    2. 河北省深州市医院超声科, 河北 深州 053800
  • 收稿日期:2022-01-14 发布日期:2022-09-13
  • 通讯作者: 关义满
  • 基金资助:
    河北省2016年医学科学研究重点课题计划(20160584)

Application of Magnetic Resonance-transrectal Ultrasound Puncture Combined with Large Pathological Section in the Diagnosis of Prostate Cancer

GUAN Yiman1, LI Pei2, FANG Qinmao1   

  1. 1. Department of Ultrasound, The Third Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, P. R. China;
    2. Department of Ultrasound, Shenzhou Hospital, Hebei Province, Shenzhou 053800, Hebei, P. R, China
  • Received:2022-01-14 Published:2022-09-13

摘要: 分析磁共振-经直肠超声靶向穿刺联合前列腺病理大切片对前列腺癌精准诊断的优势。以125例疑似前列腺癌患者为研究对象,根据穿刺方法分为对照组(60例)和研究组(65例)。对照组进行经直肠超声引导下常规系统穿刺,研究组进行磁共振-经直肠超声靶向穿刺结合常规系统穿刺,研究组患者进行磁共振-经直肠超声靶向穿刺后共确诊50例患者为前列腺癌,对其进行前列腺癌根治术,后将25例患者病理标本制作为大切片,另25例制作为常规切片。与对照组相比,研究组穿刺总针数、前列腺癌阳性针数较低(P<0.05)。与对照组相比,研究组穿刺阳性患者较高(P<0.05)。与对照组相比,研究组患者穿刺术后并发症发生率较低(P<0.05)。病理大切片组神经累及率、包膜累及率均高于常规切片组(P<0.05)。两组患者病理T分期对比,病理大切片组对pT≥3检出例数更高(P<0.05)。磁共振-经直肠超声靶向穿刺联合前列腺病理大切片对于前列腺癌的诊断价值较高。

关键词: 磁共振-经直肠超声靶向穿刺, 前列腺病理大切片, 前列腺癌, 诊断优势

Abstract: Analyzed the advantages of MRI-transrectal ultrasound targeted puncture combined with large prostate pathological slices for accurate diagnosis of prostate cancer. 125 patients with suspected prostate cancer were selected as research objects in the study. According to the puncture method they were divided into 60 cases in the control group and 65 cases in the study group. The control group underwent conventional systematic puncture guided by transrectal ultrasound, and the study group underwent magnetic resonance-transrectal ultrasound puncture combined with conventional system puncture, the patients in the research group underwent magnetic resonance-transrectal ultrasound targeted puncture, a total of 50 patients were diagnosed as prostate cancer, and underwent radical resection of prostate cancer. Then the pathological specimens of 25 patients were collected, and made into large slices, and the other 25 cases were made into regular slices. Compared with the control group, the total number of puncture needles and the number of positive needles for prostate cancer in the study group were lower (P<0.05), the number of patients with positive puncture was higher (P<0.05), the incidence of complications after puncture was lower (P<0.05). Compared with the conventional section group, the incidence of nerve involvement and capsule involvement in the pathological large section group was higher (P<0.05). In the comparison of pathological T staging between the two groups, the number of pT ≥ 3 cases detected in the large pathological section group was higher (P<0.05). Magnetic resonance-transrectal ultrasonography combined with prostate pathological large slices has a higher diagnostic value for prostate cancer.

Key words: magnetic resonance-transrectal ultrasound puncture, prostate pathology large section, prostate cancer, diagnostic advantages