The Diagnostic Efficiency of IVIM-DWI in Benign and Malignant Ovarian Tumors and the Correlation with Tumor Markers and Clinicopathological Factors

doi:10.7517/issn.1674-0475.201015

Abstract

Abstract: The aim of this study was to investigate the value of introvoxel incoherent motion diffusion-weighted magnetic resonance imaging (IVIM-DWI) in the diagnosis of benign and malignant ovarian tumor. There were 108 patients with ovarian tumors who were selected to compare the differences of IVMI-DWI parameters between benign and malignant tumors. The results showed that the IVIM-DWI parameters including apparent diffusion coefficient (ADC), slow diffusion coefficient (D_slow) and fast diffusion coefficient score (f value) of malignant tumor were lower than that of benign tumor (P<0.05). The area under ROC curve of ADC, Dslow and f value in the diagnosis of malignant ovarian tumor were 0.816, 0.915 and 0.852, respectively (P<0.05). ADC and D_slow were negatively correlated with carbohydrate antigen 125(CA125) (r=-0.457 and -0.553, P<0.05). The ADC in patients with clinical stage Ⅲ-Ⅳ was significantly lower than that of patients Ⅰ-Ⅱ (P<0.05). In a word, IVIM-DWI parameters have a certain application value in the diagnosis of benign and malignant ovarian tumors, and the ADC, D_slow levels are correlated with CA125 and clinical stage of patients with malignant tumors.407

Key words: introvoxel incoherent motion diffusion-weighted magnetic resonance imaging (IVIM-DWI), ovarian tumor, carbohydrate antigen 125, clinicopathology

LIN Dong, HUANG Jiajie, WU Shangwen, QIN Ni, XU Huali. The Diagnostic Efficiency of IVIM-DWI in Benign and Malignant Ovarian Tumors and the Correlation with Tumor Markers and Clinicopathological Factors[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2021, 39(3): 407-411.

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