The Relationship between the Five Parameters of DCE-MRI and the Disease Activity of Rheumatoid Arthritis and Its Clinical Value

doi:10.7517/issn.1674-0475.210309

Abstract

Abstract: The correlation between the five parameters of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) and the disease activity of patients with rheumatoid arthritis (RA) and the clinical value of joint prediction of short-term prognosis. A total of 105 RA patients were selected as the research objects. They were divided into a good prognosis group (80 cases) and a poor prognosis group (25 cases) according to the treatment response after 6 months of treatment. The results showed that RE, MRE, ME, Slope_max and AUC in DCE-MRI showed an increasing trend with the increase of disease activity, and were positively correlated with disease activity (r=0.759, 0.803, 0.763, 0.666, 0.724, P<0.05). Significantly related to the short-term prognosis. The five parameters of DCE-MRI examination combined predict the short-term prognosis AUC of 0.937, 95%CI of 0.872-0.975, P<0.001, sensitivity of 80.00%, specificity of 95.00%, significantly better than individual forecast.It is suggested that the five parameters of DCE-MRI examination can be used as a reliable method to clinically evaluate the severity of RA and predict the short-term prognosis, and provide a scientific evidence-based basis for the clinic.

Key words: rheumatoid arthritis, disease activity, dynamic contrast enhanced magnetic resonance imaging, short-term prognosis, predictive value

ZHENG Jing, REN Shuiming, ZHANG Fengxiang, GAO Qian, GAO Jing, YANG Yongmei, GAO Kaile. The Relationship between the Five Parameters of DCE-MRI and the Disease Activity of Rheumatoid Arthritis and Its Clinical Value[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2021, 39(5): 721-726.

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