Imaging Science and Photochemistry ›› 2019, Vol. 37 ›› Issue (6): 578-583.DOI: 10.7517/issn.1674-0475.190521

• Review and Articles • Previous Articles     Next Articles

The Value of Prenatal Ultrasound Combined with MRI in Screening Fetal Central Nervous System Malformations

XIANG Haibo, CHEN Huadong, LIU Liu, HUANG Zhihua, ZHAO Huiyan   

  1. Department of Radiology, Western Medicine Department, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi 445000, Hubei, P. R. China
  • Received:2019-05-21 Online:2019-11-15 Published:2019-11-15

Abstract: The value of prenatal ultrasound combined with magnetic resonance imaging (MRI) in screening fetal central nervous system (CNS) malformations was analyzed in this study. From January 2016 to February 2019, 196 pregnant women suspected of fetal CNS malformation were selected as the subjects of study. All pregnant women were examined by prenatal ultrasound and MRI. The postpartum results showed that 84 cases (42.86%) had CNS malformation. The sensitivity, specificity and accuracy of the prenatal ultrasound in screening fetal CNS deformities were 80.95% (68/84), 76.79% (86/112), 78.57% (154/196),while the prenatal MRI were 88.10% (74/84), 82.14% (92/112), 84.69% (166/196). The sensitivity, specificity and accuracy of the prenatal ultrasound combined with MRI were 97.62% (82/84), 94.64% (106/112), 95.92% (188/196), which were significantly higher than single method, the difference was statistically significant (P< 0.05). And there was no significant difference between prenatal ultrasound and MRI (P>0.05). This study confirms that prenatal ultrasound and MRI have the good screening value for fetal CNS malformation, and the combination of them has the higher screening value.

Key words: prenatal, ultrasound, magnetic resonance imaging, fetal central nervous system malformations, screening value