The Screening Value of Prenatal Ultrasound for Fetal Central Nervous Malformation in Early and Mid Pregnancy

doi:10.7517/issn.1674-0475.200501

Abstract

Abstract: The value of prenatal ultrasound in screening for fetal central nervous system malformations (CNSM) in early pregnancy and mid pregnancy was analyzed. 2298 pregnant women were selected as the subjects of this study, who were given prenatal ultrasound examination in early pregnancy (11-13+6 weeks) and mid pregnancy (14-27+6 weeks). The postpartum ultrasound or pathological examination showed that there were 200 cases (8.70%) of fetal CNSM. The coincidence rate of fetal CNSM in early pregnancy combined with mid pregnancy ultrasound was significantly higher than that in early pregnancy (P<0.05). The sensitivity, specificity and accuracy of early pregnancy combined with mid pregnancy ultrasound was significantly higher than those of early pregnancy (P<0.05). This study confirms that the prenatal ultrasound screening of fetal CNSM can be brought forward to early pregnancy, which is beneficial to early screening of fetal CNSM. But in order to have better screening effect, it still needs to be supplemented by ultrasound in mid pregnancy.

Key words: early pregnancy, mid pregnancy, prenatal ultrasound, fetal, central nervous malformation, screening

CAI Teng, JI Yamei. The Screening Value of Prenatal Ultrasound for Fetal Central Nervous Malformation in Early and Mid Pregnancy[J]. Imaging Science and Photochemistry, 2020, 38(6): 1047-1051.

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